Medical articles having enhanced therapeutic agent binding
First Claim
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1. A medical article comprising (a) a fiber having a diameter of 10 microns or less, said fiber comprising a polymeric region having a first charge, and (b) a charged therapeutic agent having a second charge that is opposite in sign to that of said first charge that is bound to said fiber.
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Abstract
According to an aspect of the present invention, medical articles are provided which comprise the following (a) a polymeric region having a first charge, and (b) a charged therapeutic agent having a second charge that is opposite in sign to that of the first charge. In certain beneficial embodiments, the medical articles are high surface area articles, for example, articles formed using small diameter (e.g., 10 microns or less) fibers.
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37 Claims
- 1. A medical article comprising (a) a fiber having a diameter of 10 microns or less, said fiber comprising a polymeric region having a first charge, and (b) a charged therapeutic agent having a second charge that is opposite in sign to that of said first charge that is bound to said fiber.
Specification