Non-cylindrical prosthetic valve system for transluminal delivery
First Claim
1. A prosthetic valve assembly, comprising:
- a prosthesis frame comprising a first end, a second end, and a middle section therebetween; and
a valve engaged to the prosthesis frame;
wherein the first end comprises a first plurality of elongate structural members and a first plurality of expandable cells, the second end comprises a second plurality of elongate structural members and a second plurality of expandable cells, and the middle section comprises a third plurality of heterogeneous elongate structural members and a third plurality of expandable cells, wherein the expandable cells are defined by the elongate structural members in an enclosed arrangement.
2 Assignments
0 Petitions
Accused Products
Abstract
A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable prosthesis frame. If desired, one or more expandable anchors may be used. The prosthesis frame, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. Portions of the prosthesis frame may expand to a preset diameter to maintain coaptivity of the replacement valve and to prevent occlusion of the coronary ostia. The prosthesis frame is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart. When the outer sheath is retracted, the prosthesis frame expands to an expanded position such that the valve and prosthesis frame expand at the implantation site and the anchor engages the lumen wall. The prosthesis frame has a non-cylindrical configuration with a preset maximum expansion diameter region about the valve opening to maintain the preferred valve geometry. The prosthesis frame may also have other regions having a preset maximum expansion diameter to avoid blockage of adjacent structures such as the coronary ostia.
1112 Citations
92 Claims
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1. A prosthetic valve assembly, comprising:
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a prosthesis frame comprising a first end, a second end, and a middle section therebetween; and
a valve engaged to the prosthesis frame;
wherein the first end comprises a first plurality of elongate structural members and a first plurality of expandable cells, the second end comprises a second plurality of elongate structural members and a second plurality of expandable cells, and the middle section comprises a third plurality of heterogeneous elongate structural members and a third plurality of expandable cells, wherein the expandable cells are defined by the elongate structural members in an enclosed arrangement. - View Dependent Claims (2)
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3. A prosthetic valve assembly, comprising:
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a prosthesis frame comprising a first end, a second end, and a middle section therebetween; and
a valve engaged to the prosthesis frame;
wherein the first end comprises a first plurality of elongate structural members and a first plurality of expandable cells, the second end comprises a second plurality of elongate structural members and a second plurality of expandable cells, and the middle section comprises a third plurality of elongate structural members and a third plurality of heterogeneous expandable cells, wherein the expandable cells are defined by the elongate structural members in an enclosed arrangement.
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4. A prosthetic valve assembly, comprising:
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an expandable prosthesis frame having a heterogeneous configuration, the expandable prosthesis frame comprising a plurality of elongate structural members and a plurality of cells; and
a valve engaged to the prosthesis frame;
wherein each opening of the plurality of cells comprises an area and a shape and each elongate structural member of the plurality of elongate structural members comprises a length, a width, an axial cross-sectional shape and an axial cross-sectional area. - View Dependent Claims (5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25)
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26. A prosthetic valve assembly comprising:
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a prosthesis frame having a first and second end and having a reduced and expanded configuration, the frame comprising a first zone proximal the first end, a second zone proximal the second end, and a third zone therebetween, said zones positioned axially with respect to each other, wherein the fully expanded diameter of the first zone is different than that of the second zone; and
a valve engaged to the prosthesis frame. - View Dependent Claims (27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46)
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47. A prosthetic valve assembly for treating a patient, comprising:
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a valve for controlling blood flow;
a non-cylindrical means for maintaining and supporting the geometry of the valve means; and
an anchor attached to the non-cylindrical means. - View Dependent Claims (48)
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- 49. A prosthetic valve assembly comprising a prosthesis frame having a first zone, a second generally bulbous zone having a maximum expanded diameter greater than that of the first zone, and a valve support zone having a maximum expanded diameter smaller than those of the first and second zones.
- 55. A method of implanting the valve assembly in a patient, the method comprising providing a prosthetic valve assembly comprising a prosthesis frame having a first zone, a second generally bulbous zone having a maximum expanded diameter greater than that of the first zone, and a valve support zone having a maximum expanded diameter smaller than those of the first and second zones, said prosthetic valve assembly mounted onto a catheter suitable for percutaneous and vascular delivery and deploying said valve assembly within an appropriate native lumen of the patient.
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57. A method for treating a patient comprising:
inserting a self-expanding valve into the lumen of a previously-implanted cardiovascular device with a lumen of a patient. - View Dependent Claims (58, 59, 60, 61, 62, 63, 64, 65, 67, 68, 69, 70, 71, 72, 73)
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66. The method of treating a patient as in claim 66, wherein at least a portion of the at least one commissure post is moved at least about 2 mm.
- 74. A method for implanting a cardiovascular device comprising inserting an expandable heart valve into a vascular system of a patient, anchoring the expandable heart valve against a distal surface of one or more valve leaflets of the patient without contacting an annulus surface of the patient.
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77. A method for implanting a cardiovascular device comprising:
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providing a cardiovascular device located on a delivery system;
inserting the delivery system through an aortic arch of a patient from a first arterial access point;
inserting a snare from a second arterial access point;
grasping the delivery system with the snare; and
manipulating the snare to align the delivery system with a lumen of the patient'"'"'s aortic valve. - View Dependent Claims (78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92)
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Specification