Use of radical-scavenging compounds for treatment and prevention of NO-dependent microcirculation disorders
First Claim
1. A pharmaceutical composition for treating NO-dependent microcirculation disorders comprising dipyridamole or a pharmaceutically acceptable salt thereof in combination with one or more HMG CoA reductase inhibitors.
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Abstract
A method of treatment of the human or non-human animal body for treating NO-dependent microcirculation disorders is disclosed, for example microcirculation disorders caused by metabolic diseases, such as elevated levels of homocystin-homocystein inflammatory reactions or autoimmune diseases, furthermore peripheral microcirculation disorders or microcirculation disorders associated with increased cell fragmentation, which method comprises administering to a human or non-human animal body in need of such treatment an effective amount of a pharmaceutical composition containing a substance which scavenges free radicals, e.g. a pyrimido-pyrimidine selected from Dipyridamole, Mopidamol and the pharmaceutically acceptable salts thereof, and the use such substance for the manufacture of a corresponding pharmaceutical composition, optionally in combination with an agent capable of increasing NO procution.
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Citations
8 Claims
- 1. A pharmaceutical composition for treating NO-dependent microcirculation disorders comprising dipyridamole or a pharmaceutically acceptable salt thereof in combination with one or more HMG CoA reductase inhibitors.
Specification