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Opthalmic sensor

  • US 20070030443A1
  • Filed: 08/06/2004
  • Published: 02/08/2007
  • Est. Priority Date: 08/07/2003
  • Status: Active Grant
First Claim
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1. An ophthalmic sensor, comprising:

  • an ophthalmic device having a polymer matrix; and

    a molecular sensing moiety in and/or on said ophthalmic device, wherein the molecular sensing moiety is capable of interacting or reacting with sugar to provide an optical signal which is indicative of sugar level in an ocular fluid and is covalently attached to the polymer matrix by copolymerizing a lens-forming material including a compound having the structural formula (1) or (2);

    embedded image embedded image wherein R′

    is H or a C3-C25 radical having an olefinically unsaturated group;

    R is H, NR1R2, CN, OCH3, or a radical constituent capable of donating an electron to or accenting an electron from adjacent aromatic system, wherein R1 is H or C1-C6 alkyl while R2 is C1-C6 alkyl or a C3-C25 radical terminated with an olefinically unsaturated group, provided that at least one of R′ and

    R has an olefinically unsaturated group; and

    n is an integer from 1 to 5.

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