Silicone hydrogel contact lens

• US 20070066706A1
• Filed: 09/20/2006
• Published: 03/22/2007
• Est. Priority Date: 08/27/2004
• Status: Active Grant

• Current Assignee: Coopervision International Limited (The Cooper Cos., Inc.)
• Original Assignee: CooperVision Incorporated (The Cooper Cos., Inc.)
• Inventors: Back, Arthur, Manesis, Nick
• Granted Patent: US 8,367,746 B2
• Time in Patent Office: Days
• US Class Current: 523/106
• CPC Class Codes: C08L 51/085 on to polysiloxanes
• CPC Class Codes: C08L 83/04 Polysiloxanes
• CPC Class Codes: G02B 1/043 Contact lenses

Abstract

Silicone hydrogel contact lenses are provided which have reduced modulus and contact angle properties, and which have acceptable wettabilities for use in daily wear and extended or continuous wear applications.

Claims

1. A contact lens comprising

a soft lens body having an anterior surface and a posterior surface at least one of which is not surface treated, the lens body comprising at least one hydrophilic silicon-containing polymeric material and having a contact angle hysteresis of less than 15°

and a modulus of less than 1 MPa.

2. The contact lens of claim 1 which is a silicone hydrogel contact lens.

3. The contact lens of claim 1 wherein the lens body has an advancing contact angle of about 70°

or less.

4. The contact lens of claim 1 wherein the lens body has an advancing contact angle of about 60°

or less.

5. The contact lens of claim 1 wherein the lens body has a contact angle hysteresis of less than 13°

.

6. The contact lens of claim 1, wherein the lens body has an oxygen permeability, a water content, a surface wettability, a modulus, and a design effective in facilitating ophthalmically compatible wearing of the contact lens by the lens wearer at least for one day.

7. The contact lens of claim 1, wherein the lens body has an oxygen permeability, a water content, a surface wettability, a modulus, and a design effective in facilitating ophthalmically compatible wearing of the contact lens by the lens wearer for about thirty days.

8. The contact lens of claim 1, wherein the lens body has an oxygen permeability of at least about 50 barrers.

9. The contact lens of claim 1, wherein the lens body has an oxygen permeability of at least about 120 barrers.

10. The contact lens of claim 1, wherein the lens body has a modulus less than about 0.8 MPa.

11. The contact lens of claim 1, wherein the lens body has a water content of at least about 30% by weight.

12. The contact lens of claim 1, wherein both the anterior and posterior surfaces are not surface treated.

13. The contact lens of claim 1, wherein the lens body has an ionoflux of no greater than about 5 10⁻

3 mm²/min.

14. A contact lens comprising:

a soft lens body having an anterior surface and a posterior surface at least one of which is not surface treated, the lens body comprising at least one hydrophilic silicon-containing polymeric material and having a receding contact angle of 49°

or less, a contact angle hysteresis of 45°

or less, and a modulus of less than 1 MPa.

15. The contact lens of claim 14 which is a silicone hydrogel contact lens.

16. The contact lens of claim 14 wherein the lens body has a contact lens hysteresis of about 30°

or less.

17. The contact lens of claim 14, wherein the lens body has an oxygen permeability, a water content, a surface wettability, a modulus, and a design effective in facilitating ophthalmically compatible wearing of the contact lens by the lens wearer at least for one day.

18. The contact lens of claim 14, wherein the lens body has an oxygen permeability, a water content, a surface wettability, a modulus, and a design effective in facilitating ophthalmically compatible wearing of the contact lens by the lens wearer for about thirty days.

19. The contact lens of claim 14, wherein the lens body has an oxygen permeability of at least about 50 barrers.

20. The contact lens of claim 14, wherein the lens body has an oxygen permeability of at least about 120 barrers.

21. The contact lens of claim 14, wherein the lens body has a modulus less than about 0.8 MPa.

22. The contact lens of claim 14, wherein the lens body has a water content of at least about 30% by weight.

23. The contact lens of claim 14, wherein both the anterior and posterior surfaces are not surface treated.

24. A contact lens comprising:

a soft lens body having an anterior surface and a posterior surface, the lens body comprising at least one hydrophilic silicon-containing polymeric material and having a modulus less than 1 MPa an advancing contact angle and a receding contact angle, the sum of the advancing contact angle and the receding contact angle being in a range of more than 94°

to less than 117°

, and a contact angle hysteresis of less than 30°

.

25. The contact lens of claim 24 which is a silicone hydrogel lens.

26. The contact lens of claim 24 wherein the sum of the advancing contact angle and the receding contact angle is in a range of 95°

to 115°

.

27. The contact lens of claim 24 wherein the sum of the advancing contact angle and the receding contact angle is about 110°

or less.

28. The contact lens of claim 24 wherein the contact angle hysteresis is less than 20°

.

29. The contact lens of claim 24 wherein the advancing contact angle is less than about 90°

.

30. The contact lens of claim 24 wherein the advancing contact angle is less than about 65°

.

31. The contact lens of claim 24, wherein the anterior surface and the posterior surfaces are not surface treated.

32. The contact lens of claim 24, wherein the lens body has an oxygen permeability, a water content, a surface wettability, a modulus, and a design effective in facilitating ophthalmically compatible wearing of the contact lens by the lens wearer at least for one day.

33. The contact lens of claim 24, wherein the lens body has an oxygen permeability, a water content, a surface wettability, a modulus, and a design effective in facilitating ophthalmically compatible wearing of the contact lens by the lens wearer for about thirty days.

34. The contact lens of claim 24, wherein the lens body has an oxygen permeability of at least about 50 barrers.

35. The contact lens of claim 24, wherein the lens body has an oxygen permeability of at least about 120 barrers.

36. The contact lens of claim 24, wherein the lens body has a modulus less than about 0.8 MPa.

37. The contact lens of claim 24, wherein the lens body has a water content of at least about 30% by weight.

38. The contact lens of claim 24, wherein the lens body has an anterior surface and a posterior surface, and at least one of the anterior and posterior surfaces is not surface treated.