Compositions and methods for the augmentation and repair of defects in tissue
First Claim
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1. A composition comprising an in vitro preparation of autologous cells and an immunogenic cell-absorbable protein immunogenic relative to an individual that contributed the autologous cells.
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Abstract
Compositions and methods of treating a defect in a patient are disclosed, including expanding a culture of autologous cells in vitro to form cultured cells, collecting the cultured cells for introduction into the patient, and depositing the cultured cells with ancillary proteins.
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Citations
51 Claims
- 1. A composition comprising an in vitro preparation of autologous cells and an immunogenic cell-absorbable protein immunogenic relative to an individual that contributed the autologous cells.
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16. A method of treating a defect in a patient comprising:
expanding a culture of autologous cells in vitro to form cultured cells, collecting the cultured cells for introduction into the patient, and depositing the cultured cells with a serum-derived protein at or near the defect in the patient. - View Dependent Claims (17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36)
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37. A method of treating a defect in a patient comprising:
expanding a culture of autologous cells in vitro, collecting the cells for introduction into the patient, incubating the cells with an effective amount of an immunogenic cell-absorbable protein, and depositing the cells at or near the defect in the patient to repair or augment a tissue at or near the defect. - View Dependent Claims (38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51)
Specification