Self-expanding biodegradable or water-soluble vaso-occlusive devices

• US 20070078480A1
• Filed: 10/04/2005
• Published: 04/05/2007
• Est. Priority Date: 10/04/2005
• Status: Abandoned Application

• Current Assignee: Stryker European Operations Holdings, LLC (Stryker Corporation)
• Original Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Inventors: Belenkaya, Bronislava, Lee, Elaine
• Application Number:
  US11/242,981
• Publication Number:
  US 20070078480A1
• Time in Patent Office: Days
• US Class Current: 606/200
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 17/1219 expandable in contact with liquids
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device
• CPC Class Codes: A61L 31/145 Hydrogels or hydrocolloids
• CPC Class Codes: A61L 31/148 Materials at least partially resorbable by the body

Abstract

This is a device for occluding a space within the body. In particular, the device comprises a self-expanding biodegradable or water-soluble material that is placed within the space to be occluded.

Claims

1. A vaso-occlusive device for placement inside an aneurysm, the device comprising a self-expandable material that is noncovalently cross-linked and degradable or water-soluble.

2. The device of claim 1, wherein the self-expanding material comprises a hydrogel.

3. The device of claim 2, wherein the hydrogel comprises a polysaccharide or mucopolysaccharide.

4. The device of claim 2, wherein the hydrogel comprises a protein.

5. The device of claim 2, wherein the hydrogel comprises carboxy alkyl cellulose.

6. The device of claim 2, wherein the hydrogel comprises a synthetic polymer.

7. The device of claim 1, further comprising an inner member.

8. The device of claim 7, wherein the device has a linear primary configuration prior to deployment and a secondary three-dimensional configuration after deployment.

9. The device of claim 7, wherein the self-expanding material surrounds the inner member at one or more locations.

10. The device of claim 7, wherein the inner member comprises a metal.

11. The device of claim 10, wherein the metal is selected from the group consisting of nickel, titanium, platinum, palladium, rhodium, gold, tungsten, iridium, stainless steel and alloys or combinations thereof.

12. The device of claim 11, wherein the metal is nitinol.

13. The device of claim 7, wherein the self-expanding material is a sheath or a sleeve disposed around the inner member.

14. The device of claim 7, wherein the self-expanding material is coated, dipcoated or spray-dried on the inner member.

15. The device of claim 7, wherein the self-expanding material is coated onto a degradable or nondegradable polymeric or metallic suture, and wherein the sutures are attached to the inner member.

16. The device of claim 15, wherein the sutures are wound or braided around the inner member.

17. The device of claim 7, wherein the self-expanding material comprises one or more fibers.

18. The device of claim 17, wherein the fibers are wound or braided around the inner member.

19. The device of claim 17, wherein the fibers are wound or braided onto a degradable or nondegradable suture, and wherein the sutures are attached to the inner member.

20. The device of claim 17, wherein the fibers are nano or micro fibers.

21. The device of claim 7, wherein the inner member further comprises a detachment junction.

22. The device of claim 21, wherein the detachment junction comprises an electrolytically detachable end adapted to detach from a pusher by imposition of a current on the pusher.

23. The device of claim 1, further comprising an additional component.

24. The device of claim 23, wherein the additional component is bioactive.

25. A method of occluding a body cavity comprising introducing a vaso-occlusive device according to claim 1 into the body cavity.

26. The method of claim 25, wherein the body cavity is an aneurysm.

27. The method of claim 26, wherein the aneurysm is ruptured.

28. The device of claim 23, wherein the additional component causes a delay or deceleration of the expansion of the self-expanding material.