Dynamic StO2 measurements and analysis
First Claim
1. A method for analyzing data related to tissue oxygenation, comprising the steps of:
- taking an initial measurement to collect data on a tissue chromophore whose light absorption properties depend on the oxygenation state of the tissue;
restricting blood flow for a first predetermined period in the region where the initial measurement was made while continuing to measure the tissue chromophore;
un-restricting the blood flow after the first predetermined period while continuing to measure the tissue chromophore; and
using the data collected during the measurements, automatically determining within the data an ischemia start point and an ischemia end point of the first predetermined period.
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Abstract
A method of analyzing a patient'"'"'s tissue oxygenation capabilities includes measuring a tissue chromophore whose light absorption properties depend on the oxygenation state of the tissue and generating data representative of tissue oxygenation before, during and after a controlled ischemia event. From this data characterizing data, including ischemia onset slope, ischemia onset response time, ischemia recovery slope, ischemia recovery response time or hyperemia is automatically determined. This characterizing data is related to corresponding characterizing data determined from a control population. The relationship may be displayed on a graphical display.
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Citations
52 Claims
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1. A method for analyzing data related to tissue oxygenation, comprising the steps of:
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taking an initial measurement to collect data on a tissue chromophore whose light absorption properties depend on the oxygenation state of the tissue;
restricting blood flow for a first predetermined period in the region where the initial measurement was made while continuing to measure the tissue chromophore;
un-restricting the blood flow after the first predetermined period while continuing to measure the tissue chromophore; and
using the data collected during the measurements, automatically determining within the data an ischemia start point and an ischemia end point of the first predetermined period. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A method of analyzing a patient'"'"'s tissue oxygenation capabilities, comprising the steps of:
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measuring a tissue chromophore whose light absorption properties depend on an oxygenation state of the tissue and generating data representative of the patient'"'"'s tissue oxygenation before, during and after a controlled ischemia event; and
automatically determining from said data characterizing data related to tissue oxygenation. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46)
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47. An apparatus for analyzing a patient'"'"'s tissue oxygenation capabilities, the apparatus comprising:
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a software program for installation on a processor, wherein the software program is adapted to;
input data from measurements of a tissue chromophore whose light absorption properties depend on the oxygenation state of the tissue before, during and after a controlled ischemic event; and
determine from said data characterizing data related to tissue oxygenation. - View Dependent Claims (48, 49, 50, 51, 52)
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Specification