Drug eluting coatings for a medical lead and method therefor
First Claim
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1. A medical lead comprising:
- a lead body extending from a first end portion to a second end portion; and
a coating disposed along a portion of the lead, wherein the coating includes at least one matrix polymer layer, at least one anti-inflammatory agent and at least one anti-proliferative agent.
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Abstract
A medical lead including a lead body extending from a first end portion to a second end portion and a coating disposed along a portion of the lead, wherein the coating includes at least one matrix polymer layer, at least one anti-inflammatory agent and at least one anti-proliferative agent.
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Citations
24 Claims
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1. A medical lead comprising:
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a lead body extending from a first end portion to a second end portion; and
a coating disposed along a portion of the lead, wherein the coating includes at least one matrix polymer layer, at least one anti-inflammatory agent and at least one anti-proliferative agent. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A medical lead comprising:
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a lead body extending from a proximal end portion to a distal end portion;
an electrode disposed along the lead body; and
a coating associated with at least a portion of the electrode, wherein the coating includes a layer of phosphorylcholine (PC), polyvinylpyrrolidone (PVP), poly(vinyl alcohol) (PVA), hyaluranic acid (HA), polyactive or a combination thereof. - View Dependent Claims (17, 18, 19, 20, 21, 22, 23)
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24. A method comprising:
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coating a portion of a medical lead with at least one matrix polymer layer, at least one anti-inflammatory agent and at least one anti-proliferative agent;
delivering the medical lead to a site of implantation; and
releasing at least one anti-inflammatory agent and at least one anti-proliferative agent from the coating so as to decrease the formation of a fibrotic capsule near an electrode of an implanted lead.
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Specification