METHOD AND SYSTEM FOR ADAPTING A RADIATION THERAPY TREATMENT PLAN BASED ON A BIOLOGICAL MODEL
First Claim
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1. A method of adapting a treatment plan, the method comprising:
- preparing a treatment plan for a patient;
acquiring images of the patient;
performing deformable registration of the images;
acquiring data relating to a radiation dose delivered to the patient;
applying a biological model to relate the radiation dose delivered and a patient effect; and
adapting the treatment plan based on the deformable registration and the biological model.
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Abstract
A system and method of adapting a radiation therapy treatment plan. The method includes the acts of preparing a treatment plan for a patient, acquiring images of the patient, performing deformable registration of the images, acquiring data relating to a radiation dose delivered to the patient, applying a biological model relating the radiation dose delivered and a patient effect, and adapting the radiation therapy treatment plan based on the deformable registration and the biological model.
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Citations
24 Claims
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1. A method of adapting a treatment plan, the method comprising:
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preparing a treatment plan for a patient;
acquiring images of the patient;
performing deformable registration of the images;
acquiring data relating to a radiation dose delivered to the patient;
applying a biological model to relate the radiation dose delivered and a patient effect; and
adapting the treatment plan based on the deformable registration and the biological model. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A method of delivering radiation therapy to a patient, the method comprising:
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acquiring an on-line image of at least a portion of the patient while the patient is in a first position;
calculating a predictive radiation dose to be delivered to the patient; and
applying a biological model to determine a biological effect of the predictive radiation dose on the patient in the first position. - View Dependent Claims (19, 20, 21, 22, 23)
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24. A computer program embodied by a computer readable medium capable of being executed by a computer, the computer program for use in a treatment system, the computer program comprising:
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a treatment plan module operable to generate a treatment plan for a patient;
an image acquisition module operable to acquire images of at least a portion of the patient;
a deformation module operable to generate a deformable registration between at least two of the images; and
a modeling module operable to relate a radiation dose delivered to the patient and an effect of the radiation dose on the patient and to adapt the treatment plan based on the deformable registration and a biological model.
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Specification