Method and system for providing basal profile modification in analyte monitoring and management systems

• US 20070106135A1
• Filed: 11/04/2005
• Published: 05/10/2007
• Est. Priority Date: 11/04/2005
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories)
• Inventors: Hayter, Gary, Sloan, Mark
• Granted Patent: US 7,766,829 B2
• Time in Patent Office: Days
• US Class Current: 600/322
• CPC Class Codes: A61B 2560/0223 of calibration, e.g. protocols for calibrating sensors
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61M 2205/3303 Using a biosensor
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2230/201 Glucose concentration
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: G16H 10/40 for data related to laboratory analysis, e.g. patient specimen analysis
• CPC Class Codes: G16H 10/60 for patient-specific data, e.g. for electronic patient records
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 40/67 for remote operation
• CPC Class Codes: G16Z 99/00 Subject matter not provided for in other main groups of this subclass

Abstract

Method and system for providing basal profile modification in insulin therapy for use with infusion devices includes periodically monitoring the analyte levels of a patient for a predetermined period of time in order to determine, based on the monitored analyte levels, an appropriate modification factor to be incorporated into the underlying basal profile which was running at the time the periodic monitoring of the analyte levels were performed.

Claims

1. A method, comprising:

monitoring an analyte level of a patient;

retrieving a predetermined parameter; and

determining a modification to an drug therapy profile based on the monitored analyte level and the predetermined parameter.

2. The method of claim 1 wherein the analyte is glucose.

3. The method of claim 1 wherein the predetermined parameter includes insulin sensitivity, a drug infusion rate, a drug infusion time period, a time period corresponding to the monitored analyte level, a time of day associated with the monitored analyte level, or a loop gain factor.

4. The method of claim 3 wherein the drug infusion rate is a basal profile.

5. The method of claim 1 wherein the monitoring step includes determining the analyte level of the patient at a predetermined time interval.

6. The method of claim 5 wherein the predetermined time interval includes one of 5 minutes, 30 minutes, 1 hour, or 2 hours.

7. The method of claim 1 further including the step of outputting the modification to the drug therapy profile to the patient.

8. The method of claim 1 further including the step of implementing the modification to the drug therapy profile.

9. The method of claim 1 wherein the drug therapy profile includes an insulin infusion profile.

10. A system, comprising:

an analyte monitoring unit; and

a processing unit operatively coupled to the analyte monitoring unit, the processing unit configured to receive a plurality of monitored analyte levels of a patient, and to determine a modification to a drug therapy profile based on the received plurality of monitored analyte levels.

11. The system of claim 10 wherein the analyte monitoring unit includes a sensor unit provided in fluid contact with an analyte of a patient.

12. The system of claim 11 wherein the sensor unit includes a subcutaneous analyte sensor, a transcutaneous analyte sensor, and a transdermal patch sensor.

13. The system of claim 10 wherein the processing unit is operatively coupled to an infusion device.

14. The system of claim 10 wherein the processing unit includes an insulin pump.

15. The system of claim 10 wherein the processing unit is configured to determine the modification based on a pattern in the monitored analyte level.

16. The system of claim 15 wherein the pattern is determined based on the plurality of monitored analyte levels for a predetermined time period.

17. The system of claim 16 wherein the predetermined time period includes one of a 12 hour period, or 24 hour period.

18. The system of claim 10 further including a display unit operatively coupled to the processing unit for displaying the determined modification.