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IRE-1alpha substrates

  • US 20070105123A1
  • Filed: 11/04/2005
  • Published: 05/10/2007
  • Est. Priority Date: 11/04/2005
  • Status: Active Grant
First Claim
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1. A substrate for IRE-1α

  • , comprising an oligonucleotide molecule which consists of (i) an RNA loop comprising a cleavage site for IRE-1α

    ; and

    (ii) a nucleotide stem consisting of 4, 5, 6, 7, 8, 9, or 10 nucleotide base pairs.

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