Methods and compositions for antimicrobial surfaces

• US 20070065475A1
• Filed: 11/15/2006
• Published: 03/22/2007
• Est. Priority Date: 02/07/2005
• Status: Active Grant

• Current Assignee: Termpro LLC
• Original Assignee: Sishield Technologies, Inc.
• Inventors: Elfersy, Jacques
• Granted Patent: US 8,999,363 B2
• Time in Patent Office: Days
• US Class Current: 424/405
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 25/08 containing solids as carriers or diluents
• CPC Class Codes: A01N 33/12 Quaternary ammonium compounds
• CPC Class Codes: A01N 55/00 Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur containing organo-phosphorus compounds A01N57/00

Abstract

The present invention comprises methods and compositions for treating solid surfaces having antimicrobial and biocidal properties. Such surfaces are capable of controlling or killing a broad spectrum of biological agents, including viruses, bacteria and other microbial agents in solids, liquids or gases that subsequently contact the treated surface.

Claims

1. An antimicrobial composition, comprising, perlite coated with a composition of an organosilane quaternary compound and a quaternary ammonium compound, wherein the quaternary ammonium compound is not an organosilane quaternary compound.

2. The composition of claim 1, wherein the organosilane quaternary compound is a compound having formula R_nSiX_(4-n), wherein (1) R is, independently, an alkene group, an alkyl group, or an alkyne group, and (2) X is, independently, an alkoxy group;

and wherein each of the alkene group, the alkyl group, the alkyne group, and the alkoxy group optionally comprises an amino, a chloro, an epoxy, or a mercapto substituent.

3. The composition of claim 2, wherein the organosilane quaternary compound is selected from the group consisting of 3-trimethoxysilyl propyltetradecyldimethyl ammonium chloride, 3-(trimethoxysilyl)propyldimethyloctadecylammoniumcholide, 3-(trimethoxysilyl)propyldimethyl-hexadecylammoniumchloride, 3-trimethoxysilyl propyldidecylmethyl ammonium chloride, and 3-trihydroxysilyl propyloctadecyl ammonium chloride.

4. The composition of claim 1, wherein the quaternary ammonium compound comprises at least one compound selected from the group consisting of mono-long-chain, tri-short-chain, tetraalkyl ammonium compounds;

di-long-chain, di-short-chain, tetraalkyl ammonium compounds; and

trialkyl, mono-benzyl ammonium compounds.

5. The composition of claim 1, wherein the composition further comprises one or more of an oxidizing agent, a chelating agent, or a stabilizing agent.

6. The composition of claim 5, wherein the oxidizing agent is hydrogen peroxide.

7. The composition of claim 5, wherein the chelating agent is ethylenediaminetetraacetic acid (EDTA) or a salt thereof.

8. The aqueous composition of claim 5, wherein the stabilizing agent is propylene carbonate, glycol ether, a polyol, or sucrose.

9. A method of rendering perlite antimicrobial comprising, contacting perlite with an aqueous composition, wherein the aqueous composition comprises an organosilane quaternary compound and a quaternary ammonium compound, and wherein the quaternary ammonium compound is not an organosilane quaternary compound.

10. The method of claim 9, wherein the organosilane quaternary compound is a compound having formula R_nSiX_(4-n), wherein (1) R is, independently, an alkene group, an alkyl group, or an alkyne group, and (2) X is, independently, an alkoxy group;

and wherein each of the alkene group, the alkyl group, the alkyne group, and the alkoxy group optionally comprises an amino, a chloro, an epoxy, or a mercapto substituent.

11. The method of claim 10, wherein the organosilane quaternary compound is selected from the group consisting of 3-trimethoxysilyl propyltetradecyldimethyl ammonium chloride, 3-trimethoxysilyl propyldidecylmethyl ammonium chloride, and 3-trihydroxysilyl propyloctadecyl ammonium chloride.

12. The method of claim 9, wherein the quaternary ammonium compound comprises at least one compound selected from the group consisting of mono-long-chain, tri-short-chain, tetraalkyl ammonium compounds;

di-long-chain, di-short-chain, tetraalkyl ammonium compounds; and

trialkyl, mono-benzyl ammonium compounds.

13. The composition of claim 9, wherein the composition further comprises one or more of an oxidizing agent, a chelating agent, or a stabilizing agent.

14. The composition of claim 13, wherein the oxidizing agent is hydrogen peroxide.

15. The composition of claim 13, wherein the chelating agent is ethylenediaminetetraacetic acid (EDTA) or a salt thereof.

16. The aqueous composition of claim 13, wherein the stabilizing agent is propylene carbonate, glycol ether, a polyol, or sucrose.

17. A method of removing a portion of microbes present in a gas, liquid or solid, comprising contacting a gas, liquid or solid with a composition having antimicrobial activity comprising perlite coated with a composition comprising an organosilane quaternary compound and a quaternary ammonium compound, and wherein the quaternary ammonium compound is not an organosilane quaternary compound.

18. The method of claim 17, wherein the organosilane quaternary compound is a compound having formula R_nSiX_(4-n), wherein (1) R is, independently, an alkene group, an alkyl group, or an alkyne group, and (2) X is, independently, an alkoxy group;

and wherein each of the alkene group, the alkyl group, the alkyne group, and the alkoxy group optionally comprises an amino, a chloro, an epoxy, or a mercapto substituent.

19. The method of claim 18, wherein the organosilane quaternary compound is 3-trimethoxysilyl propyltetradecyldimethyl ammonium chloride, 3-trimethoxysilyl propyldidecylmethyl ammonium chloride, or 3-trihydroxysilyl propyloctadecyl ammonium chloride.

20. The method of claim 17, wherein the composition having antimicrobial activity further comprises one or more of an oxidizing agent, a chelating agent or a stabilizing agent.