Baroreflex stimulation system to reduce hypertension
First Claim
1. An implantable medical device, comprising:
- a pulse generator to generate a baroreflex stimulation signal as part of a baroreflex therapy;
a lead to be electrically connected to the pulse generator and to be intravascularly fed into a heart, the lead including an electrode to be positioned in or proximate to the heart to deliver the baroreflex signal to a baroreceptor region in or proximate to the heart;
a sensor to sense a physiological parameter regarding an efficacy of the baroreflex therapy and to provide a signal indicative of the efficacy of the baroreflex therapy; and
a controller connected to the pulse generator to control the baroreflex stimulation signal and to the sensor to receive the signal indicative of the efficacy of the baroreflex therapy.
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Accused Products
Abstract
The present invention is an implantable medical device comprising, a pulse generator to generate a baroreceptor stimulation signal as part of a baroreflex therapy, a lead to be electrically connected to the pulse generator and to be intravascularly fed into a heart, the lead including an electrode to be positioned in or proximate to the heart to deliver the baroreceptor signal to a baroreceptor region in or proximate to the heart, a sensor to sense a physiological parameter regarding the need to modify the baroreflex system and to provide a signal indicative of the need to modify the baroreflex system and a controller connected to the pulse generator to control the baroreceptor stimulation signal and to the sensor to receive the signal indicative of the need to modify the baroreflex system.
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Citations
24 Claims
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1. An implantable medical device, comprising:
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a pulse generator to generate a baroreflex stimulation signal as part of a baroreflex therapy;
a lead to be electrically connected to the pulse generator and to be intravascularly fed into a heart, the lead including an electrode to be positioned in or proximate to the heart to deliver the baroreflex signal to a baroreceptor region in or proximate to the heart;
a sensor to sense a physiological parameter regarding an efficacy of the baroreflex therapy and to provide a signal indicative of the efficacy of the baroreflex therapy; and
a controller connected to the pulse generator to control the baroreflex stimulation signal and to the sensor to receive the signal indicative of the efficacy of the baroreflex therapy. - View Dependent Claims (2, 3, 4, 5)
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6. An implantable baroreflex stimulator, comprising:
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means for delivering baroreflex therapy through a lead intravascularly fed through at least a portion of the heart to a baroreceptor region proximate to a heart to inhibit sympathetic activity; and
means for providing feedback regarding an efficacy of the baroreflex therapy for use to control delivery of the baroreflex therapy. - View Dependent Claims (7, 8, 9, 10, 11, 12)
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13. A method, comprising:
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applying baroreflex therapy, including electrically stimulating a baroreceptor region in or near a heart using a lead intravascularly fed into at least a portion of the heart;
sensing a physiologic parameter indicative of an efficacy of the baroreflex therapy; and
modifying the baroreflex therapy based on the physiological parameter. - View Dependent Claims (14, 15, 16, 17, 18)
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19. An implantable medical device, comprising:
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a pulse generator to generate a baroreflex stimulation signal as part of a baroreflex therapy;
a lead to be electrically connected to the pulse generator, the lead including an electrode to deliver the baroreflex signal to a baroreflex target;
a sensor to sense a physiological parameter regarding an efficacy of the baroreflex therapy and to provide a signal indicative of the efficacy of the baroreflex therapy; and
a controller connected to the pulse generator to control the baroreflex stimulation signal and to the sensor to receive the signal indicative of the efficacy of the baroreflex therapy.
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20. A method, comprising:
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applying baroreflex therapy, including electrically stimulating a baroreceptor region using a lead with an electrode;
sensing a physiologic parameter indicative of an efficacy of the baroreflex therapy; and
modifying the baroreflex therapy based on the physiological parameter.
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21. An implantable medical device, comprising:
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a pulse generator to generate a baroreceptor stimulation signal as part of a baroreflex therapy;
a lead to be electrically connected to the pulse generator and to be intravascularly fed into a heart, the lead including an electrode to be positioned in or proximate to the heart to deliver the baroreceptor signal to a baroreceptor region in or proximate to the heart;
a sensor to sense a physiological parameter regarding the need to modify the baroreflex system and to provide a signal indicative of the need to modify the baroreflex system; and
a controller connected to the pulse generator to control the baroreceptor stimulation signal and to the sensor to receive the signal indicative of the need to modify the baroreflex system.
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22. An implantable baroreflex stimulator, comprising:
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means for delivering baroreflex therapy through a lead intravascularly fed through at least a portion of the heart to a baroreceptor region proximate to a heart to inhibit sympathetic activity; and
means for providing feedback regarding an efficacy of the baroreflex therapy for use to control delivery of the baroreflex therapy.
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23. A method, comprising:
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applying baroreflex therapy, including electrically stimulating a baroreceptor region in or near a heart using a lead intravascularly fed into at least a portion of the heart;
sensing a physiologic parameter indicative of the need to modify the baroreflex system; and
modifying the baroreflex therapy based on the physiological parameter.
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24. An implantable medical device, comprising:
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a pulse generator to generate a baroreceptor stimulation signal as part of a baroreflex therapy;
a lead adapted to be electrically connected to the pulse generator, the lead including an electrode to deliver the baroreceptor signal to a baroreceptor neural target;
a sensor to sense a physiological parameter and to provide a signal indicative of the need to modify the baroreflex system; and
a controller connected to the pulse generator to control the baroreceptor stimulation signal and to the sensor to receive the signal indicative of the need to modify the baroreflex system.
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Specification