Isoxazoline-substituted benzamide compound and pesticide

• US 20070066617A1
• Filed: 09/05/2006
• Published: 03/22/2007
• Est. Priority Date: 03/05/2004
• Status: Active Grant

• Current Assignee: Nissan Chemical Corporation
• Original Assignee: Nissan Chemical Industries Limited (Shin-Etsu Chemical Company Limited)
• Inventors: Yaosaka, Manabu, Mizukoshi, Takashi, Mita, Takeshi, Komoda, Mitsuaki, Kikuchi, Takamasa
• Granted Patent: US 7,662,972 B2
• Time in Patent Office: Days
• US Class Current: 514/241
• CPC Class Codes: A01N 43/80 five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
• CPC Class Codes: A61K 31/421 1,3-Oxazoles, e.g. pemoline, trimethadione
• CPC Class Codes: A61K 9/0053 Mouth and digestive tract, i.e. intraoral and peroral administration rectal administration A61K9/0031
• CPC Class Codes: A61P 33/04 Amoebicides
• CPC Class Codes: A61P 33/06 Antimalarials
• CPC Class Codes: A61P 33/10 Anthelmintics
• CPC Class Codes: A61P 33/12 Schistosomicides
• CPC Class Codes: A61P 33/14 Ectoparasiticides, e.g. scabicides
• CPC Class Codes: C07C 205/11 having nitro groups bound to carbon atoms of six-membered aromatic rings
• CPC Class Codes: C07C 205/12 the six-membered aromatic ring or a condensed ring system containing that ring being substituted by halogen atoms
• CPC Class Codes: C07C 211/52 the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
• CPC Class Codes: C07C 25/02 Monocyclic aromatic halogenated hydrocarbons
• CPC Class Codes: C07C 25/06 Monochloro-benzene
• CPC Class Codes: C07C 25/08 Dichloro-benzenes
• CPC Class Codes: C07C 25/13 containing fluorine
• CPC Class Codes: C07C 25/24 Halogenated aromatic hydrocarbons with unsaturated side chains
• CPC Class Codes: C07C 251/48 with the carbon atom of at least one of the oxyimino groups bound to a carbon atom of a six-membered aromatic ring
• CPC Class Codes: C07C 255/29 containing cyano groups and acylated amino groups bound to the carbon skeleton
• CPC Class Codes: C07C 255/50 to carbon atoms of non-condensed six-membered aromatic rings
• CPC Class Codes: C07C 255/60 at least one of the singly-bound nitrogen atoms being acylated
• CPC Class Codes: C07C 281/02 : Compounds containing any of the groups , e.g. carbazates
• CPC Class Codes: C07C 323/09 : having sulfur atoms of thio groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
• CPC Class Codes: C07C 43/1742 : with halogen atoms bound to the aromatic rings
• CPC Class Codes: C07C 43/1745 : having more than one ether bound
• CPC Class Codes: C07D 261/04 : having one double bond between ring members or between a ring member and a non-ring member
• CPC Class Codes: C07D 261/16 : Benzene-sulfonamido isoxazoles
• CPC Class Codes: C07D 413/04 : directly linked by a ring-member-to-ring-member bond
• CPC Class Codes: C07D 413/06 : linked by a carbon chain containing only aliphatic carbon atoms
• CPC Class Codes: C07D 413/12 : linked by a chain containing hetero atoms as chain links
• CPC Class Codes: C07D 413/14 : containing three or more hetero rings
• CPC Class Codes: C07D 417/06 : linked by a carbon chain containing only aliphatic carbon atoms
• CPC Class Codes: C07D 417/12 : linked by a chain containing hetero atoms as chain links
• CPC Class Codes: C07F 7/0812 : comprising a heterocyclic ring

Abstract

An isoxazoline-substituted benzamide compound of formula (1) or a salt thereof:
wherein A¹, A² and A³ independently of one another are carbon atom or nitrogen atom, G is benzene ring, etc., X is halogen atom, C₁-C₆haloalkyl, etc., Y is halogen atm, C₁-C₆alkyl, etc., R¹ is C₁-C₁₂alkyl arbitrarily substituted with R¹⁶, C₃-C₂alkenyl, arbitrarily substituted with R¹⁶ is oxygen atom or sulfur atom, —N(R²⁰)R¹⁹, etc., R² is hydrogen atom, C₁-C₄alkoxy C₁-C₆alkyl, etc., R³ is C₁-C₆haloalkyl, etc., R¹⁶ is halogen atom, cyano, phenyl substituted with (Z)_p1, D-1 to D-60, E-1 to E-49, etc., R¹⁹ is phenyl, phenyl substituted with (Z)_p1, etc., R²⁰ is hydrogen atom, C₁-C₆alkyl, etc., Z is halogen atom, nitro, C₁-C₄alkoxy, etc., D-1 to D-60 are 5- or 6-membered aromatic heterocyclic rings, E-1 to E-49 are 5- or 6-membered saturated heterocyclic rings, m is an integer of 0 to 5, n is an integer of 0 to 4, p1 is an integer of 1 to 5. The pesticide containing these compounds.

Claims

1. An isoxazoline-substituted benzamide compound of formula (1) or a salt thereof:

2. The isoxazoline-substituted benzamide compound or the salt thereof according to claim 1, wherein

G is an aromatic 6-membered ring shown in any one of G-1 to G-10 or an aromatic 5-membered ring shown in any one of G-11 to G-25

X is halogen atom, cyano, nitro, —

SF₅, C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R⁴, C₃-C₈cycloalkyl, C₃-C₈cycloalkyl arbitrarily substituted with R⁴, C₂-C₆alkenyl, C₂-C₆alkenyl arbitrarily substituted with R⁴, C₂-C₆alkynyl, C₂-C₆alkynyl arbitrarily substituted with R⁴, —

OH, —

OR⁵, —

SO₂R⁵, —

S(O)_rR⁵, —

C(O)OR⁹, —

C(O)SR⁹, —

C(O)NHR¹⁰, —

C(O)N(R¹⁰)R⁹, —

C(S)OR⁹, —

C(S)SR⁹, —

C(S)NHR¹⁰, —

C(S)N(R¹⁰)R⁹, —

CH═

NOR¹¹, —

C(R⁹)═

NOR¹¹, —

S(O)₂NHR¹⁰, —

S(O)₂N(R¹⁰)R⁹, —

Si(R¹³)(R¹⁴)R¹², phenyl, phenyl substituted with (Z)_p1, D-1 to D-60 or E-1 to E-49, when m is an integer of 2 or more, each X may be identical with or different from each other, further, when two Xs are adjacent, the adjacent two Xs may form 5-membered or 6-membered ring together with carbon atoms to which the two Xs are bonded by forming —

CH₂CH₂CH₂—

, —

CH₂CH₂O—

, —

CH₂OCH₂—

, —

OCH₂O—

, —

CH₂CH₂S—

, —

CH₂SCH₂—

, —

CH₂CH₂CH₂CH₂—

, —

CH₂CH₂CH₂O—

, —

CH₂CH₂OCH₂—

, —

CH₂OCH₂O—

, —

OCH₂CH₂O—

, —

OCH₂CH₂S—

or —

CH═

CHCH═

CH—

, in this case, hydrogen atoms bonded to each carbon atom forming the ring may be arbitrarily substituted with halogen atom, C₁-C₄alkyl or C₁-C₄haloalkyl,

Y is halogen atom, cyano, nitro, C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R⁴, —

OR⁵, —

OSO₂R⁵, S(O)_rR⁵, —

NHR⁷, —

N(R⁷)R⁶, —

N═

CHOR⁸, —

N═

C(R⁹)OR⁸, —

C(O)NHR¹⁰, —

C(O)N(R¹⁰)R⁹, —

C(S)NHR¹⁰, —

C(S)N(R¹⁰)R⁹, phenyl, phenyl substituted with (Z)_p1, D-1 to D-24, D-30 to D-38, D-43 to D-52 or D-53, when n is an integer of 2 or more, each Y may be identical with or different from each other,

further, when two Ys are adjacent, the adjacent two Ys may form 5-membered or 6-membered ring together with carbon atoms to which the two Ys are bonded by forming —

CH₂CH₂CH₂—

, —

CH₂CH₂O—

, —

CH₂OCH₂—

, —

OCH₂O—

, —

CH₂CH₂CH₂CH₂—

, —

CH₂CH₂CH₂O—

, —

CH₂CH₂OCH₂—

, —

CH₂OCH₂O—

, —

OCH₂CH₂O—

, —

OCH═

N—

or —

SCH═

N—

, in this case, hydrogen atoms bonded to each carbon atom forming the ring may be arbitrarily substituted with halogen atom, C₁-C₄alkyl or C₁-C₄haloalkyl,

R¹ is C₁-C₈alkyl, C₁-C₈alkyl arbitrarily substituted with R¹⁶, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, C₃-C₈alkenyl, C₃-C₈haloalkenyl, phenyl C₃-C₆alkenyl, phenyl C₃-C₆alkenyl substituted with (Z)_p1, C₃-C₈alkynyl, C₃-C₈haloalkynyl, phenyl C₃-C₆alkynyl, phenyl C₃-C₆alkynyl substituted with (Z)_p1, C₁-C₈alkoxy, —

N(R²⁰)R¹⁹, —

N═

CHR^19b, —

N═

C(R^19b)R^19a, —

C(O)N(R¹⁰)R⁹, —

C(S)N(R¹⁰)R⁹, —

C(═

NR¹¹)OR⁹, —

C(═

NR¹¹)SR⁹, —

C(═

NR¹¹)N(R¹⁰)R⁹, phenyl, phenyl substituted with (Z)_p1, D-1 to D-4, D-6 to D-18, D-21 to D-23, D-26 to D-40, D-42, D-45 to D-58, E-4 to E-9, E-23 to E-28, E-30, E-31, E-34 or E-45,

R² is hydrogen atom, C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄haloalkoxy C₁-C₄alkyl, benzyloxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, C₁-C₄haloalkylthio C₁-C₄alkyl, C₁-C₄alkylsulfonyl C₁-C₄alkyl, C₁-C₄haloalkylsulfonyl C₁-C₄alkyl, phenylthio C₁-C₄alkyl, phenylthio C₁-C₄alkyl substituted with (Z)_p1, cyano C₁-C₆alkyl, nitro C₁-C₆alkyl, C₁-C₄alkylcarbonyl C₁-C₄alkyl, C₁-C₄alkoxycarbony C₁-C₄alkyl, C₃-C₆cycloalkyl, C₃-C₆alkenyl, C₃-C₆haloalkenyl, C₃-C₆alkynyl, —

SR⁹, —

S(O)₂R⁹, —

SN(R¹⁸)R¹⁷, —

OH, —

OR¹⁹, —

NHR²⁰, —

N(R²⁰)R¹⁹, —

N═

CHR^19b, —

N═

C(R^19b)R^19a, —

C(O)R⁹, —

C(O)OR⁹, —

C(O)SR⁹, —

C(S)OR⁹ or —

C(S)SR⁹,

or R¹ and R² together form ═

C(R^2a)R^1a, and further R¹ and R² together may form 3- to 7-membered ring together with the nitrogen atom bonding them by forming C₂ to C₆ alkylene chain, in this case, the alkylene chain may contain one oxygen atom, sulfur atom or nitrogen atom, and may be arbitrarily substituted with C₁-C₆alkyl, formyl, C₁-C₆alkylcarbonyl or C₁-C₆alkoxycarbonyl,

R^1a and R^2a together may form 5- or 6-membered ring together with the carbon atom bonding them by forming C₄ or C₅ alkylene chain or C₄ or C₅ alkenylene chain, in this case, the alkylene chain and the alkenylene chain may contain one to three oxygen atoms, sulfur atoms or nitrogen atoms, and may be arbitrarily substituted with halogen atom or C₁-C₆alkyl,

R³ is cyano, C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R⁴, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, C₃-C₆alkenyl, C₃-C₆haloalkenyl, C₃-C₆alkynyl, C₃-C₆haloalkynyl, —

OR⁵, —

S(O)_rR⁵, —

N(R¹⁰)R⁹, —

C(O)OR⁹, —

C(O)SR⁹, —

C(O)NHR¹⁰, —

C(O)N(R¹⁰)R⁹, —

C(S)OR⁹, —

C(S)SR⁹, —

C(S)NHR¹⁰, —

C(S)N(R¹⁰)R⁹, —

CH═

NOR¹¹, —

C(R⁹)═

NOR¹¹, —

Si(R¹³)(R¹⁴)R¹², phenyl, phenyl substituted with (Z)_p1, D-1 to D-4, D-8- to D-13, D-15 to D-23, D-25 to D-37, D-39, D-40, D-42, D-45 to D-60 or E-4 to E-7, E-23 to E27 or E-28,

R⁴ is halogen atom, cyano, C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, —

OH, —

OR⁵, —

S(O)_rR⁵, —

N(R¹⁰)R⁹, —

N(R¹⁰)C(O)R⁹, —

N(R¹⁰)C(O)OR⁹, —

N(R¹⁰)C(O)SR⁹, —

N(R¹⁰)C(S)OR⁹, —

N(R¹⁰)C(S)SR⁹, —

N(R¹⁰)S(O)₂R⁹, —

Si(R¹³)(R¹⁴)R¹², phenyl, phenyl substituted with (Z)_p1, D-1 to D-5, D-8 to D-38, D-41, D-43, D-44, D-47 to D-52 or D-53,

R⁵ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₁-C₃haloalkoxy C₁-C₃haloalkyl, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, C₂-C₆alkenyl, C₂-C₆haloalkenyl, C₃-C₆alkynyl, C₃-C₆haloalkynyl, phenyl, phenyl substituted with (Z)_p1, D-1 to D-4, D-7, D-9, D-15 to D-23, D-30 to D-35, D-47 to D-53, E-3 to E-9, E-23 to E-27 or E-28,

R⁶ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, —

S(O)₂R⁹, —

CHO, —

C(O)R⁹, —

C(O)OR⁹, —

C(O)SR⁹, —

C(S)OR⁹ or —

C(S)SR⁹,

R⁷ is hydrogen atom, C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆alkenyl or C₃-C₆alkynyl,

R⁸ is C₁-C₆alkyl,

R⁹ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, C₁-C₆alkoxy C₁-C₄alkyl, C₁-C₆alkylthio C₁-C₄alkyl, cyano C₁-C₆alkyl, phenyl C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, C₃-C₆alkenyl, C₃-C₆haloalkenyl, C₃-C₆alkynyl, C₃-C₆haloalkynyl, phenyl, phenyl substituted with (Z)_p1, D-1 to D-4, D-6 to D-35, D-38, D-47 to D-54 or D-55,

R¹⁰ is hydrogen atom or C₁-C₆alkyl, or R¹⁰ together with R⁹ may form 5- to 7-membered ring with the nitrogen atom bonding them by forming C₄-C₆alkylene chain, in this case, the alkylene chain may contain oxygen atom or sulfur atom,

R¹¹ is C₁-C₆alkyl, C₁-C₆haloalkyl, phenyl C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1, phenyl or phenyl substituted with (Z)_p1, or R¹¹ together with R⁹ may form 5- or 6-membered ring with the atom bonding them by forming C₂-C₃alkylene chain, in this case, the alkylene chain may be arbitrarily substituted with C₁-C₆alkyl,

R¹² is C₁-C₆alkyl, phenyl or phenyl substituted with (Z)_p1,

R¹³ and R¹⁴ independently of each other are C₁-C₆alkyl,

R¹⁵ is C₁-C₆alkyl, C₁-C₆haloalkyl, phenyl C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1, phenyl or phenyl substituted with (Z)_p1,

R¹⁶ is halogen atom, cyano, C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, —

OR²⁵, —

N(R²⁶)R²⁵, —

SH, —

S(O)_rR²⁷, —

SO₂NHR²⁹, —

SO₂N(R²⁹)R²⁸, —

CHO, —

C(O)R²⁸, —

C(O)OR²⁸, —

C(O)NHR²⁹, —

C(O)N(R²⁹)R²⁸, —

C(O)N(R²⁹)OR²⁸, —

C(S)NHR²⁹, —

C(S)N(R²⁹)R²⁸, —

C(R³¹)═

NOH, —

C(R³¹)═

NOR³⁰, —

C(═

NR³¹)OR³⁰, —

C(═

NR³¹)SR³⁰, —

C(═

NR³¹)N(R²⁹)R³⁰, —

C(═

NOR³¹)NHR²⁹, —

C(═

NOR³¹)N(R²⁹)R³⁰, —

Si(R¹³)(R¹⁴)R¹², phenyl, phenyl substituted with (Z)_p1, D-1 to D-60, E-1 to E-49 or M-1 to M-22,

R¹⁷ is C₁-C₆alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₆alkoxycarbonyl C₁-C₄alkyl, phenyl C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1 or C₁-C₆alkoxycarbonyl,

R¹⁸ is C₁-C₆alkyl, phenyl C₁-C₄alkyl or phenyl C₁-C₄alkyl substituted with (Z)_p1, or R¹⁸ together with R¹⁷ may form 5- or 6-membered ring with the nitrogen atom bonding them by forming C₄-C₅alkylene chain, in this case, the alkylene chain may contain one oxygen atom or sulfur atom, and may be arbitrarily substituted with methyl or methoxy,

R¹⁹ is C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R¹⁶, C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, C₃-C₆alkenyl, C₃-C₆haloalkenyl, C₃-C₆alkynyl, —

CHO, —

C(O)R²⁸, —

C(O)OR²⁸, —

C(O)NHR²⁹, —

C(O)N(R²⁹)R²⁸, —

C(S)NHR²⁹, —

C(S)N(R²⁹)R²⁸, —

S(O)₂R²⁸, —

S(O)₂NHR²⁹, —

S(O)₂N(R²⁹)R²⁸, phenyl, phenyl substituted with (Z)_p1, D-1 to D-13, D-15 to D-25, D-30 to D-37, D-39, D-40, D-42, D-45 to D-60, E-5, E-7, E-9, E-24, E-25, E-27, E-28, E-30 or E-31,

R^19a is C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆cycloalkyl, phenyl, phenyl substituted with (Z)_p1, D-1 to D-4, D-8 to D-10, D-15 to D-23, D-47 to D-55, E-4 to E-7, E-23 to E-27 or E-28,

R^19b is hydrogen atom or C₁-C₆alkyl, or R^19a together with R^19b may form 5- or 6-membered ring with the carbon atom bonding them by forming C₄ or C₅alkylene chain, in this case, the alkylene chain may contain one oxygen atom or sulfur atom,

R²⁰ is hydrogen atom, C₁-C₆alkyl, C₁-C₆haloalkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, cyano C₁-C₆alkyl, C₁-C₄alkoxycarbonyl C₁-C₄alkyl, C₂-C₆alkenyl, C₃-C₆alkynyl, —

CHO, —

C(O)R⁹, —

C(O)OR⁹, —

C(O)SR⁹, —

C(S)OR⁹, —

C(S)SR⁹ or C₁-C₆alkylsulfonyl,

R²² is halogen atom, cyano, C₁-C₆alkyl, C₁-C₆haloalkyl, C₁-C₆alkoxy, C₁-C₆alkoxycarbonyl, —

C(O)NH₂ or —

C(S)NH₂, when q1, q2, q3 or q4 is an integer of 2 or more, each R²² may be identical with or different from each other, further in case where two R²²s are present on the same carbon atom, the two R²²s together may form oxo, thioxo, imino, C₁-C₆alkylimino, C₁-C₆alkoxyimino or C₁-C₆alkylidene,

R²³ is hydrogen atom, C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R³², C₃-C₆cycloalkyl, C₃-C₆alkenyl, C₃-C₆alkynyl, —

OH, benzyloxy, —

CHO, —

C(O)R³³, —

C(O)OR³³, —

C(O)SR³³, —

C(O)NHR³⁴, —

C(O)N(R³⁴)R³³, —

S(O)₂R³³, phenyl, phenyl substituted with (Z)_p1 or D-5,

R²⁵ is hydrogen atom, C₁-C₆alkyl, C₁-C₆haloalkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, cyano C₁-C₆alkyl, phenyl C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1, C₃-C₆alkenyl, C₃-C₆alkynyl, —

CHO, —

C(O)R³³, —

C(O)OR³³, —

C(O)SR³³, C(O)NHR³⁴, —

C(O)N(R³⁴)R³³, —

C(S)R³³, —

C(S)OR³³, —

C(S)SR³³, —

C(S)NHR³⁴, —

C(S)N(R³⁴)R³³, —

S(O)₂R³³, —

S(O)₂N(R³⁴)R³³, di(C₁-C₆alkyl)phosphoryl, di(C₁-C₆alkyl)thiophosphoryl, tri(C₁-C₄alkyl)silyl, phenyl or phenyl substituted with (Z)_p1,

R²⁶ is hydrogen atom, C₁-C₆alkyl, C₃-C₆alkenyl, C₃-C₆alkynyl or C₁-C₆alkoxy, or R²⁶ together with R²⁵ may form 4- to 6-membered ring with the nitrogen atom bonding them by forming C₃-C₅alkylene chain, in this case, the alkylene chain may contain one oxygen atom, sulfur atom or nitrogen atom, and may substituted with C₁-C₆alkyl, oxo or thioxo,

R²⁷ is C₁-C₆alkyl, C₁-C₆haloalkyl, hydroxy C₁-C₆alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, C₁-C₄alkylcarbonyl C₁-C₄alkyl, C₁-C₄alkoxycarbonyl C₁-C₄alkyl, di(C₁-C₄alkyl)aminocarbonyl C₁-C₄alkyl, tri(C₁-C₄alkyl)silyl C₁-C₄alkyl, phenyl C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1, C₃-C₆alkenyl, C₃-C₆alkynyl, C₁-C₆alkylcarbonyl, C₁-C₆alkylthio, phenylthio, phenylthio substituted with (Z)_p1, —

C(O)NHR³⁴, —

C(O)N(R³⁴)R³³, —

C(S)NHR³⁴, —

C(S)N(R³⁴)R³³, phenyl, phenyl substituted with (Z)_p1, D-21, D-35, D-47 or D-50,

R²⁸ is C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R³², C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, C₃-C₆alkenyl, C₃-C₆haloalkenyl, C₃-C₆alkynyl, C₃-C₆haloalkynyl, phenyl, phenyl substituted with (Z)_p1, D-1 to D-60 or E-1 to E-49,

R²⁹ is hydrogen atom, C₁-C₆alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, cyano C₁-C₆alkyl, C₃-C₆alkenyl or C₃-C₆alkynyl, or R²⁹ together with R²⁸ may form 3- to 6-membered ring with the nitrogen atom bonding them by forming C₂-C₅alkylene chain, in this case, the alkylene chain may contain one oxygen atom or sulfur atom,

R³⁰ is C₁-C₆alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, tri(C₁-C₆alkyl)silyl C₁-C₄alkyl, phenyl C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1, C₃-C₈alkenyl, C₃-C₈haloalkenyl, C₃-C₈alkynyl or C₃-C₈haloalkynyl,

R³¹ is hydrogen atom, C₁-C₆alkyl, C₁-C₆haloalkyl or C₃-C₆cycloalkyl, or R³¹ together with R³⁰ may form 5- or 6-membered ring with the atom bonding them by forming C₂-C₃alkylene chain, in this case, the alkylene chain may be arbitrarily substituted with C₁-C₆alkyl,

R³² is halogen atom, cyano, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, —

OR³³, —

OC(O)R³³, OC(O)NHR³³, —

OC(O)N(R³⁴)R³³, S(O)_rR³³, —

SC(O)R³³, —

SC(O)NHR³³, —

SC(O)N(R³⁴)R³³, —

N(R³⁴)CHO, —

N(R³⁴)C(O)R³³, —

N(R³⁴)C(O)OR³³, —

C(O)OR³³, —

C(O)NHR³⁴, —

C(O)N(R³⁴)R³³, phenyl, phenyl substituted with (Z)_p1, D-1 to D-60 or E-1 to E-49,

R³³ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄haloalkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, C₁-C₄haloalkylthio C₁-C₄alkyl, C₁-C₄alkylsulfonyl C₁-C₄alkyl, C₁-C₄haloalkylsulfonyl C₁-C₄alkyl, cyano C₁-C₆alkyl, phenyl C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1, C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, C₃-C₆alkenyl, C₃-C₆haloalkenyl, C₃-C₆alkynyl, phenyl, phenyl substituted with (Z)_p1, D-1 to D-4, D-8 to D-13, D-15 to D-18, D-21, D-29 to D-37, D-47 to D-55, E-5, E-7, E-9, E-24, E-25, E-27, E-28, E-30, E-31 or E-34,

R³⁴ is hydrogen atom, C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆alkenyl or C₃-C₆alkynyl, or R³⁴ together with R³³ may form 3- to 6-membered ring with the nitrogen atom bonding them by forming C₂-C₅alkylene chain, in this case, the alkylene chain may contain one oxygen atom or sulfur atom.

3. The isoxazoline-substituted benzamide compound or the salt thereof according to claim 2, wherein

G is G-1, G-3, G-4, G-13, G-14, G-17, G-18, G-20, G-21 or G-22,

X is halogen atom, cyano, nitro, —

SF₅, C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R⁴, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, C₂-C₆alkenyl, C₂-C₆haloalkenyl, C₂-C₆alkynyl, C₂-C₆haloalkynyl, —

OR⁵, —

OSO₂R⁵, —

S(O)_rR⁵, —

C(O)OR⁹, —

C(O)SR⁹, —

C(S)OR⁹, —

C(S)SR⁹, —

C(S)NHR¹⁰, —

C(S)N(R¹⁰)R⁹, —

CH═

NOR¹¹, —

C(R⁹)═

NOR¹¹, —

Si(R¹³)(R¹⁴)R¹², E-10, E-12, E-18, E-32, E-35 or E-43, when m is 2 or 3, each X may be identical with or different from each other,

further, when two Xs are adjacent, the adjacent two Xs may form 5-membered or 6-membered ring together with carbon atoms to which the two Xs are bonded by forming —

CF₂OCF₂—

, —

OCF₂O—

, —

CF₂OCF₂O—

or —

OCF₂CF₂O—

,

Y is halogen atom, cyano, nitro, C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R⁴, —

OR⁵, —

OSO₂R⁵, —

S(O)_rR⁵, —

NR⁷, —

N(R⁷)R⁶, —

N═

C(R⁹)OR⁸, —

C(O)NH₂ or —

C(S)NH₂, when n is 2 or 3, each Y may be identical with or different from each other,

R¹ is C₁-C₈alkyl, C₁-C₈alkyl arbitrarily substituted with R¹⁶, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, C₃-C₈alkenyl, C₃-C₈haloalkenyl, C₃-C₈alkynyl, C₃-C₈haloalkynyl, —

N(R²⁰)R⁹, —

C(O)N(R¹⁰)R⁹, —

C(S)N(R¹⁰)R⁹, phenyl substituted with (Z)_p1, D-8 to D-18, D-21 to D-24, D-26 to D-40, D-42, D-45 to D-58, E-4, E-5, E-7, E-8, E-9, E-23 to E-25, E-27, E-28, E-30, E-31 or E-34,

R² is hydrogen atom, C₁-C₆alkyl, C₁-C₆haloalkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, cyano C₁-C₆alkyl, C₃-C₆cycloalkyl, C₃-C₆alkenyl, C₃-C₆alkynyl, —

OH, C₁-C₆alkoxy, C₁-C₆alkylcarbonyloxy, C₁-C₆alkoxycarbonyloxy, C₁-C₆alkylsulfonyloxy, C₁-C₆haloalkylthio, phenylthio, phenylthio substituted with (Z)_p1, C₁-C₆alkylsulfonyl, —

SN(R¹⁸)R¹⁷, —

NHR²⁰, —

N═

CHR^19b, —

N═

C(R^19b)^19a, —

C(O)R⁹, —

C(O)OR⁹, —

C(O)SR⁹, —

C(S)OR⁹ or —

C(S)SR⁹, or R² together with R¹ may form 3- to 7-membered ring with the nitrogen atom bonding them by forming C₂-C₆alkylene chain, in this case, the alkylene chain may contain one oxygen atom or sulfur atom,

R³ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, C₃-C₆halocycloalkyl C₁-C₄alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄haloalkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, C₁-C₄alkylsulfinyl C₁-C₄alkyl, C₁-C₄alkylsulfonyl C₁-C₄alkyl, C₁-C₄haloalkylthio C₁-C₄alkyl, C₁-C₄haloalkylsulfinyl C₁-C₄alkyl, C₁-C₄haloalkylsulfonyl C₁-C₄alkyl, cyano C₁-C₆alkyl, C₁-C₄alkoxy C₁-C₄haloalkyl, C₁-C₄haloalkoxy C₁-C₄haloalkyl, C₁-C₄alkylthio C₁-C₄haloalkyl, C₁-C₄alkylsulfinyl C₁-C₄haloalkyl, C₁-C₄alkylsulfonyl C₁-C₄haloalkyl, C₁-C₄haloalkylthio C₁-C₄haloalkyl, C₁-C₄haloalkylsulfinyl C₁-C₄haloalkyl, C₁-C₄haloalkylsulfonyl C₁-C₄haloalkyl, cyano C₁-C₆haloalkyl, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, E-4 to E-7, E-23 to E-27 or E-28,

R⁴ is halogen atom, cyano, —

OH, C₁-C₆alkoxy, C₁-C₆haloalkoxy, C₁-C₆alkylthio, C₁-C₆haloalkylthio, C₁-C₆alkylsulfinyl, C₁-C₆haloalkylsulfinyl, C₁-C₆alkylsulfonyl, C₁-C₆haloalkylsulfonyl or tri(C₁-C₆alkyl)silyl,

R⁵ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₁-C₃haloalkoxy C₁-C₃haloalkyl, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, C₂-C₆alkenyl, C₂-C₆haloalkenyl, C₃-C₆alkynyl, C₃-C₆haloalkynyl, E-4 to E-9, E-23 to E-27 or E-28,

R⁶ is C₁-C₆alkyl, C₁-C₆haloalkyl, —

S(O)₂R⁹, —

CHO, —

C(O)R⁹, —

C(O)OR⁹, —

C(O)SR⁹, —

C(S)OR⁹ or —

C(S)SR⁹,

R⁷ is hydrogen atom, C₁-C₆alkyl or C₁-C₆haloalkyl,

R⁹ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, C₁-C₆alkoxy C₁-C₄alkyl, C₁-C₆alkylthio C₁-C₄alkyl, cyano C₁-C₆alkyl, phenyl C₁-C₄alkyl, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, C₃-C₆alkenyl or C₃-C₆alkynyl,

R¹⁰ is hydrogen atom or C₁-C₆alkyl, or R¹⁰ together with R⁹ may form 5- or 6-membered ring with the nitrogen atom bonding them by forming C₄ or C₅alkylene chain, in this case, the alkylene chain may contain one oxygen atom or sulfur atom,

R¹¹ is C₁-C₆alkyl or C₁-C₆haloalkyl, or R¹¹ together with R⁹ may form 5- or 6-membered ring with the atom bonding them by forming C₂ or C₃alkylene chain, in this case, the alkylene chain may be arbitrarily substituted with C₁-C₆alkyl,

R¹⁵ is C₁-C₆alkyl or C₁-C₆haloalkyl,

R¹⁶ is halogen atom, cyano, C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, —

OR²⁵, —

N(R²⁶)R²⁵, S(O)_rR²⁷, —

SO₂NHR²⁹, —

SO₂N(R⁹)R²⁸, —

CHO, —

C(O)R²⁸, —

C(O)OR²⁸, —

C(O)NHR²⁹, —

C(O)N(R²⁹)R²⁸—

C(O)N(R²⁹)OR²⁸, —

C(S)NHR²⁹, —

C(S)N(R²⁹)R²¹, —

C(R³¹)═

NOH, —

C(R³¹)═

NOR³⁰, —

C(═

NR³¹)OR³⁰, —

C(═

NR³¹)SR³⁰, —

C(═

NR³¹)N(R²⁹)R³⁰, —

C(═

NOR³¹)NHR²⁹, —

C(═

NOR³¹)N(R²⁹)R³⁰, phenyl, phenyl substituted with (Z)_p1, D-1 to D-4, D-8 to D-42, D-47 to D-55, E-4 to E-12, E-14, E-16 to E-19, E-21 to E-23, E-26 to E-35, E-40 to E-45, E-48, M-2, M-3, M-5, M-8 to M-10, M-14, M-15 or M-16,

R¹⁷ is C₁-C₆alkyl, C₁-C₆alkoxycarbonyl C₁-C₄alkyl or C₁-C₆alkoxycarbonyl,

R¹⁸ is C₁-C₆alkyl or benzyl,

R¹⁹ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆cyclaolakyl C₁-C₆alkyl, phenyl C₁-C₆alkyl, phenyl C₁-C₆alkyl substituted with (Z)_p1, C₃-C₆cycloalkyl, C₃-C₆alkenyl, C₃-C₆haloalkenyl, C₃-C₆alkynyl, —

C(O)R²⁸, —

C(O)OR²⁸, —

C(O)NHR²⁹, —

C(O)N(R²⁹)R²⁸, —

C(S)NHR²⁹, —

C(S)N(R⁹)R²⁸, C₁-C₆alkylsulfonyl, C₁-C₆haloalkylsulfonyl, phenylsulfonyl, phenylsulfonyl substituted with (Z)_p1, phenyl, phenyl substituted with (Z)_p1, D-1 to D-4, D-18, D-21, D-25, D-30 to D-35, D-47 to D-55 or D-56,

R^19a is C₁-C₆alkyl,

R^19b is hydrogen atom or C₁-C₆alkyl,

R²⁰ is hydrogen atom, C₁-C₆alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, cyano C₁-C₆alkyl, C₃-C₆alkenyl, C₃-C₆alkynyl, —

CHO, C₁-C₆alkylcarbonyl, C₁-C₆haloalkylcarbonyl, C₁-C₆alkoxycarbonyl, C₁-C₆haloalkoxycarbonyl or C₁-C₆alkylsulfonyl,

R²² is C₁-C₄alkyl or C₁-C₄haloalkyl, or two R²²s present on the same carbon atom may together form oxo, or thioxo,

R²³ is hydrogen atom, C₁-C₆alkyl, —

CHO, C₁-C₆alkylcarbonyl, C₁-C₆haloalkylcarbonyl, C₁-C₆alkoxycarbonyl, C₁-C₆alkylsulfonyl or C₁-C₆haloalkylsulfonyl,

R²⁵ is hydrogen atom, C₁-C₆alkyl, C₁-C₆haloalkyl, —

C(O)R³³, —

C(O)OR³³, —

C(O)SR³³, —

C(O)NHR³⁴, —

C(O)N(R³⁴)R³³, —

C(S)R³³, —

C(S)OR³³, —

C(S)SR³³, —

C(S)NHR³⁴, —

C(S)N(R³⁴)R³³, —

S(O)₂R³³, —

S(O)₂N(R³⁴)R³³, di(C₁-C₆alkyl)thiophosphoryl, phenyl or phenyl substituted with (Z)_p1,

R²⁶ is hydrogen atom or C₁-C₆alkyl, or R²⁶ together with R²⁵ may form 4- to 6-membered ring with the nitrogen atom bonding them by forming C₃-C₅alkylene chain, in this case, the alkylene chain may contain one oxygen atom, sulfur atom or nitrogen atom, and may be substituted with C₁-C₆alkyl, oxo or thioxo,

R²⁷ is C₁-C₆alkyl, C₁-C₆haloalkyl, tri(C₁-C₄alkyl)silyl C₁-C₄alkyl, C₁-C₆alkylthio, —

C(O)NHR³⁴, —

C(O)N(R³⁴)R³³, —

C(S)NHR³⁴, —

C(S)N(R³⁴)R³³, phenyl, phenyl substituted with (Z)_p1, D-47 or D-50,

R²⁸ is C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R³², C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, C₃-C₆alkenyl, C₃-C₆haloalkenyl, C₃-C₆alkynyl, C₃-C₆haloalkynyl, phenyl or phenyl substituted with (Z)_p1,

R²⁹ is hydrogen atom, C₁-C₆alkyl, C₃-C₆alkenyl or C₃-C₆alkynyl, or R²⁹ together with R²⁸ may form 3- to 6-membered ring with the nitrogen atom bonding them by forming C₂-C₅alkylene chain, in this case, the alkylene chain may contain one oxygen atom or sulfur atom,

R³⁰ is C₁-C₆alkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, phenyl C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1, C₃-C₈alkenyl or C₃-C₈alkynyl,

R³¹ is hydrogen atom or C₁-C₆alkyl, or R³¹ together with R³⁰ may form 5- or 6-membered ring with the atom bonding them by forming C₂ or C₃alkylene chain, in this case, the alkylene chain may be arbitrarily substituted with C₁-C₆alkyl,

R³² is halogen atom, cyano, C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, C₁-C₄alkoxy, C₁-C₄haloalkoxy, C₁-C₄alkylthio, C₁-C₄haloalkylthio, C₁-C₄alkoxycarbonyl, —

C(O)NH₂, C₁-C₄alkylaminocarbonyl, di(C₁-C₄alkyl)aminocarbonyl, phenyl or phenyl substituted with (Z)_p1,

R³³ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, C₁-C₄alkylsulfonyl C₁-C₄alkyl, phenyl C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1, C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, C₃-C₆alkenyl, C₃-C₆alkynyl, phenyl or phenyl substituted with (Z)_p1,

R³⁴ is hydrogen atom or C₁-C₆alkyl,

m is an integer of 1 to 3,

n is an integer of 0 to 2,

q1 is 0,

q2 is an integer of 0 to 3,

q3 is an integer of 0 to 2, and

q4 is an integer of 0 to 2.

4. The isoxazoline-substituted benzamide compound or the salt thereof according to claim 3, wherein

A¹ is carbon atom or nitrogen atom,

A² and A³ are carbon atom,

G is G-1,

X is halogen atom, cyano, nitro, —

SF₅, C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R⁴, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, C₂-C₆alkenyl, C₂-C₆haloalkenyl, C₂-C₆alkynyl, C₂-C₆haloalkynyl, —

OR⁵, —

OSO₂R⁵, —

S(O)_rR⁵ or tri(C₁-C₆alkyl)silyl, when m is 2 or 3, each X may be identical with or different from each other,

further, when two Xs are adjacent, the adjacent two Xs may form 5-membered or 6-membered ring together with carbon atoms to which the two Xs are bonded by forming —

CF₂OCF₂—

, —

OCF₂O—

, —

CF₂OCF₂O—

or —

OCF₂CF₂O—

,

Y is halogen atom, cyano, nitro, C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R⁴, —

OR⁵, —

OSO₂R⁵, —

S(O)_rR⁵, —

NHR⁷, —

N(R⁷)R⁶, —

C(O)NH₂ or —

C(S)NH₂, when n is 2 or 3, each Y may be identical with or different from each other,

R¹ is C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R¹⁶, C₃-C₈cycloalkyl, C₃-C₆halocycloalkyl, C₃-C₆alkenyl, C₃-C₆haloalkenyl, C₃-C₆alkynyl, C₃-C₆haloalkynyl, —

N(R²⁰)R¹⁹, —

C(O)N(R¹⁰)R⁹, —

C(S)N(R¹⁰)R⁹, phenyl substituted with (Z)_p1, D-8, D-10, D-11, D-13 to D-15, D-17, D-18, D-21 to D-23, D-26 to D-37, D-39, D-40, D-42, D-45, D-47 to D-54, D-56, D-58, E-4, E-5, E-7 or E-9,

R² is hydrogen atom, C₁-C₆alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, cyano C₁-C₆alkyl, C₃-C₆cycloalkyl, C₃-C₆alkenyl, C₃-C₆alkynyl, —

OH, C₁-C₆alkylcarbonyloxy, C₁-C₆alkylsulfonyloxy, —

NH₂, —

C(O)R⁹, —

C(O)OR⁹, —

C(O)SR⁹, —

C(S)OR⁹ or —

C(S)SR⁹,

R³ is C₁-C₆haloalkyl, C₁-C₄alkoxy C₁-C₄haloalkyl, C₁-C₄haloalkoxy C₁-C₄haloalkyl, C₁-C₄alkylthio C₁-C₄haloalkyl, C₁-C₄haloalkylthio C₁-C₄haloalkyl, cyano C₁-C₆haloalkyl or C₃-C₈halocycloalkyl,

R⁴ is halogen atom, cyano, —

OH, C₁-C₆alkoxy, C₁-C₆haloalkoxy, C₁-C₆alkylthio, C₁-C₆haloalkylthio, C₁-C₆alkylsulfinyl, C₁-C₆haloalkylsulfinyl, C₁-C₆alkylsulfonyl, C₁-C₆haloalkylsulfonyl or tri(C₁-C₆alkyl)silyl,

R⁵ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₁-C₃haloalkoxy C₁-C₃haloalkyl, C₃-C₈cycloalkyl, C₃-C₈halocycloalkyl, C₂-C₆alkenyl, C₂-C₆haloalkenyl, C₃-C₆alkynyl or C₃-C₆haloalkynyl,

R⁶ is C₁-C₆alkyl, C₁-C₆haloalkyl, —

CHO, C₁-C₆alkylcarbonyl, C₁-C₆haloalkylcarbonyl, C₃-C₆cycloalkylcarbonyl, C₃-C₆halocycloalkylcarbonyl, C₁-C₆alkoxycarbonyl, C₁-C₆haloalkoxycarbonyl, C₁-C₆alkylthiocarbonyl, C₁-C₆alkoxythiocarbonyl, C₁-C₆alkyldithiocarbonyl, C₁-C₆alkylsulfonyl or C₁-C₆haloalkylsulfonyl,

R⁷ is hydrogen atom or C₁-C₆alkyl,

R⁹ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, C₁-C₆alkoxy C₁-C₄alkyl, C₁-C₆alkylthio C₁-C₄alkyl, cyano C₁-C₆alkyl, C₃-C₈cycloalkyl, C₃-C₆alkenyl or C₃-C₆alkynyl,

R¹⁶ is halogen atom, cyano, C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, —

OR²⁵, —

N(R²⁶)R²⁵, —

S(O)_rR²⁷, —

SO₂NHR²⁹, —

SO₂N(R²⁹)R²⁸, —

C(O)R²⁸, —

C(O)OR²⁸, —

C(O)NHR²⁹, —

C(O)N(R²⁹)R²⁸, —

C(O)N(R²⁹)OR²⁸, —

C(S)NHR²⁹, —

C(S)N(R²⁹)R²⁸, —

C(R³¹)═

NOH, —

C(R³¹)═

NOR³⁰, —

C(═

NR³¹)OR³⁰, —

C(═

NR³¹)SR³⁰, phenyl, phenyl substituted with (Z)_p1, D-1 to D-4, D-8 to D-38, D-47 to D-55, E-4 to E-12, E-18, E-19, E-32, E-35, E-43, M-2, M-3, M-5, M-8, M-9 or M-10,

R¹⁹ is C₁-C₆haloalkyl, C₃-C₆cycloalkyl, —

C(O)R²⁸, —

C(O)OR²⁸, —

C(O)NHR²⁹, —

C(O)N(R²⁹)R²⁸, —

C(S)NHR²⁹, —

C(S)N(R²⁹)R²⁸, phenyl, phenyl substituted with (Z)_p1, D-3, D-4, D-21, D-47, D-50, D-51, D-53 or D-54,

R²⁰ is hydrogen atom, C₁-C₆alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, cyano C₁-C₆alkyl, C₃-C₆alkenyl, C₃-C₆alkynyl, —

CHO, C₁-C₆alkylcarbonyl, C₁-C₆alkoxycarbonyl or C₁-C₆alkylsulfonyl,

R²⁵ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₁-C₆alkylcarbonyl, C₁-C₆alkoxycarbonyl, C₁-C₆alkylaminocarbonyl, di(C₁-C₆alkyl)aminocarbonyl or C₁-C₆alkylsulfonyl,

R²⁶ is hydrogen atom or C₁-C₆alkyl,

R²⁷ is C₁-C₆alkyl, C₁-C₆haloalkyl or tri(C₁-C₄alkyl)silyl C₁-C₄alkyl,

R²⁸ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, C₁-C₄alkoxy C₁-C₄alkyl, C₁-C₄alkylthio C₁-C₄alkyl, cyano C₁-C₆alkyl, phenyl C₁-C₄alkyl, phenyl C₁-C₄alkyl substituted with (Z)_p1, C₃-C₆cycloalkyl, C₃-C₆alkenyl, C₃-C₆haloalkenyl, C₃-C₆alkynyl, phenyl or phenyl substituted with (Z)_p1,

R²⁹ is hydrogen atom, C₁-C₆alkyl, C₃-C₆alkenyl or C₃-C₆alkynyl,

R³⁰ is C₁-C₆alkyl or C₃-C₆cycloalkyl C₁-C₄alkyl,

R³¹ is hydrogen atom or C₁-C₆alkyl, or R³¹ together with R³⁰ may form 5- or 6-membered ring with the atom bonding them by forming C₂ or C₃alkylene chain.

5. The isoxazoline-substituted benzamide compound or the salt thereof according to claim 4, wherein

X is halogen atom, cyano, nitro, —

SF₅, C₁-C₆alkyl, C₁-C₆haloalkyl, hydroxy C₁-C₆haloalkyl, C₁-C₆alkoxy C₁-C₆haloalkyl, C₁-C₆haloalkoxy C₁-C₆haloalkyl, C₃-C₈halocycloalkyl, —

OR⁵, —

OSO₂R⁵ or —

S(O)_rR⁵, when m is 2 or 3, each X may be identical with or different from each other,

Y is halogen atom, cyano, nitro, C₁-C₄alkyl, C₁-C₄haloalkyl, C₁-C₄alkoxy, C₁-C₄haloalkoxy, C₁-C₆alkylthio, C₁-C₆haloalkylthio, C₁-C₆alkylsulfonyl, C₁-C₆haloalkylsulfonyl, —

NHR⁷ or —

N(R⁷)R⁶,

R¹ is C₁-C₆alkyl, C₁-C₆alkyl arbitrarily substituted with R¹⁶, C₃-C₆cycloalkyl, C₃-C₆alkenyl, C₃-C₆haloalkenyl, C₃-C₆alkynyl, —

N(R²⁰)R¹⁹, D-8, D-10, D-13 to D-15, D-18, D-21, D-34, D-35, D-47, D-48, D-50 to D-53 or D-54,

R² is hydrogen atom, C₁-C₆alkyl, C₁-C₄alkoxy C₁-C₄alkyl, cyano C₁-C₆alkyl, C₃-C₆alkynyl, —

C(O)R⁹ or —

C(O)OR⁹,

R³ is C₁-C₆haloalkyl or C₃-C₈halocycloalkyl,

R⁵ is C₁-C₆alkyl, C₁-C₆haloalkyl or C₁-C₃haloalkoxy C₁-C₃haloalkyl,

R⁶ is C₁-C₆alkyl, —

CHO, C₁-C₆alkylcarbonyl, C₁-C₆haloalkylcarbonyl, C₁-C₆alkoxycarbonyl, C₁-C₆alkylthiocarbonyl, C₁-C₆alkoxythiocarbonyl, C₁-C₆alkyldithiocarbonyl, C₁-C₆alkylsulfonyl or C₁-C₆haloalkylsulfonyl,

R⁹ is C₁-C₆alkyl, C₁-C₆alkoxy C₁-C₄alkyl, C₁-C₆alkylthio C₁-C₄alkyl, C₃-C₈cycloalkyl, C₃-C₆alkenyl or C₃-C₆alkynyl,

R¹⁶ is halogen atom, cyano, C₃-C₆cycloalkyl, C₃-C₆halocycloalkyl, C₁-C₆alkoxy, C₁-C₆haloalkoxy, C₁-C₆alkylthio, C₁-C₆haloalkylthio, C₁-C₆alkylsulfinyl, C₁-C₆haloalkylsulfinyl, C₁-C₆alkylsulfonyl, C₁-C₆haloalkylsulfonyl, C₁-C₆alkylcarbonyl, —

C(O)R²⁸, —

C(O)NHR¹⁹, —

C(O)N(R²⁹)R²⁸, —

C(S)NH₂, —

C(R³¹)═

NOH, —

C(R³¹)═

NOR³⁰, phenyl, phenyl substituted with (Z)_p1, D-1 to D-4, D-8 to D-38, D-47 to D-55, E-4 to E-7, E-10, E-11 or E-32,

R¹⁹ is C₁-C₆haloalkyl, —

C(O)R²¹—

C(O)OR²⁸, phenyl, phenyl substituted with (Z)_p1, D-3, D-4, D-21, D-47, D-50, D-51, D-53 or D-54,

R²⁰ is hydrogen atom or C₁-C₆alkyl,

R²⁸ is C₁-C₆alkyl, C₁-C₆haloalkyl, C₃-C₆cycloalkyl C₁-C₄alkyl, C₃-C₆cycloalkyl, C₃-C₆alkenyl or C₃-C₆alkynyl,

R²⁹ is hydrogen atom or C₁-C₆alkyl,

R³⁰ is C₁-C₆alkyl,

R³¹ is hydrogen atom or C₁-C₆alkyl, and

n is an integer of 0 or 1.

9. A pesticide containing as an active ingredient one or more selected from isoxazoline-substituted benzamide compound and the salt thereof according to claim 1.

10. An agrochemical containing as an active ingredient one or more selected from isoxazoline-substituted benzamide compound and the salt thereof according to claim 1.

11. An endo- or ecto-parasiticide for mammals or birds containing as an active ingredient one or more selected from isoxazoline-substituted benzamide compound and the salt thereof according to claim 1.

12. An insecticide or acaricide containing as an active ingredient one or more selected from isoxazoline-substituted benzamide compound and the salt thereof according to any one of claim 1.

6. 3,5-Bis (substituted aryl) substituted isoxazoline compound of formula (2) or a salt thereof:

7. 4-Hydroxyiminomethyl substituted benzamide compound of formula (3) or

8. Substituted alkenylbenzene compound of formula (4):

wherein

X¹ is halogen atom, —

SF₅, C₁-C₆haloalkyl, hydroxy C₁-C₆haloalkyl, C₁-C₆alkoxy C₁-C₆haloalkyl, C₃-C₈halocycloalkyl, C₁-C₆haloalkoxy, C₁-C₃haloalkoxy C₁-C₃haloalkoxy, C₁-C₆haloalkylthio, C₁-C₆haloalkylsulfinyl or C₁-C₆haloalkylsulfonyl,

X³ is hydrogen atom, halogen atom, cyano, nitro, C₁-C₆alkyl, C₁-C₆haloalkyl, C₁-C₆alkoxy or C₁-C₆alkylthio,

X⁴ is hydrogen atom, halogen atom, cyano, C₁-C₄alkyl, C₁-C₄alkoxy or C₁-C₄haloalkoxy,

R³ is —

C(R^3a)(R^3b)R^3c,

R^3a and R^3b independently of each other are halogen atom, or R^3a and R^3b together may form 3- to 6-membered ring together with the carbon atom bonding them by forming C₂-C₅haloalkylene chain,

R^3c is hydrogen atom, halogen atom, C₁-C₅alkyl, C₁-C₅haloalkyl, C₁-C₄haloalkoxy or C₁-C₄haloalkylthio, with a proviso that in case where X¹ is fluorine atom, chlorine atom or trifluoromethyl and both X² and X³ are hydrogen atom, in case where both X¹ and X² are fluorine atom and X³ is hydrogen atom, and in case where both X¹ and X² are trifluoromethyl and X³ is hydrogen atom, R^3c is hydrogen atom, chlorine atom, bromine atom, iodine atom, C₁-C₅alkyl, C₁-C₅haloalkyl, C₁-C₄haloalkoxy or C₁-C₄haloalkylthio.