Method for enhancing effects of colorants and conditioners

• US 20070067924A1
• Filed: 08/30/2006
• Published: 03/29/2007
• Est. Priority Date: 09/28/2005
• Status: Active Grant

• Current Assignee: E. I. du Pont de Nemours and Company (Corteva, Inc.)
• Original Assignee: E. I. du Pont de Nemours and Company (Corteva, Inc.)
• Inventors: Wang, Hong, O'Brien, John, Beck, William
• Granted Patent: US 7,736,633 B2
• Time in Patent Office: Days
• US Class Current: 8/405
• CPC Class Codes: A61K 2800/94 Involves covalent bonding to the substrate
• CPC Class Codes: A61K 8/64 Proteins; Peptides; Derivatives or degradation products thereof
• CPC Class Codes: A61Q 17/005 Antimicrobial preparations
• CPC Class Codes: A61Q 17/04 Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: A61Q 19/04 for chemically tanning the skin topical sun or radiation screening or tanning preparations A61Q17/04
• CPC Class Codes: A61Q 3/00 Manicure or pedicure preparations
• CPC Class Codes: A61Q 5/10 Preparations for permanently dyeing the hair
• CPC Class Codes: C07K 2319/00 Fusion polypeptide

Abstract

Methods are provided for enhancing the longevity of the binding of various benefit agents to hair and skin. Applications of traditional and non-traditional colorants and conditioners to hair and skin are amended with compositions of hair or skin-binding peptides respectively. The presence of the hair or skin-binding peptide compositions act to increase the longevity of the applied colorant or conditioner on the hair or skin.

Claims

1. A method for applying a benefit agent to hair comprising the steps of:

a) providing a hair benefit agent having affinity to hair;

b) providing a composition comprising a hair-binding peptide;

c) applying the benefit agent and the composition comprising a hair-binding peptide to hair for a time sufficient for the hair benefit agent and the hair-binding peptide to bind to hair.

2. A method according to claim 1 wherein the hair benefit agent is selected from the group consisting of hair colorants and hair conditioners.

3. A method according to claim 2 wherein the hair colorant is selected from the group consisting of dyes, pigments and nanoparticles.

4. A method according to claim 3 wherein the dye is selected from the group consisting of 4-hydroxypropylamino-3-nitrophenol, 4-amino-3-nitrophenol, 2-amino-6-chloro-4-nitrophenol, 2-nitro-paraphenylenediamine, N,N-hydroxyethyl-2-nitro-phenylenediamine, 4-nitro-indole, 2-nitro-5-glyceryl methylaniline, 3-metylamino-4-nitrophenoxyethanol, 3-nitro-p-hydroxyethylaminophenol, hydroxyanthraquinoneaminopropylmethyl morpholinium methosulfate, Henna, HC Blue 1, HC Blue 2, HC Yellow 4, HC Red 3, HC Red 5, HC Red 7, HC Violet 1, HC Violet 2, HC Blue 7, HC Blue 10, HC Blue 12, HC Yellow 2, HC Yellow 6, HC Yellow 8, HC Yellow 12, HC Orange 2, HC Orange 3, HC Brown 2, D&

C Yellow 1, D&

C Yellow 3, D&

C Blue 1, Disperse Blue 3, Disperse Violet 1, Disperse Orange, Disperse Violet 4, Disperse Black 9, Basic Orange 31, Basic Yellow 57, Basic Yellow 87, HC Yellow No. 9, Basic Blue 26, Basic Blue 7, Basic Blue 99, Basic Violet 14, Basic Violet 2, Basic Brown 16, Basic Brown 17, Basic Red 2, Basic Red 51, Acid Red 33, Brilliant Black 1, eosin derivatives, and halogenated fluorescein derivatives.

5. A method according to claim 3 wherein the wherein the pigment is selected from the group consisting of D&

C Red No. 36, D&

C Red No. 30, D&

C Orange No. 17, Green 3 Lake, Ext. Yellow 7 Lake, Orange 4 Lake, Red 28 Lake, the calcium lakes of D&

C Red Nos. 7, 11, 31 and 34, the barium lake of D&

C Red No. 12, the strontium lake D&

C Red No. 13, the aluminum lakes of FD&

C Yellow No. 5 and No. 6, the aluminum lakes of FD&

C No. 40, the aluminum lakes of D&

C Red Nos. 21, 22, 27, and 28, the aluminum lakes of FD&

C Blue No. 1, the aluminum lakes of D&

C Orange No. 5, the aluminum lakes of D&

C Yellow No. 10;

the zirconium lake of D&

C Red No. 33, Cromophthal®

Yellow, Sunfast®

Magenta, Sunfast®

Blue, iron oxides, calcium carbonate, aluminum hydroxide, calcium sulfate, kaolin, ferric ammonium ferrocyanide, magnesium carbonate, carmine, barium sulfate, mica, bismuth oxychloride, zinc stearate, manganese violet, chromium oxide, titanium dioxide, titanium dioxide nanoparticles, zinc oxide, barium oxide, ultramarine blue, bismuth citrate, hydroxyapatite, zirconium silicate, and carbon black particles.

6. A method according to claim 3 wherein the nanoparticles are colored polymer nanoparticles comprised of materials selected from the group consisting of polystyrene, polymethylmethacrylate, polyvinyltoluene, styrene/butadiene copolymer, and latex.

7. A method according to claim 2 wherein the hair conditioner is selected from the group consisting of cationic polymers, cationic surfactants, fatty alcohols, fatty amines, nonionic polymers, silicones, siloxanes, polymer emulsions, and nanoparticles.

8. A method according to claim 1 wherein the hair benefit agent and the composition comprising a hair-binding peptide are applied to the hair concomitantly.

9. A method according to claim 1 wherein the hair benefit agent is applied to the hair prior to the application of the composition comprising a hair-binding peptide.

10. A method according to claim 1 wherein the composition comprising a hair-binding peptide is applied to the hair prior to the application of the hair benefit agent.

11. A method according to claim 1 wherein the composition comprising a hair-binding peptide comprises a conjugate comprising a hair-binding peptide coupled to a hair benefit agent.

12. A method according to claim 11 wherein the hair benefit agent is selected from the group consisting of hair colorants and hair conditioners.

13. A method according to claim 11 wherein the hair-binding peptide of the conjugate is covalently bonded to the benefit agent.

14. A method according to claim 1 wherein the hair benefit agent of step (a) is optionally coupled to a hair-binding peptide.

15. A method according to claim 1 wherein the hair-binding peptide is generated combinatorially by a process selected from the group consisting of phage display, yeast display, bacteria display and combinatorial solid phase peptide synthesis.

16. A method according to claim 1 wherein the hair-binding peptide is generated empirically.

17. A method according to claim 16 wherein the empirically generated peptide comprises positively charged amino acids having affinity for hair.

18. A method according to claim 1 or 14 wherein the hair-binding peptide is selected from the group consisting of SEQ ID NOs:

1, 2, 3, 4, 5, 6, 8, 9, 10, 11, 12, 16, 17, 18, 19, 20, 21, and 52.

19. A method according to claim 1 further comprising the step of:

d) reapplying the composition comprising a hair-binding peptide to the hair for a time sufficient for the hair-binding peptide to bind to hair.

20. A method according to claim 1 further comprising the step of:

d) applying a composition comprising a polymeric sealant to the hair.

21. A method according to claim 20 wherein the polymeric sealant is selected from the group consisting of poly(allylamine), polyacrylates, acrylate copolymers, polyurethanes, carbomers, methicones, amodimethicones, polyethylenene glycol, beeswax, and siloxanes.

22. A method for applying a benefit agent to skin comprising the steps of:

a) providing a skin benefit agent having affinity to skin;

b) providing a composition comprising a skin-binding peptide;

c) applying the benefit agent and the composition comprising a skin-binding peptide to skin for a time sufficient for the skin benefit agent and the skin-binding peptide to bind to skin.

23. A method according to claim 22 wherein the skin benefit agent is selected from the group consisting of skin conditioners, dyes, pigments and sunscreens.

24. A method according to claim 23 wherein the skin conditioner is selected from the group consisting of alpha-hydroxy acids, beta-hydroxy acids, polyols, hyaluronic acid, D,L-panthenol, vitamin A palmitate, vitamin E acetate, polysalicylates, sorbitol, silicones, silicone derivatives, lanolin, natural oils, triglyceride esters, propylene glycol, glycerin, glycolic acid, lactic acid, malic acid, citric acid, tartaric acid, glucaric acid, galactaric acid, 3-hydroxyvaleric acid, salicylic acid, titanium dioxide nanoparticles, and 1,3 propanediol.

25. A method according to claim 23 wherein the dye is selected from the group consisting of 4-hydroxypropylamino-3-nitrophenol, 4-amino-3-nitrophenol, 2-amino-6-chloro-4-nitrophenol, 2-nitro-paraphenylenediamine, N,N-hydroxyethyl-2-nitro-phenylenediamine, 4-nitro-indole, 2-nitro-5-glyceryl methylaniline, 3-metylamino-4-nitrophenoxyethanol, 3-nitro-p-hydroxyethylaminophenol, hydroxyanthraquinoneaminopropylmethyl morpholinium methosulfate, Henna, HC Blue 1, HC Blue 2, HC Yellow 4, HC Red 3, HC Red 5, HC Red 7, HC Violet 1, HC Violet 2, HC Blue 7, HC Blue 10, HC Blue 12, HC Yellow 2, HC Yellow 6, HC Yellow 8, HC Yellow 12, HC Orange 2, HC Orange 3, HC Brown 2, D&

C Yellow 1 D&

C Yellow 3, D&

C Blue 1, Disperse Blue 3, Disperse Violet 1, Disperse Orange, Disperse Violet 4, Disperse Black 9, Basic Orange 31, Basic Yellow 57, Basic Yellow 87, HC Yellow No. 9, Basic Blue 26, Basic Blue 7, Basic Blue 99, Basic Violet 14, Basic Violet 2, Basic Brown 16, Basic Brown 17, Basic Red 2, Basic Red 51, Acid Red 33, Brilliant Black 1, eosin derivatives, halogenated fluorescein derivatives and dihydroxyacetone.

26. A method according to claim 23 wherein the pigment is selected from the group consisting of D&

C Red No. 36, D&

C Red No. 30, D&

C Orange No. 17, Green 3 Lake, Ext. Yellow 7 Lake, Orange 4 Lake, Red 28 Lake;

the calcium lakes of D&

C Red Nos. 7, 11, 31 and 34, the barium lake of D&

C Red No. 12, the strontium lake D&

C Red No. 13, the aluminum lakes of FD&

C Yellow No. 5, of FD&

C Yellow No. 6, of FD&

C No. 40, of D&

C Red Nos. 21, 22, 27, and 28, of FD&

C Blue No. 1, of D&

C Orange No. 5, of D&

C Yellow No. 10;

the zirconium lake of D&

C Red No. 33;

Cromophthal®

Yellow, Sunfast®

Magenta, Sunfast®

Blue, iron oxides, calcium carbonate, aluminum hydroxide, calcium sulfate, kaolin, ferric ammonium ferrocyanide, magnesium carbonate, carmine, barium sulfate, mica, bismuth oxychloride, zinc stearate, manganese violet, chromium oxide, titanium dioxide, titanium dioxide nanoparticles, zinc oxide, barium oxide, ultramarine blue, bismuth citrate, hydroxyapatite, zirconium silicate, and carbon black particles.

27. A method according to claim 23 wherein the sunscreen is selected from the group consisting of organic sunscreens and inorganic sunscreens.

28. A method according to claim 27 wherein the organic sunscreen is selected from the group consisting of para-aminobenzoic acid, ethyl para-aminobenzoate, amyl para-aminobenzoate, octyl para-aminobenzoate, ethylhexyl dimethyl para-aminobenzoate, ethylene glycol salicylate, phenyl salicylate, octyl salicylate, benzyl salicylate, butylphenyl salicylate, homomenthyl salicylate, ethylhexyl salicylate, TEA-salicylate, benzyl cinnamate, 2-ethoxyethyl para-methoxycinnamate, ethylhexyl methoxycinnamate, octyl para-methoxycinnamate, glyceryl mono(2-ethylhexanoate) dipara-methoxycinnamate, isopropyl para-methoxycinnamate, urocanic acid, ethyl urocanate, hydroxymethoxybenzophenone, hydroxymethoxybenzophenonesulfonic acid, hydroxymethoxybenzophenonesulfonic acid salts, dihydroxymethoxybenzophenone, sodium dihydroxymethoxybenzophenonedisulfonate, dihydroxybenzophenone, tetrahydroxybenzophenone, 4-tert-butyl-4′

-methoxydibenzoylmethane, phenylbenzimidazole sulfonic acid, 2,4,6-trianilino-p-(carbo-2′

-ethylhexyl-1′

-oxy)-1,3,5-triazine, Octocrylene, menthyl anthranilate, and 2-(2-hydroxy-5-methylphenyl)benzotriazole.

29. A method according to claim 27 wherein the inorganic sunscreen is selected from the group consisting of titanium dioxide, zinc oxide, iron oxide and titanium dioxide nanoparticles.

30. A method according to claim 22 wherein the skin benefit agent and the composition comprising a skin-binding peptide are applied to the skin concomitantly.

31. A method according to claim 22 wherein the skin benefit agent is applied to the skin prior to the application of the composition comprising a skin-binding peptide.

32. A method according to claim 22 wherein the composition comprising a skin-binding peptide is applied to the skin prior to the application of the skin benefit agent.

33. A method according to claim 22 wherein the composition comprising a skin-binding peptide comprises a conjugate comprising a skin-binding peptide coupled to a skin benefit agent.

34. A method according to claim 33 wherein the skin benefit agent is selected from the group consisting of skin colorants and skin conditioners.

35. A method according to claim 33 wherein the skin-binding peptide of the conjugate is covalently bonded to the benefit agent.

36. A method according to claim 22 wherein the skin benefit agent of step (a) is optionally coupled to a skin-binding peptide.

37. A method according to claim 22 or 36 wherein the skin-binding peptide is selected from the group consisting of SEQ ID NOs:

7, 8, 9, 10, 11, and 12.

38. A method according to claim 22 further comprising the step of:

e) reapplying the composition comprising a skin-binding peptide to the skin.

39. A method according to claim 22 further comprising the step of:

e) applying a composition comprising a polymeric sealant to the skin.

40. A method according to claim 39 wherein the polymeric sealant is selected from the group consisting of poly(allylamine), polyacrylates, acrylate copolymers, polyurethanes, carbomers, methicones, amodimethicones, polyethylenene glycol, beeswax, and siloxanes.

41. A hair colorant composition comprising a hair colorant and a hair-binding peptide wherein the colorant and the peptide are not coupled to each other.

42. A hair conditioning composition comprising a hair conditioner and a hair-binding peptide wherein the conditioner and the peptide are not coupled to each other.

43. A skin conditioning composition comprising a skin conditioner and a skin-binding peptide wherein the conditioner and the peptide are not coupled to each other.

44. A skin colorant composition comprising a skin colorant and a skin-binding peptide wherein the colorant and the peptide are not coupled to each other.

45. A hair-binding peptide selected from the group consisting of SEQ ID NOs:

16, 17, 18, 19, 20, and 21.