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Detection of NGAL in chronic renal disease

  • US 20070037232A1
  • Filed: 10/13/2005
  • Published: 02/15/2007
  • Est. Priority Date: 03/31/2005
  • Status: Abandoned Application
First Claim
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1. A method for the detection of worsening chronic renal failure in a mammal, comprising the steps of:

  • 1) providing a baseline fluid sample from a mammalian subject;

    2) providing at least one subsequent fluid sample from the subject;

    3) detecting the quantity of NGAL in each sample; and

    4) comparing the quantity of NGAL in the subsequent sample to the quantity of NGAL in the baseline sample, an increased quantity in the subsequent sample indicating that renal tubular cell injury is worsening in the subject.

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