Arrangements, systems and methods capable of providing spectral-domain polarization-sensitive optical coherence tomography

• US 20070038040A1
• Filed: 04/24/2006
• Published: 02/15/2007
• Est. Priority Date: 04/22/2005
• Status: Abandoned Application

• Current Assignee: The General Hospital Corporation (Mass General Brigham, Inc.)
• Original Assignee: The General Hospital Corporation (Mass General Brigham, Inc.)
• Inventors: Mujat, Mircea, Park, Boris, Deboer, Johannes, Cense, Abraham
• Application Number:
  US11/410,937
• Publication Number:
  US 20070038040A1
• Time in Patent Office: Days
• US Class Current: 600/310
• CPC Class Codes: A61B 3/1005 for measuring distances inside the eye, e.g. thickness of the cornea A61B3/11 takes precedence
• CPC Class Codes: A61B 3/102 for optical coherence tomography [OCT]
• CPC Class Codes: A61B 3/1176 for determining lens opacity, e.g. cataract
• CPC Class Codes: G01N 21/21 Polarisation-affecting properties G01N21/19 takes precedence
• CPC Class Codes: G01N 21/4795 spatially resolved investigating of object in scattering medium in vivo A61B

Abstract

Systems, arrangements and methods for separating an electromagnetic radiation and obtaining information for a sample using an electromagnetic radiation are provided. In particular, the electromagnetic radiation can be separated into at least one first portion and at least one second portion according to at least one polarization and at least one wave-length of the electromagnetic radiation. The first and second separated portions may be simultaneously detected. Further, a first radiation can be obtained from the sample and a second radiation may be obtained from a reference, and the first and second radiations may be combined to form a further radiation, with the first and second radiations being associated with the electro-magnetic radiation. The information is provided as a function of first and second portions of the further radiations that have been previously separated and can be analyzed to extract birefringent information characterizing the sample.

Claims

1. An apparatus for separating an electromagnetic radiation, comprising:

a first arrangement configured to separate the electromagnetic radiation into at least one first portion and at least one second portion according to at least one polarization and at least one wave-length of the electromagnetic radiation; and

a second arrangement configured to simultaneously detect the separated first and second portions.

2. The apparatus according to claim 1, wherein the second arrangement comprises a detection arrangement which includes a single row of detection elements.

3. The apparatus according to claim 1, wherein the second arrangement comprises a first detection arrangement and a second detection arrangement, wherein each of the first and second detection arrangements includes a single row of detection elements.

4. The apparatus according to claim 1, wherein the first arrangement includes a first element which is configured to separate the electromagnetic radiation into the first and second portions based on the at least one polarization, and a second element which is configured to separate the electromagnetic radiation into the first and second portions based on the at least one wave-length.

5. The apparatus according to claim 4, wherein the first element follows the second element in an optical path of the electromagnetic radiation.

6. The apparatus according to claim 5, wherein the first arrangement further includes a third light directing element which is provided in the optical path in a proximity of the first and second elements.

7. The apparatus according to claim 6, wherein the third element is provided between the first and second elements.

8. The apparatus according to claim 6, wherein the third element follows the first and second elements in the optical path.

9. The apparatus according to claim 5, wherein the first arrangement further includes third and fourth light directing elements which are provided in the optical path following the first and second elements.

10. The apparatus according to claim 9, wherein each of the third and fourth elements directs at least one of the respective separated portions toward the second element.

11. The apparatus according to claim 4, wherein the second element follows the first element in an optical path of the electro-magnetic radiation.

12. An apparatus for obtaining information for a sample using an electromagnetic radiation, comprising:

a first arrangement configured to generate the electromagnetic radiation;

a second interferometric arrangement configured to receive and combine a first radiation from the sample and a second radiation from a reference into a further radiation, the first and second radiations being associated with the electromagnetic radiation; and

a third arrangement configured to separate the further radiation into at least one first portion and at least one second portion according to at least one polarization and at least one wave-length of the electromagnetic radiation; and

a fourth arrangement configured to simultaneously detect the separated first and second portions, and obtain the information as a function of the separated first and second portions.

13. The apparatus according to claim 12, wherein the first arrangement includes a further arrangement configured to control a polarization of the generated electromagnetic radiation.

14. The apparatus according to claim 12, wherein the fourth arrangement comprises a detection arrangement which includes a single row of detection elements.

15. The apparatus according to claim 12, wherein the third arrangement includes a first element which is configured to separate the electromagnetic radiation into the first and second portions based on the at least one polarization, and a second element which is configured to separate the electromagnetic radiation into the first and second portions based on the at least one wave-length.

16. The apparatus according to claim 15, wherein the first element follows the second element in an optical path of the electromagnetic radiation.

17. The apparatus according to claim 16, wherein the third arrangement further includes a third light directing element which is provided in the optical path at least one of (i) in a proximity of the first and second elements, or (ii) following the first and second elements.

18. The apparatus according to claim 17, wherein the third element at least one of (i) is provided between the first and second elements, or (ii) follows the first and second elements in the optical path.

19. The apparatus according to claim 17, wherein each of the third and fourth elements directs at least one of the respective separated portions toward the second element.

20. The apparatus according to claim 15, wherein the second element follows the first element in an optical path of the electromagnetic radiation.

21. A method for separating an electromagnetic radiation, comprising:

separating the electromagnetic radiation into at least one first portion and at least one second portion according to at least one polarization and at least one wave-length of the electro-magnetic radiation; and

simultaneously detecting the separated first and second portions.

22. A method for obtaining information for a sample using an electromagnetic radiation, comprising:

receiving and combining a first radiation from the sample and a second radiation from a reference into a further radiation, the first and second radiations being associated with the electromagnetic radiation;

simultaneously detecting first and second portions of the further radiation that were separated from the further radiation according to at least one polarization and at least one wave-length of the electromagnetic radiation; and

obtaining the information as a function of the separated first and second portions.