Compositions of Hoodia Gordonii and Pinolenic Acid Derivatives

• US 20070104805A1
• Filed: 10/31/2006
• Published: 05/10/2007
• Est. Priority Date: 11/01/2005
• Status: Abandoned Application

• Current Assignee: Soft Gel Technologies Incorporated (Kenko Corpo)
• Original Assignee: Soft Gel Technologies Incorporated (Kenko Corpo)
• Inventors: Udell, Ronald
• Application Number:
  US11/554,982
• Publication Number:
  US 20070104805A1
• Time in Patent Office: Days
• US Class Current: 424/725
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 31/202 having three or more double bonds, e.g. linolenic eicosanoids, e.g. leukotrienes A61K31/557
• CPC Class Codes: A61K 31/704 attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin digitoxin A61K31/7048
• CPC Class Codes: A61K 36/15 Pinaceae (Pine family), e.g. pine or cedar
• CPC Class Codes: A61K 36/27 Asclepiadaceae (Milkweed family), e.g. hoya
• CPC Class Codes: A61P 3/04 Anorexiants; Antiobesity agents

Abstract

The present invention is directed to compositions containing a pine nut oil and an extract from the genus Hoodia or Trichocaulon and methods of treatment for weight loss.

Claims

1. A composition comprising an extract of a plant of the genus Pinus and an extract of a plant of the genus Hoodia or Trichocaulon.

2. The composition of claim 1, wherein the extract of the plant of the genus Pinus is from Pinus koraiensis.

3. The composition of claim 1, wherein the extract of the plant of the genus Pinus comprises pinolenic acid or is a derivative of pinolenic acid.

4. The composition of claim 3, wherein the pinolenic acid derivative is a mono-, di-, or triglyceride of pinolenic acid.

5. The composition of claim 3, wherein the pinolenic acid derivative is an ester of pinolenic acid.

6. The composition of claim 1, wherein the extract of the plant of the genus Hoodia is from Hoodia gordonii.

7. The composition of claim 1, wherein the extract of the plant of the genus Hoodia or Trichocaulon comprises a steroidal glycoside or is a derivative of a steroidal glycoside.

8. The composition of claim 7, wherein the steroidal glycoside is 3-0-[-β

-D-thevetopyranosyl-(1->

4)-β

-D-cymaropyranosyl-(1->

4)-β

-D-cymaropyranosyl]-12β

-0-tigloyloxy-14-hydroxy-14β

-pregn-50-en-20-one.

9. The composition of claim 1, wherein the extract of the plant of the genus Pinus is from Pinus koraiensis and the extract of the plant of the genus Hoodia is from Hoodia gordonii.

10. The composition of claim 9, wherein the extract from Pinus koraiensis comprises pinolenic acid or is a derivative of pinolenic acid.

11. The composition of claim 10, wherein the extract from Hoodia gordonii comprises 3-0-[-β

-D-thevetopyranosyl-(1->

4)-β

-D-cymaropyranosyl-(1->

4)-β

-D-cymaropyranosyl]-12β

-0-tigloyloxy-14-hydroxy-14β

-pregn-50-en-20-one.

12. The composition of claim 1, further comprising banaba extract.

13. The composition of claim 1, further comprising a conjugated linoleic acid derivative.

14. The composition of claim 13, wherein the conjugated linoleic acid derivative is conjugated linoleic acid, esters or salts thereof.

15. The composition of claim 1, further comprising a starch blocker.

16. The composition of claim 15, wherein the starch blocker is an alpha amylase inhibitor.

17. The composition of claim 15, wherein the starch blocker is derived from Phaseolis vulgaris.

18. A method to reduce body fat, comprising the step of ingesting a composition comprising the composition as claimed in claim 1.

19. A packaged nutraceutical for reducing body fat, comprising a composition comprising the compositions as claimed in claim 1;

and

instructions for administering said fat reducing composition.

20. A method to increase glucose metabolism, comprising the step of ingesting a composition comprising the composition as claimed in claim 1.

21. A packaged nutraceutical for increasing glucose metabolism, comprising a composition comprising the composition as claimed in claim 1;

and

instructions for administering said glucose metabolism increasing composition.

22. A method to inhibit metabolism of carbohydrates, comprising the step of ingesting a composition comprising the composition as claimed in claim 1.

23. A packaged nutraceutical for inhibiting metabolism of carbohydrates, comprising a composition comprising the composition as claimed in claim 1;

and

instructions for administering said composition.

24. A method for weight loss, comprising the step of ingesting a composition comprising a composition comprising the composition as claimed in claim 1.

25. A packaged nutraceutical for weight loss, comprising a composition comprising a composition comprising the composition as claimed in claim 1;

and

instructions for administering said composition.

26. A method to increase the release of cholecystokinin (CCK), comprising the step of ingesting a composition comprising a composition comprising the composition as claimed in claim 1.

27. A packaged nutraceutical to increase the release of cholecystokinin (CCK), comprising a composition comprising a composition comprising the composition as claimed in claim 1;

and

instructions for administering said composition.

28. A soft gel capsule comprising a composition comprising the composition as claimed in claim 1 encapsulated within said soft gel capsule.