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Methods and kits for delivering pharmaceutical agents into the coronary vascular adventitia

  • US 20070100319A1
  • Filed: 12/01/2006
  • Published: 05/03/2007
  • Est. Priority Date: 01/22/2002
  • Status: Abandoned Application
First Claim
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1. A method for distributing a lipid-lowering agent in the adventitial tissue of a living vertebrate host, said method comprising:

  • positioning a microneedle through the wall of a blood vessel so that an aperture of the microneedle is positioned in a perivascular space surrounding the blood vessel; and

    delivering an amount of the lipid-lowering agent into the perivascular space so that the agent distributes substantially completely circumferentially through adventitial tissue surrounding the blood vessel at the site of the microneedle.

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