Stent with integrated filter

• US 20070055365A1
• Filed: 04/27/2006
• Published: 03/08/2007
• Est. Priority Date: 04/28/2005
• Status: Abandoned Application

• Current Assignee: Cleveland Clinic Foundation
• Original Assignee: Cleveland Clinic Foundation
• Inventors: Greenberg, Roy, Deford, John
• Application Number:
  US11/412,465
• Publication Number:
  US 20070055365A1
• Time in Patent Office: Days
• US Class Current: 623/1.440
• CPC Class Codes: A61F 2/0105 Open ended, i.e. legs gathered only at one side
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2002/91533 characterised by the phase between adjacent bands
• CPC Class Codes: A61F 2002/91558 connected peak to peak
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2230/0069 cylindrical
• CPC Class Codes: A61F 2230/0078 hyperboloidal
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61F 2250/0039 differing in diameter

Abstract

A medical device that may be implanted intraluminally in a patient includes a stent and a filter combination. In one variation, the device includes a stent with a distal portion adapted to capture particles during the placement of the device in a stenosed region within a blood vessel. In another variation, the device includes a collapsible filter positioned within the distal lumen of the stent.

Claims

1. A vascular intervention device, comprising:

a stent; and

a filter coupled to a distal portion of said stent.

2. The vascular intervention device according to claim 1, wherein said filter comprises a plurality of pores positioned over the distal portion of said stent for filtering particles within blood flow.

3. The vascular intervention device according to claim 2, wherein said stent is comprised of a self-expanding material.

4. The vascular intervention device according to claim 1, further comprising a polymeric layer surrounding a circumferential surface of said stent, the polymeric layer having a plurality of pores in a distal end thereof.

5. The vascular intervention device according to claim 4, wherein the polymeric layer comprises ePTFE.

6. The vascular intervention device according to claim 4, wherein said polymeric layer comprises one or more materials selected from a group consisting of ePTFE urethane, silicone, or nylon, and combination thereof.

7. The vascular intervention device according to claim 4, wherein said polymeric layer further comprises a therapeutic agent.

8. The vascular intervention device according to claim 4, wherein said polymeric layer further comprises a biological material.

9. The vascular intention device according to claim 5, wherein said stent comprises nitinol.

10. The vascular intervention device according to claim 1, further comprising a polymeric layer surrounding a circumferential surface of said stent, said polymeric layer comprising a first set of pores positioned over the distal portion of said stent and a second set of pores positioned over a proximal portion of said stent, wherein said first set of pores are smaller than said second set of pores.

11. The vascular intervention device according to claim 10, wherein each of said first set of pores has a diameter from about 50 micron to about 100 micron.

12. The vascular intervention device according to claim 10, wherein each of said second set of pores has a diameter from about 20 micron to about 200 micron.

13. The vascular intervention device according to claim 10, wherein said polymeric layer comprises ePTFE.

14. The vascular intervention device according to claim 10, wherein said stent is self-expandable.

15. The vascular intervention device according to claim 10, further comprises an expansion mechanism having a portion positioned within a lumen of the stent.

16. The vascular intervention device according to claim 15, wherein the expansion mechanism comprises a balloon configured to expand the stent.

17. The vascular intervention device according to claim 1, further comprising a polymeric layer surrounding a distal circumferential surface of said stent, said polymeric layer comprising a plurality of pores.

18. The vascular intervention device according to claim 1, wherein said filter comprises a collapsible porous structure positioned over a distal opening of said stent.

19. The vascular intervention device according to claim 18, wherein said collapsible porous structure comprises a biodegradable material.

20. The vascular intervention device according to claim 18, wherein said collapsible porous structure is configured to be dismantled after the stent has been deployed within a blood vessel.

21. The vascular intervention device according to claim 1, wherein said filter is positioned over a distal opening of said stent.

22. The vascular intervention device according to claim 1, wherein said filter comprises a porous film positioned over a distal opening of said stent.

23. The vascular intervention device according to claim 1, wherein said filter comprises a cone shaped structure positioned over a distal opening of said stent.

24. The vascular intervention device according to claim 1, wherein said filter is positioned within a lumen of said stent.

25. The vascular intervention device according to claim 24, wherein said filter comprises a porous film.

26. A method of implanting a stent within a blood vessel, comprising:

inserting said stent into the blood vessel, wherein a distal portion of said stent comprises a filter; and

deploying the distal portion of said stent at a location distal of a stenosed region to capture particles breaking from said stenosed region while permitting fluids to pass through.

27. The method of implanting a stent according to claim 26, wherein the distal portion of said stent in the deploying step comprises a plurality of pores to allow blood to flow through.

28. The method according to claim 26, further comprising the step of deploying a proximal portion of said stent over said stenosed region.

29. The method according to claim 28, further comprising the step of expanding said stent and forcing at least a proximal portion of said stent against an inner wall of said blood vessel.

30. The method according to claim 29 wherein said filter comprises a polymeric layer covering at least the distal portion of said stent, wherein said polymeric layer comprises a plurality of pores, and each of said pores is at least 50 micron in diameter.

31. The method according to claim 26, wherein the distal portion of said stent in the deploying step comprises a polymeric layer covering a circumferential surface of said stent, and said polymeric film includes a plurality of pores.

32. The method according to claim 26, wherein said stent in the deploying step comprises a plurality of pores located over the distal portion of said stent forming said filter.

33. The method according to claim 26, wherein said stent in the deploying step further comprises a material woven over at least the distal portion of the stent.

34. The method according to claim 32, wherein each of said plurality of pores has a diameter between about 50 micron to about 100 micron.

35. The method according to claim 26, further comprising the step of expanding an expandable porous surface to form said filter.

36. The method according to claim 26, wherein said deploying step further comprises allowing the distal portion of said stent to expand and engage an inner wall of the blood vessel while keeping a proximal portion of said stent compressed.

37. The method according to claim 36, further comprising the step of deploying a proximal portion of said stent in said stenosed region.

38. The method according to claim 26, wherein the inserting said stent step further comprises inserting an elongated body, which houses said stent within a distal portion of said elongated body, into said blood vessel, wherein said elongated body further comprises a first mechanism for dilating a segment of the blood vessel prior to deployment of a proximal portion of said stent, and a second mechanism for deploying said stent.

39. The method according to claim 26, further comprising the step of dilating the stenosed region.

40. The method according to claim 39, further comprising the step of deploying a proximal portion of said stent.

41. The method according to claim 40, further comprising the step of expanding said stent and forcing said stent against an inner wall of the blood vessel.

42. The method according to claim 41, wherein the inserting step further comprises inserting an elongated body, which houses said stent in a distal portion of said elongated body, into the blood vessel, wherein mechanisms for accomplishing the deploying the distal portion step, the dilating step, the deploying the proximal portion step, and the expanding step, are all housed within said elongated body.

43. An implantable device comprising:

a tubular structure configured for expanding a stenosed region in a blood vessel; and

means for filtering blood flow.

44. A vascular intervention apparatus comprises:

a stent, wherein a distal portion of said stent is configured as a filter;

means for dilating a segment of a blood vessel prior to deployment of said stent; and

means for deploying said stent.