Mineralization and biological modification of biomaterial surfaces
1 Assignment
0 Petitions
Accused Products
Abstract
Disclosed are advantageous methods for patterning and/or mineralizing biomaterial surfaces. The techniques described are particularly useful for generating three-dimensional or contoured bioimplant materials with patterned surfaces or patterned, mineralized surfaces. Also provided are various methods of using the mineralized and/or patterned biomaterials in tissue engineering, such as bone tissue engineering, providing more control over ongoing biological processes, such as mineralization, growth factor release, cellular attachment and tissue growth.
-
Citations
113 Claims
-
1-95. -95. (canceled)
-
96. A method for controlling mineralization of a biomaterial surface, said process comprising the steps of:
-
a) mineralizing a first biomaterial surface, said first biomaterial having a first polymer composition b) modifying said first polymer composition of (a) to prepare a second biomaterial having a second polymer composition;
wherein said second polymer composition provides said second biomaterial with a surface that will modify mineralizing of said second biomaterial surface compared to said first biomaterial surface to a desired extent using the same mineralizing process. - View Dependent Claims (97, 98, 99, 100, 101, 102, 103, 104, 105)
-
-
106. A method for controlling mineralization of a biomaterial surface, said process comprising the steps of:
-
a) mineralizing a first biomaterial surface, said first biomaterial having a first set of surface properties b) modifying said first set of surface properties of (a) to prepare a second biomaterial having a second set of surface property;
wherein said second set of surface properties provides said second biomaterial with a surface that will modify mineralizing of said second biomaterial surface compared to said first biomaterial surface to a desired extent using the same mineralizing process. - View Dependent Claims (107, 108, 109, 110, 111, 112, 113)
-
Specification