Methods and systems for ultrasound delivery through a cranial aperture
First Claim
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1. A system for delivering ultrasound energy to an intracranial space of a patient, the system comprising:
- an access device having an aperture and configured to be applied to a patient'"'"'s skull;
an ultrasound device coupled with and extending at least partially through the access device, the ultrasound device including proximal and distal ends;
at least one acoustically conductive medium juxtaposed at the distal end of the ultrasound device; and
means for cooling the acoustically conductive medium to a temperature below at least one of room temperature and body temperature.
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Abstract
A method for delivering ultrasound energy to a patient'"'"'s intracranial space includes forming at least one aperture in the patient'"'"'s skull, introducing at least one acoustically conductive medium into the intracranial space to contact brain tissue of the patient, advancing an ultrasound device at least partially through the aperture in the skull, and transmitting ultrasound energy to the intracranial space, using the ultrasound device. In some embodiments, the acoustically conductive medium may be cooled to help regulate the temperature of the patient'"'"'s brain tissue.
97 Citations
37 Claims
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1. A system for delivering ultrasound energy to an intracranial space of a patient, the system comprising:
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an access device having an aperture and configured to be applied to a patient'"'"'s skull;
an ultrasound device coupled with and extending at least partially through the access device, the ultrasound device including proximal and distal ends;
at least one acoustically conductive medium juxtaposed at the distal end of the ultrasound device; and
means for cooling the acoustically conductive medium to a temperature below at least one of room temperature and body temperature. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A method for delivering ultrasound energy to a patient'"'"'s intracranial space, the method comprising:
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forming at least one aperture in the patient'"'"'s skull;
introducing at least one acoustically conductive medium into the intracranial space to contact brain tissue of the patient;
advancing an ultrasound device at least partially through the aperture in the skull;
cooling the acoustically conductive medium; and
transmitting ultrasound energy to the intracranial space, using the ultrasound device. - View Dependent Claims (17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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31. A method for delivering ultrasound energy to a patient'"'"'s intracranial space and cooling a patient'"'"'s brain tissue, the method comprising:
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forming at least one aperture in the patient'"'"'s skull;
introducing at least one acoustically conductive medium into the intracranial space to contact brain tissue of the patient;
advancing an ultrasound device at least partially through the aperture in the skull;
cooling at least a portion of the patient'"'"'s brain tissue; and
transmitting ultrasound energy to the intracranial space, using the ultrasound device. - View Dependent Claims (32, 33, 34, 35, 36, 37)
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Specification