IMPLANTABLE MEDICAL DEVICE WITH CONSTRAINED EXPANSION

• US 20070106372A1
• Filed: 10/10/2006
• Published: 05/10/2007
• Est. Priority Date: 05/19/2003
• Status: Active Grant

• Current Assignee: Cook Medical Technologies, LLC (Cook Group Incorporated)
• Original Assignee: Cook Incorporated (Cook Group Incorporated)
• Inventors: Osborne, Thomas, Flagle, Jacob, Case, Brian, Hoffa, Andrew, Garrison, Michael
• Granted Patent: US 7,955,376 B2
• Time in Patent Office: Days
• US Class Current: 623/1.240
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2475 Venous valves
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2230/0026 trapezoidal
• CPC Class Codes: A61F 2230/0095 Saddle-shaped

Abstract

Medical devices for implantation in a body vessel are provided. A medical device according to the invention comprises a support structure and one or more graft members comprising a valve portion and a constraining portion. The support structure has a first, unexpanded configuration and a second, expanded configuration. The constraining portion is adapted to substantially prevent the support structure from achieving the second, expanded configuration. The valve portion is adapted to permit fluid flow through a body vessel in a first direction and substantially prevent fluid flow through the vessel in a second, opposite direction.

Claims

1. A medical device for implantation in a body vessel, comprising:

a support structure having a first, unexpanded configuration and a second, expanded configuration; and

a graft member connected to the support structure and comprising a valve portion and a constraining portion, the constraining portion sized to be drawn taught as the support structure expands from the first configuration to the second configuration and the valve portion adapted to permit fluid flow through said body vessel in a first direction and substantially prevent fluid flow through said body vessel in a second, opposite direction.

2. The medical device according to claim 1, wherein the valve portion has a first maximum width and the constraining portion has a second maximum width;

and

wherein the first maximum width is greater than the second maximum width.

3. The medical device according to claim 2, wherein the graft member includes a transition portion disposed between the valve portion and the constraining portion, the transition portion having a width that tapers from the first maximum width to the second maximum width.

4. The medical device according to claim 3, further comprising a second graft member connected to the support structure and comprising a second valve portion and a second constraining portion.

5. The medical device according to claim 4, wherein the second graft member includes a second transition portion disposed between the second valve portion and the second constraining portion.

6. The medical device according to claim 5, wherein the first and second valve portions cooperatively define a coaptation region.

7. The medical device according to claim 1, wherein the valve portion defines a first edge and the constraining portion defines a second edge;

and

wherein the first and second edges cooperatively define an opening.

8. The medical device according to claim 7, wherein the valve portion and constraining portion comprise separate members.

9. The medical device according to claim 1, wherein the graft member comprises an extracellular matrix material.

10. The medical device according to claim 1, wherein the graft member comprises small intestine submucosa.

11. A medical device for implantation in a body vessel, comprising:

a support structure having a first, unexpanded configuration and a second, expanded configuration;

a first graft member connected to the support structure and sized to be drawn taught as the support structure expands from the first configuration to the second configuration; and

a second graft member adapted to permit fluid flow through said body vessel in a first direction and substantially prevent fluid flow through said body vessel in a second, opposite direction.

12. The medical device according to claim 11, wherein the first graft member defines a first edge and the second graft member defines a second edge;

and

wherein the first and second edges cooperatively define an opening.

13. The medical device according to claim 11, further comprising a third graft member connected to the support frame, the third graft member sized to be drawn taught as the support structure expands from the first configuration to the second configuration.

14. The medical device according to claim 13, further comprising a fourth graft member connected to the support frame, the fourth graft member sized to be less than taught when the third graft member is drawn taught and adapted to cooperate with the first graft member to permit fluid flow through said body vessel in a first direction and to substantially prevent fluid flow through said body vessel in a second, opposite direction.

15. The medical device according to claim 11, wherein at least one of the first and second graft members comprises an extracellular matrix material.

16. The medical device according to claim 11, wherein at least one of the first and second graft members comprises small intestine submucosa.

17. A medical device for implantation in a body vessel, comprising a graft member connected to an expandable support frame, the graft member including a taught portion adapted to constrain expansion of the support frame and a non-taught portion adapted to selectively permit and substantially prevent fluid flow through said body vessel.

18. The medical device according to claim 17, wherein the non-taught portion has a maximum width that is greater than a maximum width of the taught portion.

19. The medical device according to claim 17, wherein the support frame comprises a stent.

20. The medical device according to claim 17, wherein the taught portion at least partially defines an opening adapted to permit a controlled amount of fluid flow through said body vessel.