DELIVERY OF AGENTS TO TISSUE
First Claim
1. A system for injecting an injectate into patient, comprising:
- a first pressurizable container for holding the injectate;
a patient interface in fluid connection with the first pressurizable container, the patient interface being adapted to pass the injectate into tissue of the patient;
a powered injector in operative connection with the first pressurizable container to pressurize the injectate;
a controller system in operative connection with powered injector; and
a stereotactic localization frame adapted to be placed in operative connection with the patient interface to assist in controlling localization of the patient interface.
5 Assignments
0 Petitions
Accused Products
Abstract
A system for injecting an injectate into patient includes a first pressurizable container for holding the injectate; a patient interface in fluid connection with the first pressurizable container, the patient interface being adapted to pass the injectate into tissue of the patient; a powered injector in operative connection with the first pressurizable container to pressurize the injectate; a controller system in operative connection with powered injector; and a stereotactic localization frame adapted to be placed in operative connection with the patient interface to assist in controlling localization of the patient interface. A system for processing cells (and/or other injectate components) includes a container and a plunger adapted to be slidably positioned within the container. The system includes at least one inlet port through which a fluid can enter the system and at least one effluent port through which an effluent can exit the system. The plunger section forms a sealing engagement with the inner wall of the container such that rearward motion of the plunger is adapted to draw fluid into the system via the inlet and forward motion of the plunger is adapted to force effluent out of the system via the effluent port.
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Citations
65 Claims
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1. A system for injecting an injectate into patient, comprising:
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a first pressurizable container for holding the injectate;
a patient interface in fluid connection with the first pressurizable container, the patient interface being adapted to pass the injectate into tissue of the patient;
a powered injector in operative connection with the first pressurizable container to pressurize the injectate;
a controller system in operative connection with powered injector; and
a stereotactic localization frame adapted to be placed in operative connection with the patient interface to assist in controlling localization of the patient interface. - View Dependent Claims (2, 3, 4, 5, 6, 7, 9, 10, 11, 12, 13)
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8. The system of claim 8 wherein the at least one property of the injectate is at least one of flow rate or pressure.
- 14. A container adapted to store and transport an injectate, the container being adapted to have a fluid introduced therein and effluent removed therefrom to effect processing of the injectate.
- 25. A method of processing cells prior to delivery thereof comprising the step of contacting the cells with at least one fluid to decrease the concentration of a hibernation solution in which the cells are transported wherein the occurrences of exposure of the cells to non-sterile air is minimized and the duration of any occurrence of exposure to non-sterile air is minimized.
- 31. The method of 30 wherein the container comprises a first port for introduction of the at least one fluid and a second port for removal of effluent.
- 37. A system for use in the processing of cells encompassed in a container, the system comprising at least a first fluid path adapted to introduce at least one fluid into the container and at least a second fluid path adapted to remove effluent from the container.
- 48. A system for processing cells comprising a container and a plunger adapted to be slidably positioned within the container, the system including at least one inlet port through which a fluid can enter the system and at least one effluent port through which an effluent can exit the system, the plunger section forming a sealing engagement with the inner wall of the container such that rearward motion of the plunger is adapted to draw fluid into the system via the inlet and forward motion of the plunger is adapted to force effluent out of the system via the effluent port.
- 62. A plunger for use in connection with a container encompassing cells to effect processing of the cells, the plunger comprising a filter through which fluid can pass but cells cannot pass and a sealing member adapted for form a sealing engagement with an interior wall of the container.
Specification