Systems and methods for a multiple angle light scattering (MALS) instrument having two-dimensional detector array
First Claim
1. A system for detecting and identifying a particle in a liquid, the system comprising:
- a target zone;
a light source configured to generate a light beam and direct the light beam through the target zone;
an optic configured to collect and reflect light scattered by a particle in the target zone; and
a 2-dimensional detector camera configured to detect the reflected light.
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Accused Products
Abstract
A particle detection system uses a reflective optic comprising a curved surface to detect high angle scattered light generated by a particle in a liquid medium, when a laser beam is incident on the particle. When the particles transit the laser beam, light is scattered in all directions and is described by MIE scattering theory for particles about the size of the wavelength of light and larger or Rayleigh Scattering when the particles are smaller than the wavelength of light. By using the reflective optic, the scattered light can be detected over angles that are greater than normally obtainable.
52 Citations
20 Claims
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1. A system for detecting and identifying a particle in a liquid, the system comprising:
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a target zone;
a light source configured to generate a light beam and direct the light beam through the target zone;
an optic configured to collect and reflect light scattered by a particle in the target zone; and
a 2-dimensional detector camera configured to detect the reflected light. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A system for detecting and identifying a particle in a liquid, the system comprising:
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a flowcell comprising a flowing liquid media and a target zone;
a light source configured to generate a light beam and direct the light beam through the target zone;
an interface optic;
a reflective optic configured to collect and reflect light scattered by a particle carried by the liquid media through the target zone; and
a 2-dimensional detector camera configured to detect the reflected light. - View Dependent Claims (17, 18, 19, 20)
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Specification