Iontophoresis method and apparatus for systemic delivery of active agents
First Claim
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1. A method for systemic delivery of one or more active agents to a site of pain in a subject by use of an iontophoretic delivery device, the method comprising:
- identifying the site of pain in the subject;
obtaining an iontophoretic delivery device comprising one or more active agents;
activating the delivery device to transdermally transport the one or more active agents through a biological interface of the subject into a circulatory system of the subject; and
delivering the one or more active agents to the site of pain in the subject by means of the circulatory system of the subject;
wherein the one or more active agents are of the -caine class of compounds.
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Abstract
A method and an iontophoretic device are provided for delivery of one or more active agents via a circulatory system of a subject to a site of pain in the subject. In certain aspects, systemic delivery of active agents may alleviate pain at a site in a subject. Active agents may be selected from -caine-type anesthetics or painkillers. The device for delivery of an active agent may include a control unit.
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Citations
23 Claims
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1. A method for systemic delivery of one or more active agents to a site of pain in a subject by use of an iontophoretic delivery device, the method comprising:
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identifying the site of pain in the subject;
obtaining an iontophoretic delivery device comprising one or more active agents;
activating the delivery device to transdermally transport the one or more active agents through a biological interface of the subject into a circulatory system of the subject; and
delivering the one or more active agents to the site of pain in the subject by means of the circulatory system of the subject;
wherein the one or more active agents are of the -caine class of compounds. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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23. An iontophoretic delivery device for use in a method for alleviating pain at a site of pain in a subject by systemic delivery of one of more active agents to the site of pain in the subject, comprising:
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identifying the site of pain in the subject;
obtaining an iontophoretic delivery device comprising one or more active agents;
contacting a location on a biological interface of the subject with the delivery device;
activating the delivery device to transdermally transport the one or more active agents through the biological interface of the subject into a circulatory system of the subject; and
allowing the circulatory system of the subject to deliver the one or more active agents to the site of pain in the subject;
wherein the one or more active agents are of the -caine class of compounds.
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Specification