Medical treatment of breast cancer with boric acid materials

• US 20070059382A1
• Filed: 09/11/2006
• Published: 03/15/2007
• Est. Priority Date: 09/09/2005
• Status: Abandoned Application

• Current Assignee: Board of Regents Nevada System of Higher Education (State of Nevada)
• Original Assignee: Board of Regents Nevada System of Higher Education (State of Nevada)
• Inventors: Carper, Stephen, Meacham, Susan
• Application Number:
  US11/519,116
• Publication Number:
  US 20070059382A1
• Time in Patent Office: Days
• US Class Current: 424/658
• CPC Class Codes: A61K 33/22 Boron compounds

Abstract

Breast cancer cell lines selected from the group consisting of ZR-75-1 and SK-BR-3 are treated by a method comprising: identifying the presence of at least one of breast cancer cell lines ZR-75-1 and SK-BR-3 in a patient; and providing a solution of boric acid or boric acid salts to the patient in a manner that delivers boric acid or boric acid salt to breast cancer cells in the patient.

Claims

1. A method for the treatment of breast cancer cell lines selected from the group consisting of ZR-75-1 and SK-BR-3, the method comprising:

identifying the presence of at least one of breast cancer cell lines ZR-75-1 and SK-BR-3 in a patient; and

providing a solution of boric acid or boric acid salts to the patient in a manner that delivers boric acid or boric acid salt to breast cancer cells in the patient.

2. The method of claim 1 wherein the solution comprises at least 0.05 mM of boric acid or boric acid salt.

3. The method of claim 1 wherein the solution comprises at least 0.10 mM of boric acid or boric acid salt.

4. The method of claim 2 wherein the solution is delivered intravenously.

5. The method of claim 3 wherein the solution is delivered intravenously.

6. The method of claim 2 wherein the boric acid is injected to a site where breast cancer cells have been located within the patient.

7. The method of claim 3 wherein the boric acid is injected to a site where breast cancer cells have been located within the patient.

11. The method of claim 1 wherein the boric acid or boric acid salt is assisted in cell delivery by the addition to a patient of an effective amount of at least one ion transporting protein.

14. The method of claim 11 wherein the organic boron compound comprises a borane or borane salt.

8. A method for the treatment or prevention of breast cancer cell lines comprising

providing boric acid or boric acid salts to the patient in a manner that delivers boric acid or boric acid salt to breast cancer cells and the breast region of a patient.

9. The method of claim 8 wherein the method is for the treatment of breast cancer cell lines selected from identified groups previously identified as being growth reduction affected by boric and its salts and the method comprises:

identifying the presence in a patient of at least one of breast cancer cell lines of the identified groups in a patient; and

providing a solution of boric acid or boric acid salts to the patient in a manner that delivers boric acid or boric acid salt to breast cancer cells of the identified groups in the patient.

10. The method of claim 8 wherein the process is for the prevention of breast cancer cell lines and the boric acid salts are provided in solid form and orally ingested by the patient.

13. The method of claim 10 wherein the organic boron compound is assisted in cell delivery by the addition to a patient of an effective amount of at least one ion transporting protein.

12. A method for the treatment of breast cancer cell lines selected from the group consisting of ZR-75-1 and SK-BR-3, the method comprising:

identifying the presence of at least one of breast cancer cell lines ZR-75-1 and SK-BR-3 in a patient; and

providing a solution of organic boron compound to the patient in a manner that delivers the organic boron compound to breast cancer cells in the patient.