Aqueous sanitizers, disinfectants, and/or sterilants with low peroxygen content

• US 20070053850A1
• Filed: 08/24/2006
• Published: 03/08/2007
• Est. Priority Date: 02/25/2005
• Status: Active Grant

• Current Assignee: Axenic Global LLC
• Original Assignee: Sbiomed Founders, LLC
• Inventors: Larson, Brian, Tichy, Daryl
• Granted Patent: US 7,511,007 B2
• Time in Patent Office: Days
• US Class Current: 424/53
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 25/22 containing ingredients stabilising the active ingredients
• CPC Class Codes: A01N 31/02 Acyclic compounds
• CPC Class Codes: A01N 37/16 containing the group; Thio analogues thereof
• CPC Class Codes: A01N 59/16 Heavy metals; Compounds thereof
• CPC Class Codes: A01N 59/20 Copper
• CPC Class Codes: A61K 2800/30 Characterized by the absence of a particular group of ingredients
• CPC Class Codes: A61K 2800/412 Microsized, i.e. having sizes between 0.1 and 100 microns
• CPC Class Codes: A61K 8/0241 Containing particulates characterized by their shape and/or structure see also A61K8/04, A61K8/11, and A61K8/14, further aspects are classified in A61K2800/40 and subcodes
• CPC Class Codes: A61K 8/046 Aerosols; Foams
• CPC Class Codes: A61K 8/19 containing inorganic ingredients
• CPC Class Codes: A61K 8/22 Peroxides; Oxygen; Ozone
• CPC Class Codes: A61K 8/34 Alcohols
• CPC Class Codes: A61K 8/38 Percompounds, e.g. peracids
• CPC Class Codes: A61L 2/0088 Liquid substances
• CPC Class Codes: A61L 2/186 Peroxide solutions
• CPC Class Codes: A61L 2202/24 Medical instruments, e.g. endoscopes, catheters, sharps
• CPC Class Codes: A61P 11/04 for throat disorders
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61P 31/02 Local antiseptics
• CPC Class Codes: A61P 31/04 : Antibacterial agents
• CPC Class Codes: A61P 31/10 : Antimycotics
• CPC Class Codes: A61P 31/12 : Antivirals
• CPC Class Codes: A61P 33/00 : Antiparasitic agents
• CPC Class Codes: A61P 43/00 : Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
• CPC Class Codes: A61Q 11/00 : Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
• CPC Class Codes: A61Q 17/005 : Antimicrobial preparations
• CPC Class Codes: A61Q 19/10 : Washing or bathing preparations
• CPC Class Codes: A61Q 5/02 : Preparations for cleaning the hair
• CPC Class Codes: C11D 3/48 : Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
• CPC Class Codes: C11D 7/02 : Inorganic compounds
• CPC Class Codes: C11D 7/06 : Hydroxides
• CPC Class Codes: C11D 7/261 : Alcohols; Phenols

Abstract

The present invention is drawn to disinfectant compositions, which are human safe, e.g., food grade or food safe. In one embodiment, an aqueous disinfectant composition can comprise an aqueous vehicle, including water, from 0.001 wt % to 10.0 wt % of a peroxygen, and an alcohol. Additionally, from 0.001 ppm to 50,000 ppm by weight of a transition metal based on the aqueous vehicle content can also be present. The composition can be substantially free of aldehydes. Alternatively or additionally, the transition metal can be in the form of a colloidal transition metal, such as colloidal silver or alloy thereof.

Claims

1. An aqueous disinfectant composition, comprising:

a) an aqueous vehicle, including;

i) water;

ii) from 0.001 wt % to 10.0 wt % of a peroxygen; and

iii) an alcohol;

b) from 0.001 ppm to 50,000 ppm by weight of a transition metal or alloy thereof based on the aqueous vehicle content,

with the proviso that the disinfectant composition is substantially free of aldehydes.

2. A composition as in claim 1, wherein the disinfectant composition is substantially free of chlorine and bromine-containing components.

3. A composition as in claim 1, wherein the disinfectant composition is substantially free of iodophore-containing components.

4. A composition as in claim 1, wherein the disinfectant composition is substantially free of phenolic-containing components.

5. A composition as in claim 1, wherein the disinfectant composition is substantially free of quaternary ammonium-containing components.

6. A composition as in claim 1, where the alcohol is present at from 0.001 wt % to 40 wt %.

7. A composition as in claim 1, wherein the alcohol is present at from 0.05 wt % to 20 wt %.

8. A composition as in claim 1, wherein the alcohol is present at from 0.1 wt % to 10 wt %.

9. A composition as in claim 1, wherein the alcohol is a C₁-C₂₄ alcohol.

10. A composition as in claim 9, wherein C₁-C₂₄ alcohol is selected from the group consisting of methanol, ethanol, propanols, butanols, pentanols, and mixtures thereof.

11. A composition as in claim 9, wherein the C₁-C₂₄ alcohol is a polyhydric alcohol.

12. A composition as in claim 11, wherein the polyhydric alcohol is glycerol.

13. A composition as in claim 11, wherein the polyhydric alcohol includes two alcohol groups.

14. A composition as in claim 11, wherein the polyhydric alcohol includes three alcohol groups.

15. A composition as in claim 1, wherein the transition metal or alloy thereof is a Group VI to Group XI transition metal or alloy thereof.

16. A composition as in claim 1, wherein the transition metal or alloy thereof is a Group X to Group XI transition metal or alloy thereof.

17. A composition as in claim 1, wherein the transition metal or alloy thereof is selected from the group consisting of ruthenium, rhodium, osmium, iridium, palladium, platinum, copper, gold, silver, alloys thereof, and mixtures thereof.

18. A composition as in claim 1, wherein the transition metal or alloy thereof is a colloidal transition metal or alloy thereof.

19. A composition as in claim 18, wherein the colloidal transition metal is colloidal silver.

20. A composition as in claim 18, wherein the colloidal transition metal or alloy thereof has an average particle size of from 0.001 μ

m to 1.0 μ

m.

21. A composition as in claim 18, wherein the colloidal transition metal or alloy thereof has an average particle size of from 0.030 μ

m to 0.5 μ

m.

22. A composition as in claim 1, wherein the transition metal or alloy thereof is an ionic transition metal.

23. A composition as in claim 1, wherein the transition metal or alloy thereof is present at from 15 ppm to 1500 ppm by weight.

24. A composition as in claim 1, wherein the peroxygen is a peracid.

25. A composition as in claim 24, wherein the peracid is an aliphatic peracid.

26. A composition as in claim 24, wherein the peracid is an aromatic peracid.

27. A composition as in claim 24, wherein the peracid is selected from the group consisting of peroxyformic acid, peroxyacetic acid, peroxyoxalic acid, peroxypropanoic acid, perlactic acid, peroxybutanoic acid, peroxypentanoic acid, peroxyhexanoic acid, peroxyadipic acid, peroxycitric, peroxybenzoic acid, and mixtures thereof.

28. A composition as in claim 1, wherein the peroxygen is present at from 0.05 wt % to 5.0 wt % as part of the aqueous vehicle.

29. A composition as in claim 1, wherein the peroxygen is present at from 0.1 wt % to 3.0 wt % as part of the aqueous vehicle.

30. A composition as in claim 1, wherein the peroxygen is present at from 0.1 wt % to 1.5 wt % as part of the aqueous vehicle.

31. A composition as in claim 1, wherein the peroxygen includes a peroxide.

32. A composition as in claim 31, wherein the peroxide is hydrogen peroxide.

33. A composition as in claim 31, wherein the peroxide is a metal peroxide.

34. A composition as in claim 33, wherein the metal peroxide is selected from the group consisting of sodium peroxide, magnesium peroxide, calcium peroxide, barium peroxide, and strontium peroxide, and mixtures thereof.

35. A composition as in claim 31, wherein the peroxide is a peroxyhydrate.

36. A composition as in claim 31, wherein the peroxide is generated in situ.

37. A composition as in claim 36, wherein the peroxide is hydrogen peroxide generated from sodium percarbonate.

38. A composition as in claim 1, wherein the peroxygen includes a peracid and a peroxide.

39. A composition as in claim 1, wherein the peroxygen is a peracid salt.

40. A composition as in claim 39, wherein the peracid salt is selected from the group consisting of permanganates, perborates, perchlorates, peracetates, percarbonates, persulphates, and combinations thereof.

41. A composition as in claim 1 impregnated in a fabric as a disinfectant wipe.

42. A composition as in claim 1, further comprising a thickening or gelling agent having the aqueous composition admixed therein to form a disinfectant gel.

43. A composition as in claim 1, in the form of an aerosolized disinfectant having a particle size from about 5 μ

m to about 200 μ

m.

44. A composition as in claim 1, further comprising a foaming agent to form a disinfectant foam.

45. A composition as in claim 1, formulated in a personal hygiene product selected from the group consisting of a shampoo, a soap, a gel, a cream or ointment, a toothpaste, or an oral rinse.

46. An aqueous disinfectant composition, comprising:

a) an aqueous vehicle, including;

i) water;

ii) from 0.001 wt % to 10.0 wt % of a peroxygen; and

iii) an alcohol;

b) from 0.001 ppm to 50,000 ppm by weight of a colloidal silver or alloy thereof based on the aqueous vehicle content.

47. A composition as in claim 46, wherein the disinfectant composition is substantially free of aldehydes, chlorine and bromine-containing components, iodophore-containing components, phenolic-containing components, and quaternary ammonium-containing components.

48. A composition as in claim 46, wherein the alcohol is present at from from 0.001 wt % to 40 wt %.

49. A composition as in claim 46, wherein the alcohol is present at from 0.1 wt % to 10 wt %.

50. A composition as in claim 46, wherein the alcohol is a polyhydric alcohol.

51. A composition as in claim 46, wherein the colloidal silver or alloy thereof is an alloy of the silver and ruthenium, rhodium, osmium, iridium, palladium, platinum, copper, or gold.

52. A composition as in claim 46, wherein the colloidal silver or alloy thereof has an average particle size of from 0.001 μ

m to 1.0 μ

m.

53. A composition as in claim 46, wherein the transition metal or alloy thereof is present at from 15 ppm to 1500 ppm by weight.

54. A composition as in claim 46, wherein the peroxygen is a peracid.

55. A composition as in claim 54, wherein the peracid is an aliphatic peracid or an aromatic peracid.

56. A composition as in claim 46, wherein the peroxygen is present at from 0.05 wt % to 5.0 wt % as part of the aqueous vehicle.

57. A composition as in claim 46, impregnated in a fabric as a disinfectant wipe.

58. A composition as in claim 46, further comprising a thickening or gelling agent having the aqueous composition admixed therein to form a disinfectant gel.

59. A composition as in claim 46, in the form of an aerosolized disinfectant having a particle size from about 5 μ

m to about 200 μ

m.

60. A composition as in claim 46, further comprising a foaming agent to form a disinfectant foam.

61. A composition as in claim 46, formulated in a personal hygiene product selected from the group consisting of a shampoo, a soap, a gel, a cream, an ointment, a toothpaste, or an oral rinse.

62. A method of disinfecting a surface, comprising:

contacting the surface with a disinfectant composition, comprising;

a) an aqueous vehicle, including;

i) water;

ii) from 0.001 wt % to 10.0 wt % of a peroxygen; and

iii) an alcohol;

b) from 0.001 ppm to 50,000 ppm by weight of a transition metal or alloy thereof based on the aqueous vehicle content.

63. A method as in claim 62, wherein the alcohol is present at from 0.05 wt % to 40 wt %.

64. A method as in claim 63, wherein the alcohol is present at from 0.1 wt % to 10 wt %.

65. A method as in claim 62, wherein the alcohol is a C₁-C₂₄ alcohol and is selected from the group consisting of methanol, ethanol, propanols, butanols, pentanols, and mixtures thereof.

66. A method as in claim 62, wherein the C₁-C₂₄ alcohol is a polyhydric alcohol.

67. A method as in claim 62, wherein the polyhydric alcohol is glycerol.

68. A method as in claim 62, wherein the transition metal or alloy thereof is a Group VI to Group XI transition metal or alloy selected from the group consisting of ruthenium, rhodium, osmium, iridium, palladium, platinum, copper, gold, silver, alloys thereof, and mixtures thereof.

69. A method as in claim 62, wherein the transition metal or alloy thereof is a colloidal transition metal or alloy thereof.

70. A method as in claim 62, wherein the colloidal transition metal is colloidal silver.

71. A method as in claim 62, wherein the peroxygen is a peracid selected from the group consisting of peroxyformic acid, peroxyacetic acid, peroxyoxalic acid, peroxypropanoic acid, perlactic acid, peroxybutanoic acid, peroxypentanoic acid, peroxyhexanoic acid, peroxyadipic acid, peroxycitric, peroxybenzoic acid, and mixtures thereof.

72. A method as in claim 62, wherein the peroxygen is present at from 0.05 wt % to 5.0 wt % as part of the aqueous vehicle.

73. A method as in claim 62, wherein the peroxygen is present at from 0.1 wt % to 3.0 wt % as part of the aqueous vehicle.

74. A method as in claim 62, wherein the peroxygen is present at from 0.1 wt % to 1.5 wt % as part of the aqueous vehicle.

75. A method as in claim 62, wherein the peroxygen includes a peroxide.

76. A method as in claim 62, wherein the peroxide selected from the group consisting of hydrogen peroxide, sodium peroxide, magnesium peroxide, calcium peroxide, barium peroxide, and strontium peroxide, and mixtures thereof.

77. A method as in claim 62, wherein the peroxygen includes a peracid and a peroxide.

78. A method as in claim 62, wherein the peroxygen is a peracid salt selected from the group consisting of permanganates, perborates, perchlorates, peracetates, percarbonates, persulphates, and combinations thereof.