Infusion Pump With Closed Loop Control and Algorithm

• US 20070062251A1
• Filed: 09/18/2006
• Published: 03/22/2007
• Est. Priority Date: 09/19/2005
• Status: Abandoned Application

• Current Assignee: Lifescan Incorporated (Duv Holding Corporation)
• Original Assignee: Lifescan Incorporated (Duv Holding Corporation)
• Inventors: Anex, Deon
• Application Number:
  US11/532,598
• Publication Number:
  US 20070062251A1
• Time in Patent Office: Days
• US Class Current: 73/1.360
• CPC Class Codes: A61M 2005/14513 with secondary fluid driving or regulating the infusion
• CPC Class Codes: A61M 2205/3317 Electromagnetic, inductive or dielectric measuring means
• CPC Class Codes: A61M 2205/702 automatically during use
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence

Abstract

Systems and methods of controlling the flow of fluid from infusion pumps, such as pumps utilizing an electrokinetic engine, are discussed. In particular, a closed loop control technique can be utilized to regulate movement of a non-mechanically-driven moveable partition, which can be used to drive the flow of an infusion fluid. For example, one or more fluid shot amounts can be delivered by the infusion pump. One or more measured amounts can be determined for the fluid shot amount(s). An average measured amount can be calculated from the measured amounts, and a correction factor can be calculated using the average measured amount and an expected shot amount. Subsequently, a fluid shot amount can be delivered base upon the correction factor. Variations of this method, and systems for implementing the method, or portions thereof, are also discussed.

Claims

1. A method of controlling fluid delivery from an infusion pump having a non-mechanically-driven moveable partition, comprising:

delivering at least one fluid shot amount from the infusion pump;

determining at least one measured amount for the at least one fluid shot amount;

calculating an average measured amount using the at least one measured amount;

calculating a correction factor using the average measured amount and an expected amount; and

adjusting subsequent fluid delivery from the infusion pump based at least in part on the correction factor.

2. The method of claim 1, wherein delivering the at least one fluid shot amount includes delivering a plurality of fluid shot amounts, and adjusting subsequent fluid delivery includes delivering a subsequent fluid shot amount based at least in part on the correction factor.

3. The method of claim 2, wherein determining at least one measured amount includes determining a measured amount for each of the plurality of fluid shot amounts.

4. The method of claim 1, wherein calculating the average measured amount includes using at least one weighting factor to weight at least one measured amount.

5. The method of claim 4, wherein calculating the average measured amount includes using at least one weighting factor to more heavily weight at least one later measured amount relative to at least one earlier measured amount.

6. The method of claim 1, wherein calculating the average measured amount includes using a previous average measured amount to calculate the average measured amount.

7. The method of claim 6, wherein calculating the average measured amount includes using the following relationship

${\mathrm{average}}_n=\frac{(\varepsilon }{}$

×

amt last , meas ) + average n - 1 ɛ

+ 1

wherein;

n is a number equal to a selected number of measured amounts;

average_n is the average measured amount calculated using the last n measured amounts;

ε

is a designated weighting factor;

amt_last,meas is the last measured amount; and

average<sub>n−

1</sub> is the previous average measured amount calculated using all n measured amounts except for the last measured amount.

8. The method of claim 1, wherein calculating the correction factor includes relating the correction factor to a difference between the average measured amount and the expected amount.

9. The method of claim 8, wherein calculating the correction factor further includes relating the correction factor to a product of a proportionality factor and the difference between the average measured amount and the expected amount.

10. The method of claim 2, wherein delivering the subsequent fluid shot amount includes adjusting operation of the infusion pump using the correction factor to deliver a subsequent shot amount.

11. The method of claim 10, wherein adjusting operation includes altering a shot duration corresponding with the subsequent fluid shot amount.

12. The method of claim 1, wherein the infusion pump is an electrokinetic infusion pump.

13. The method of claim 12, wherein adjusting subsequent fluid delivery includes using the correction factor to control at least one of voltage and current applied between electrodes of the electrokinetic infusion pump.

14. The method of claim 1, wherein the step of determining at least one measured amount includes determining a position of the movable partition in the infusion pump.

15. A system for controlling fluid flow from an infusion pump having a non-mechanically-driven moveable partition, comprising:

a position detector coupled to the movable partition for driving fluid from the infusion pump, the position detector configured to emit a signal that identifies the position of the movable partition; and

a controller coupled to the position detector and the movable partition, the controller configured to control delivery of fluid from the infusion pump based at least in part upon an expected amount and an average measured amount calculated from at least one previously measured amount.

16. The system of claim 15, wherein the controller is configured to control delivery of a fluid shot amount from the infusion pump, and the average measured amount is calculated from a plurality of previously measured amounts.

17. The system of claim 16, wherein the controller is configured to obtain each of the plurality of previously measured amounts based at least in part upon a corresponding signal received from the position detector.

18. The system of claim 15, wherein the position detector comprises at least one of a magnetic sensor and an optical sensor.

19. The system of claim 18, wherein the position detector comprises at least one magnetic sensor coupled to a housing of the infusion pump, and at least one magnet coupled to the movable partition.

20. The system of claim 15, wherein the controller is configured to calculate the average measured amount by applying at least one weighting factor to at least one previously measured amount.

21. The system of claim 20, wherein the controller is configured to calculate the average measured amount based at least in part on a previously calculated average measured amount.

22. The system of claim 21, wherein the controller is configured to calculate the average measured amount by applying the following relationship:

${\mathrm{average}}_n=\frac{\left(\mathrm{\varepsilon <br><br>}\times <br><br>{\mathrm{amt}}_{\mathrm{last},\mathrm{meas}}\right)+{\mathrm{average}}_{n-1}}{\mathrm{\varepsilon <br><br>}+1}$

wherein;

n is a number equal to the plurality of previously measured amounts;

average_n is the average measured amount using n previously measured amounts;

ε

is a designated weighting factor;

amt_last,meas is a last measured amount; and

average<sub>n−

1</sub> is the average measured amount using all n previously measured amounts except for the last measured amount.

23. The system of claim 15, wherein the controller is configured to control fluid delivery based in part on at least a designated fraction of a difference between the average measured amount and the expected amount.

24. The system of claim 15, wherein the controller is coupled to a power source for driving the infusion pump, the controller configured to control fluid delivery by adjusting power delivered by the power source.

25. The system of claim 15, wherein the infusion pump is an electrokinetic infusion pump.

26. The system of claim 25, wherein the controller is configured to control at least one of voltage applied between electrodes of the electrokinetic infusion pump and current flow between electrodes of the electrokinetic infusion pump.

27. The system of claim 15, wherein the controller is configured to control the delivery of a plurality of fluid shot amounts, and a shot duration associated with each fluid shot amount.