Mucosal delivery tablet
First Claim
Patent Images
1. A tablet having at least one convex surface, said tablet having a ratio of tablet diameter D to the cup depth d (D/d) of 4-20 and a ratio of cup depth d to edge thickness h (d/h) of greater than 0.75.
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Accused Products
Abstract
Mucoadhesive tablets have a convex surface, a diameter to cup depth ratio of 4-20 and a cup depth to edge thickness ratio of greater than 0.75 swiftly adheres and conforms to the contacting tissue. The tablets are used to administer actives such as, for example, benzocaine.
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Citations
20 Claims
- 1. A tablet having at least one convex surface, said tablet having a ratio of tablet diameter D to the cup depth d (D/d) of 4-20 and a ratio of cup depth d to edge thickness h (d/h) of greater than 0.75.
- 9. A method of producing a bioadhesive system comprising preparing a solution comprising at least one solvent and a polymer mixture wherein the polymer mixture comprises at least one synthetic polycarboxylated polymer component and at least one polysaccharide component and drying the solution to form a solid, and compressing the solid to form a tablet, said tablet having at least one convex surface and having a ratio of tablet diameter D to the cup depth d (D/d) of 4-20 and a ratio of cup depth d to edge thickness h (d/h) of greater than 0.75.
- 19. A buccal delivery tablet comprising a bioadhesive composition and an active agent, tablet having at least one convex surface, said tablet having a ratio of tablet diameter D to the cup depth d (D/d) of 4-20 and a ratio of cup depth d to edge thickness h (d/h) of greater than 0.75.
Specification