F-18 Labeled Amino Acid Analogs
First Claim
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1. A halogenated amino acid analogue having the general formula:
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Abstract
The present invention relates to Halogenated amino acid analogues for use in diagnosis, which compounds have the general formula
R is (C1-C6)alkyl optionally substituted with thioether or ether oxygen atom when n=0, or a substituted aromatic or heteraromatic ring when n=1-6; and m=0 or 1; and X is a halogen atom. The invention further relates to precursor compounds for these analogues, to a method of preparing these analogues, to a pharmaceutical composition comprising these analogues and to the use of these analogues and compositions in the diagnosis of cancer.
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24 Claims
- 1. A halogenated amino acid analogue having the general formula:
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3-4. -4. (canceled)
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7-8. -8. (canceled)
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12-13. -13. (canceled)
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16-21. -21. (canceled)
Specification