Iontophoresis apparatus and method for delivery of angiogenic factors to enhance healing of injured tissue
First Claim
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1. An iontophoretic delivery device, comprising:
- one or more angiogenic growth factors, or a composition thereof, wherein the one or more angiogenic growth factors, or the composition thereof, is useful to promote or enhance repair or healing of an injured or damaged tissue, and an electrode selectively operable to drive the one or more angiogenic growth factors, or the composition thereof, from the iontophoretic delivery device.
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Abstract
An iontophoresis device includes an active electrode assembly including an active electrode element and at least one active agent reservoir. Active agents include one or more angiogenic growth factors suitable to promote or enhance healing or repair of injured or damaged tissue.
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Citations
12 Claims
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1. An iontophoretic delivery device, comprising:
- one or more angiogenic growth factors, or a composition thereof, wherein the one or more angiogenic growth factors, or the composition thereof, is useful to promote or enhance repair or healing of an injured or damaged tissue, and an electrode selectively operable to drive the one or more angiogenic growth factors, or the composition thereof, from the iontophoretic delivery device.
- View Dependent Claims (2, 3, 4, 5, 6, 11, 12)
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7. A method for delivering an active agent to or through a biological interface of a subject, using an iontophoretic device comprising an active electrode assembly and a counter electrode assembly, the method comprising:
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physically coupling the active electrode assembly and the counter electrode assembly to the biological interface of the subject; and
electrically coupling the active electrode assembly and the counter electrode assembly to poles of a power source to apply a voltage or current to the active electrode assembly and the counter electrode assembly, wherein the electromotive force or current is applied to transport the active agent to or through the biological interface, and wherein the active agent comprises one or more angiogenic growth factors, or a composition thereof, useful for promoting or enhancing repair or healing of an injured or damaged tissue. - View Dependent Claims (8, 9, 10)
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Specification