Deposition of discrete nanoparticles on an implant surface
First Claim
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1. A method of forming an implant to be implanted into living bone, the method comprising the acts of:
- roughening at least a portion of the implant surface to produce a microscale roughened surface; and
depositing discrete nanoparticles on the roughened surface though a one-step process of exposing the roughened surface to a solution including the nanoparticles, the nanoparticles comprising a material having a property that promotes osseointegration.
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Abstract
A method of forming an implant to be implanted into living bone is disclosed. The method comprises the act of roughening at least a portion of the implant surface to produce a roughened surface. The method further comprises the act of depositing discrete nanoparticles on the roughened surface though a one-step process of exposing the roughened surface to a solution. The nanoparticles comprise a material having a property that promotes osseointegration.
117 Citations
36 Claims
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1. A method of forming an implant to be implanted into living bone, the method comprising the acts of:
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roughening at least a portion of the implant surface to produce a microscale roughened surface; and
depositing discrete nanoparticles on the roughened surface though a one-step process of exposing the roughened surface to a solution including the nanoparticles, the nanoparticles comprising a material having a property that promotes osseointegration. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A method of forming a dental implant made of a titanium or titanium alloy, the method comprising the acts of:
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etching at least a threaded bottom portion of the implant to remove a native oxide layer;
acid etching the threaded bottom portion to form a roughened surface having a substantially uniform array of microscale irregularities having peak-to-valley heights not greater than about 20 microns; and
without pretreating the roughened surface, depositing discrete hydroxyapatite nanocrystals on the roughened surface by exposure to a solution comprising 2-methoxyethanol solvent and the hydroxyapatite nanocrystals. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32)
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- 33. A method of forming an implant to be implanted into living bone, the method comprising the act of depositing discrete nanoparticles on the surface of the implant though a one-step process of exposing the surface to a solution, the nanoparticles comprising a material having a property that promotes osseointegration.
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36. A method of forming an implant to be implanted into living bone, the method comprising the acts of:
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providing an implant;
depositing discrete nanoparticles on the surface of the implant though a one-step process of exposing the surface to a solution, the nanoparticles comprising a material having a property that promotes osseointegration;
rinsing the implant; and
drying the implant.
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Specification