Multi step photopatterning of skin
First Claim
Patent Images
1. A method of forming a patterned distribution of a material in or on skin, comprising:
- delivering a photoresponsive material to at least a skin region of a subject;
delivering a first patterned distribution of light of a first wavelength band at a first depth within or height above the skin region to cause a first transformation of the photoresponsive material at the first depth or height to a first modified form; and
delivering a second patterned distribution of light of a second wavelength band at a second depth within or height above the skin region sufficient to cause a second transformation of the photoresponsive material at the second depth or height to a second modified form.
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Abstract
Methods and systems for treating skin for aesthetic or health or other purposes are described. According to various embodiments, photoresponsive materials and light are delivered in controlled fashions to produce a patterned distribution of one or more material in or on the skin.
118 Citations
78 Claims
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1. A method of forming a patterned distribution of a material in or on skin, comprising:
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delivering a photoresponsive material to at least a skin region of a subject;
delivering a first patterned distribution of light of a first wavelength band at a first depth within or height above the skin region to cause a first transformation of the photoresponsive material at the first depth or height to a first modified form; and
delivering a second patterned distribution of light of a second wavelength band at a second depth within or height above the skin region sufficient to cause a second transformation of the photoresponsive material at the second depth or height to a second modified form. - View Dependent Claims (2, 3, 4, 5, 6, 7, 10, 32, 33, 34, 39, 45, 50, 51, 52, 53, 54, 55, 69, 70, 71, 72, 73, 74, 75, 76, 77)
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56. A method of producing a patterned distribution of material in skin, comprising:
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delivering a photoresponsive material to at least a skin region of a subject;
delivering light to the skin region according to a first pattern, the light having a first wavelength band and peak or time-average flux or fluence sufficient to produce a first response in the skin region;
delivering light to the skin region according to a second pattern, the light having a second wavelength band and peak or time-average flux or fluence sufficient to produce a second response in the skin region, the second response being modified by the first response in the areas of overlap between the first pattern and the second pattern; and
repeating one or more steps of delivering a photoresponsive material and delivering light to the skin region, wherein the repeated one or more steps produce a response that is modified by a previous response of the skin region to delivery of one or more of photoresponsive material and light. - View Dependent Claims (57, 58, 59)
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60. A system for delivering patterned light to skin, comprising:
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a first light source capable of producing light of a first wavelength band and peak or time-average flux or fluence;
a second light source capable of producing light of a second wavelength band and peak or time-average flux or fluence;
a controllable optical system configured to receive a first control signal generated according to a first pattern representing a first desired distribution of light of the first wavelength band and peak or time-average flux or fluence, and to receive a second control signal generated according to a second pattern representing a second desired distribution of light of the second wavelength band and peak or time-average flux or fluence, the controllable optical system responsive to the first control signal to aim and focus light of the first wavelength band at one or more selected skin locations within the first desired distribution, and responsive to the second control signal to aim and focus light of the second wavelength band at one or more selected skin locations within the second desired distribution; and
electronic circuitry configured to limit the flux and/or fluence of light produced by the light source to levels that are not significantly damaging to the skin at the skin surface. - View Dependent Claims (66, 68, 78)
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Specification