Method of using spinal cord stimulation to treat neurological disorders or conditions

• US 20070060954A1
• Filed: 02/27/2006
• Published: 03/15/2007
• Est. Priority Date: 02/25/2005
• Status: Abandoned Application

• Current Assignee: Advanced Neuromodulation Systems Incorporated (Abbott Laboratories)
• Original Assignee: Advanced Neuromodulation Systems Incorporated (Abbott Laboratories)
• Inventors: Cameron, Tracy, Chavez, Christopher
• Application Number:
  US11/363,383
• Publication Number:
  US 20070060954A1
• Time in Patent Office: Days
• US Class Current: 607/2
• CPC Class Codes: A61N 1/0553 Paddle shaped electrodes, e.g. for laminotomy
• CPC Class Codes: A61N 1/36021 for treatment of pain
• CPC Class Codes: A61N 1/3605 Implantable neurostimulators for stimulating central or peripheral nerve system
• CPC Class Codes: A61N 1/36075 Headache or migraine
• CPC Class Codes: A61N 1/36103 Neuro-rehabilitation; Repair or reorganisation of neural tissue, e.g. after stroke
• CPC Class Codes: A61N 1/36117 for treating hypertension

Abstract

The present invention involves methods and systems for using electrical stimulation to treat neurological disorders. More particularly, the method comprises surgically implanting an electrical stimulation lead that is in communication with spinal nervous tissue associated with a first, second, or third cervical vertebral segment to result in spinal nervous tissue stimulation, thus treating a wide variety of neurological disorders.

Claims

1. A method of treating a patient with a neurological disorder or condition comprising the steps of:

surgically implanting in the patient a stimulation system in communication with spinal nervous tissue at one or more areas associated with the first, second, or third cervical vertebral segment;

stimulating the spinal nervous tissue by operating the system; and

treating the neurological disorder or condition with the stimulation.

2. The method of claim 1, wherein the stimulating comprises electrical stimulation.

3. The method of claim 1, wherein the stimulating comprises chemical stimulation.

4. The method of claim 1, wherein the neurological disorder or condition is further defined as an affective disorder.

5. The method of claim 1, wherein the neurological disorder or condition is further defined as a mood disorder.

6. The method of claim 1, wherein the neurological disorder or condition is further defined as a sleep disorder.

7. The method of claim 1, wherein the neurological disorder or condition is further defined as a motor disorder.

8. The method of claim 7, wherein the motor disorder is selected from the group consisting of comprise tremor, dystonia, and seizure.

9. The method of claim 1, wherein the neurological disorder or condition is further defined as epilepsy.

10. The method of claim 1, wherein the neurological disorder or condition is further defined as Parkinson'"'"'s Disease.

11. The method of claim 1, wherein the neurological disorder is a decreased in cognitive functioning.

12. The method of claim 11, wherein the decreased cognitive functioning comprises one or more impaired memory, reduced attention and concentration, and reduced information processing capacity.

13. The method of claim 1, wherein the neurological disorder is selected from the group consisting of intractable nausea, chronic fatigue, and migraine headaches.

14. The method of claim 1, wherein the spinal nervous tissue is associated with the first cervical vertebral segment.

15. The method of claim 1, wherein the spinal nervous tissue is associated with the second vertebral segment.

16. The method of claim 1, wherein the spinal nervous tissue is associated with the third vertebral segment.

17. The method of claim 1, wherein the system comprises an electrode.

18. The method of claim 1, wherein the system allows the patient to control the frequency of stimulation.

19. The method of claim 1, wherein the stimulation is noncontinuous.

20. The method of claim 1, further comprising the step of assessing the neurological disease or condition in the patient after the stimulation.

21. A method of increasing blood flow to the brain comprising the steps of:

surgically implanting a stimulation system in communication with spinal nervous tissue at one or more areas associated with the first, second, or third cervical vertebral segment;

operating the system to stimulate the spinal nervous tissue; and

increasing blood flow to the brain.

22. The method of claim 22, further comprising the step of assessing the blood flow to the brain.

23. A method of treating hypertension in a patient comprising the steps of:

surgically implanting in the patient a stimulation system in communication with spinal nervous tissue at one or more areas associated with the first, second, or third cervical vertebral segment;

operating the system to stimulate the spinal nervous tissue; and

treating hypertension in the patient.

24. A method of treating a migraine headache in a patient comprising the steps of:

surgically implanting in the patient a stimulation system in communication with spinal nervous tissue at one or more areas associated with the first, second, or third cervical vertebral segment;

operating the system to stimulate the spinal nervous tissue; and

treating the migraine headache in the patient.

25. A method of treating a neurological disorder and/or condition comprising the steps of:

surgically implanting at least one electrode that is in communication with spinal nervous tissue at one or more areas associated with the first, second, or third cervical vertebral segment;

coupling the electrode to a pulse generating source; and

generating an electrical signal with the pulse generating source wherein said signal electrically stimulates the spinal nervous tissue, thereby treating the neurological disorder and/or condition.

26. The method of claim 25 further comprising the steps of:

surgically implanting a catheter having a proximal end coupled to a pump and a discharge portion for infusing a dosage of a pharmaceutical, wherein after implantation the discharge portion of the catheter is in communication with the spinal nervous tissue; and

operating the pump to discharge the pharmaceutical through the discharge portion of the catheter into the spinal nervous tissue thereby treating the neurological disorder and/or condition.

27. The method of claim 25, wherein the stimulation results in modulation of blood flow to the brain.

28. The method of claim 25, wherein the neurological disorder and/or condition is selected from the group consisting of Developmental Disabilities, Pervasive Developmental Disorders and Autistic Spectrum Disorders, nonverbal learning disabilities, Demyleinating Diseases, delirium and dementia, affective disorder, movement disorders, ataxic disorders, substance abuse related disorders, sexual dysfunctions, eating disorders, anxiety and obsessive compulsive disorder syndromes, impulse control disorders, personality disorders, and Chiari I malformation.

29. A stimulation system for treating a neurological disorder and/or condition comprising:

at least two electrodes operatively connected in a single unit to a signal generator, the electrodes in communication with spinal nervous tissue at one or more areas associated with the first, second, or third cervical vertebral segment, thereby stimulating the spinal nervous tissue, and treating the neurological disorder and/or condition.

30. A stimulation system for treating a neurological disorder and/or condition comprising:

at least one electrode in communication with spinal nervous tissue at one or more areas associated with the first, second, or third cervical vertebral segment; and

a pulse generation source operatively connected to at least one, thereby stimulating the spinal nervous tissue, and treating the neurological disorder and/or condition.

31. The system of claim 30, wherein the pulse generation source an electrical signal.

32. A system for treating subjects with neurological disorders and/or conditions comprising:

at least one electrode that is implanted into the subject'"'"'s spinal nervous tissue, the least one electrode is in communication with spinal nervous tissue at one or more areas associated with the first, second, or third cervical vertebral segment;

a pulse generation source that generates signals for transmission to the at least one electrode resulting in delivery of electrical signals to the spinal nervous tissue thereby treating the neurological disorder and/or conditions.

33. The system of claim 32, wherein the pulse generation source is implanted in the subject'"'"'s body.