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Formulations and methods for providing progestin-only contraception while minimizing adverse side effects associated therewith

  • US 20070037780A1
  • Filed: 08/15/2005
  • Published: 02/15/2007
  • Est. Priority Date: 08/15/2005
  • Status: Active Grant
First Claim
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1. A method of providing progestin-only contraception to a woman while minimizing adverse side effects associated with the progestin-only contraception, comprising:

  • transdermally administering a formulation having either norethindrone or norethindrone acetate as the sole active hormonal agent to the woman, at a rate and an amount that provides a minimum norethindrone serum level of at least about 160 pg/ml in order to cause and sustain physiologic events in the woman resulting in contraception, and also provides a maximum norethindrone serum level of less than about 2400 pg/ml in order to avoid a significant incidence of adverse side effects.

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