Wound care system

• US 20070118096A1
• Filed: 11/21/2006
• Published: 05/24/2007
• Est. Priority Date: 11/21/2005
• Status: Active Grant

• Current Assignee: Phase One Health, LLC
• Original Assignee: Pioneer Technology, LLC
• Inventors: Fisher, Jack, Smith, David, Porter, Robert, Bohman, David, Smith, Joshua, Andrews, Thomas
• Granted Patent: US 7,648,488 B2
• Time in Patent Office: Days
• US Class Current: 604/541
• CPC Class Codes: A61B 5/145 Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissuemeasuring of blood pressure or blood flow A61B5/02; non-radiation detecting or locating of foreign bodies in blood A61B5/06
• CPC Class Codes: A61B 5/445 Evaluating skin irritation or skin trauma, e.g. rash, eczema, wound, bed sore
• CPC Class Codes: A61F 2013/0017 possibility of applying fluid
• CPC Class Codes: A61F 2013/0097 oxygen content
• CPC Class Codes: A61M 1/915 Constructional details of the pressure distribution manifold
• CPC Class Codes: A61M 1/94 with gas supply means
• CPC Class Codes: A61M 1/96 Suction control thereof
• CPC Class Codes: A61M 1/966 having a pressure sensor on or near the dressing
• CPC Class Codes: A61M 1/982 with means for detecting level of collected exudate
• CPC Class Codes: A61M 2205/3344 Measuring or controlling pressure at the body treatment site
• CPC Class Codes: A61M 2205/3561 local, e.g. within room or hospital
• CPC Class Codes: A61M 2205/3592 using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 35/30 Gas therapy for therapeutic treatment of the skin

Abstract

Disclosed is an apparatus for the treatment of a wound on a patient. The apparatus is capable of administering localized negative pressure therapy to the wound using a negative pressure source and a drain line for removing exudate from the wound. The apparatus is also capable of administering localized hyperbaric fluid therapy to the wound using a fluid source and a supply line for supplying fluid to the wound.

Claims

1. A wound treatment apparatus comprising:

a drain line configured for attachment to a negative pressure source and for removing exudate from the wound;

a supply line configured for attachment to a fluid source and for supplying fluid to the wound;

a controller configured to;

cause negative pressure therapy to be administered to the wound via the drain line, and

cause hyperbaric fluid therapy to be administered to the wound at an absolute pressure of at least approximately 1.5 atmospheres via the supply line.

2. The wound treatment apparatus of claim 1, wherein the controller is further configured to cause negative pressure therapy and hyperbaric fluid therapy to be administered intermittently.

3. The wound treatment apparatus of claim 1, wherein the controller is further configured to cause negative pressure therapy to be administered for a first time period and hyperbaric fluid therapy to be administered for a second time period, and wherein the first time period is approximately two to three times as long as the second time period.

4. The wound treatment apparatus of claim 1, wherein the controller is configured to cause hyperbaric fluid therapy to be administered immediately following the cessation of the administration of negative pressure therapy and wherein the controller is configured to cause negative pressure therapy to be administered immediately following the cessation of the administration of hyperbaric fluid therapy.

5. The wound treatment apparatus of claim 1 wherein the controller is further configured to cause negative pressure therapy to be administered for approximately 20 seconds to approximately 180 seconds.

6. The wound treatment apparatus of claim 1 wherein the controller is further configured to cause hyperbaric fluid therapy to be administered for approximately 10 seconds to approximately 60 seconds.

7. The wound treatment apparatus of claim 1, wherein the controller is further configured to selectively cause the administration of only negative pressure therapy or only hyperbaric fluid therapy.

8. The wound treatment apparatus of claim 7, wherein the negative pressure therapy or hyperbaric fluid therapy is administered intermittently.

9. The wound treatment apparatus of claim 1, wherein the wound is subject to an absolute pressure of from approximately 0 mmHg to approximately 300 mmHg during the administration of negative pressure therapy.

10. The wound treatment apparatus of claim 9, wherein the wound is subject to an absolute pressure of from approximately 60 mmHg to approximately 160 mmHg during the administration of negative pressure therapy.

11. The wound treatment apparatus of claim 1, wherein the wound is subject to an absolute pressure of from approximately 1.5 atmospheres to approximately 3 atmospheres during the administration of hyperbaric fluid therapy.

12. The wound treatment apparatus of claim 1, wherein the drain line is configured for attachment to a hospital room suction line.

13. The wound treatment apparatus of claim 1, wherein the supply line is configured for attachment to a hospital room oxygen line.

14. The wound treatment apparatus of claim 1, wherein a hospital bed comprises the controller.

15. The wound treatment apparatus of claim 1, wherein the fluid supplied to the wound comprises at least one of:

oxygen or humidified oxygen.

16. The wound treatment apparatus of claim 1 further comprising a humidification device operatively connected to the supply line.

17. The wound treatment apparatus of claim 16, wherein the humidification device is configured to humidify oxygen before the oxygen is administered to the wound.

18. The wound treatment apparatus of claim 17, wherein the humidification device is configured increase the temperature at the wound.

19. The wound treatment apparatus of claim 15, wherein the oxygen or humidified oxygen is administered at approximately 0.1 liters per minute to approximately 3 liters per minute.

20. The wound treatment apparatus of claim 16, wherein the oxygen or humidified oxygen is administered at approximately 1 liter per minute to approximately 2 liters per minute.

21. The wound treatment apparatus of claim 1, wherein the fluid supplied to the wound comprises at least one non-oxygen drug.

22. The wound treatment apparatus of claim 21, wherein the non-oxygen drug is supplied in powder form via gas.

23. The wound treatment apparatus of claim 21, wherein the non-oxygen drug is supplied in vapor form via humidified gas.

24. The wound treatment apparatus of claim 21, wherein the non-oxygen drug is supplied via a humidification device operatively connected to the supply line.

25. The wound treatment apparatus of claim 1, further comprising a negative pressure source and a fluid source.

26. The wound treatment apparatus of claim 25, further comprising a casing surrounding both the negative pressure source and the fluid source.

27. The wound treatment apparatus of claim 25, wherein the negative pressure source is a vacuum.

28. The wound treatment apparatus of claim 25, wherein the fluid source is an oxygen concentrator.

29. The wound treatment apparatus of claim 25, wherein the fluid source is an oxygen canister.

30. The wound treatment apparatus of claim 25, wherein the negative pressure source and fluid source share a power supply.

31. The wound treatment apparatus of claim 25, wherein the fluid source is configured to supply a constant flow of fluid and the controller is configured to cause the negative pressure source to operate intermittently such that negative pressure therapy is administered to the wound when the negative pressure source is on and hyperbaric fluid therapy is administered to the wound when the negative pressure source is off.

32. The wound treatment apparatus of claim 1, further comprising a diffusion sensor to measure diffusion of fluid into the wound.

33. The wound treatment apparatus of claim 32, wherein the diffusion sensor is a transcutaneous oxygen sensor.

34. The wound treatment apparatus of claim 32, wherein the diffusion sensor is operatively connected to the controller and the controller is further configured to adjust at least one of the negative pressure therapy or the hyperbaric fluid therapy in response to information received from the diffusion sensor.

35. The wound treatment apparatus of claim 34, wherein the controller is configured to cause an increase in at least one of the fluid flow rate or the pressure at the wound during hyperbaric fluid therapy in response to information received from the diffusion sensor indicating that the fluid diffusion rate is below a desired level.

36. The wound treatment apparatus of claim 34, wherein the controller is configured to cause an increase in the duration of the administration of hyperbaric fluid therapy relative to the negative pressure therapy in response to information received from the diffusion sensor indicating that the fluid diffusion rate is below a desired level.

37. The wound treatment apparatus of claim 34, wherein the controller is configured to cause a decrease in the duration of the administration of negative pressure therapy relative to the hyperbaric fluid therapy in response to information received from the diffusion sensor indicating that the fluid diffusion rate is below a desired level.

38. The wound treatment apparatus of claim 1, further comprising a pressure sensor to measure pressure at the wound.

39. The wound treatment apparatus of claim 38, wherein the pressure sensor is operatively connected to the controller and the controller is further configured to adjust at least one of the negative pressure therapy or the hyperbaric fluid therapy in response to information received from the pressure sensor.

40. The wound treatment apparatus of claim 1, further comprising a heating element operatively connected to the controller and engaging the wound, wherein the controller is further configured to control the heating element to maintain a temperature at the wound above approximately 98 degrees Fahrenheit and below the combustion temperature of the fluid administered during hyperbaric fluid therapy.

41. The wound treatment apparatus of claim 40, wherein a humidification device operatively connected to the supply line comprises the heating element.

42. The wound treatment apparatus of claim 1 wherein the controller is further configured to selectively cause the cessation of one of the negative pressure therapy or the hyperbaric fluid therapy without causing the cessation of the other of the negative pressure therapy or the hyperbaric fluid therapy.

43. The wound treatment apparatus of claim 1, further comprising a collection device operatively connected to the drain line to collect exudate from the wound.

44. The wound treatment apparatus of claim 43, wherein the collection device comprises a sensor for indicating the amount of exudate in the collection device.

45. The wound treatment apparatus of claim 44, wherein the collection device sensor is operatively connected to the controller and the controller is further configured to stop the administration of negative pressure therapy upon receiving information from the collection device sensor indicating that the collection device is full.

46. The wound treatment apparatus of claim 1, further comprising a mechanical pressure regulator connected to the supply line.

47. The wound treatment apparatus of claim 46, wherein the mechanical pressure regulator is configured to actuate when the pressure at the regulator exceeds a set threshold whereby the actuation of the mechanical pressure regulator causes a reduction of the supply line pressure.

48. The wound treatment apparatus of claim 47, wherein the mechanical pressure regulator is further configured to maintain a reduced pressure within the supply line following the actuation of the mechanical pressure regulator.

49. The wound treatment apparatus of claim 1, wherein at least part of the drain line and at least part of the supply line are formed by a multi-lumen tube.

50. The wound treatment apparatus of claim 1, further comprising a dressing to cover the wound and engage the supply line and the drain line.

51. The wound treatment apparatus of claim 50, wherein the supply line and drain line are merged into a single lumen tube for engaging the dressing.

52. The wound treatment apparatus of claim 50, wherein the dressing comprises packing material positioned between the drain line and the wound.

53. The wound treatment apparatus of claim 52, wherein the packing material is anti-microbial gauze saturated with saline.

54. The wound treatment apparatus of claim 50, wherein the dressing comprises packing material positioned between the drain line and a sealing material opposite the wound.

55. The wound treatment apparatus of claim 50, wherein the dressing comprises a pliable adhesive material molded onto the patient'"'"'s skin around the perimeter of the wound to form a gasket between the patient'"'"'s skin and a sealing material opposite the skin.

56. The wound treatment apparatus of claim 55, wherein the pliable adhesive material is molded around and engages the supply line and the drain.

57. The wound treatment apparatus of claim 50, wherein the dressing comprises a sealing material covering the wound.

58. A wound treatment apparatus comprising:

a drain line configured for attachment to a negative pressure source and for removing exudate from the wound;

a supply line configured for attachment to a fluid source and for supplying fluid to the wound;

a controller configured to;

cause negative pressure therapy to be administered to the wound for a first time period via the drain line, and

cause hyperbaric fluid therapy to be administered to the wound for a second time period via the supply line,

wherein the first time period is approximately two to three times as long as the second time period.

59. The wound treatment apparatus of claim 58, wherein the controller is configured to cause hyperbaric fluid therapy to be administered immediately following the cessation of the administration of negative pressure therapy and wherein the controller is configured to cause negative pressure therapy to be administered immediately following the cessation of the administration of hyperbaric fluid therapy.

60. The wound treatment apparatus of claim 58 wherein the controller is further configured to cause negative pressure therapy to be administered for approximately 20 seconds to approximately 180 seconds.

61. The wound treatment apparatus of claim 58 wherein the controller is further configured to cause hyperbaric fluid therapy to be administered for approximately 10 seconds to approximately 60 seconds.

62. The wound treatment apparatus of claim 58, wherein the controller is further configured to selectively cause the administration of only negative pressure therapy or only hyperbaric fluid therapy.

63. The wound treatment apparatus of claim 62, wherein the negative pressure therapy or hyperbaric fluid therapy is administered intermittently.

64. The wound treatment apparatus of claim 58, wherein the wound is subject to an absolute pressure of from approximately 0 mmHg to approximately 300 mmHg during the administration of negative pressure therapy.

65. The wound treatment apparatus of claim 64, wherein the wound is subject to an absolute pressure of from approximately 60 mmHg to approximately 160 mmHg during the administration of negative pressure therapy.

66. The wound treatment apparatus of claim 58, wherein the wound is subject to an absolute pressure of from approximately 1.5 atmospheres to approximately 3 atmospheres during the administration of hyperbaric fluid therapy.

67. The wound treatment apparatus of claim 58, wherein the fluid supplied to the wound comprises at least one of:

oxygen or humidified oxygen.

68. A portable wound treatment apparatus comprising:

a negative pressure source configured for operative engagement with a wound dressing via a drain line;

a fluid source configured for operative engagement with a wound dressing via a supply line;

a controller configured to;

cause negative pressure therapy to be administered to the wound, and

cause hyperbaric fluid therapy to be administered to the wound at an absolute pressure of at least approximately 1.5 atmospheres; and

a housing configured to house the negative pressure source, the fluid source and the controller.

69. The portable wound treatment apparatus of claim 68, further comprising a power source for supplying power to at least one of the negative pressure source and the fluid source, wherein the housing is further configured to house the power source.

70. The portable wound treatment apparatus of claim 69, wherein the fluid source is an oxygen concentrator, the negative pressure source is suction device and the power source is a rechargeable battery.

71. The portable wound treatment apparatus of claim 68, further comprising:

a drain line configured for attachment to a negative pressure source and for removing exudate from the wound; and

a supply line configured for attachment to a fluid source and for supplying fluid to the wound.

72. The portable wound treatment apparatus of claim 71, further comprising a collection device operatively connected to the drain line to collect exudate from a wound.

73. The portable wound treatment apparatus of claim 71, wherein at least part of the drain line and at least part of the supply line are formed by a multi-lumen tube.

74. The portable wound treatment apparatus of claim 68 wherein the controller is further configured to cause negative pressure therapy to be administered immediately following the administration of hyperbaric fluid therapy and to cause hyperbaric fluid therapy to be administered immediately following the administration of negative pressure therapy.

75. The portable wound treatment apparatus of claim 68 wherein the controller is further configured to cause negative pressure therapy to be administered for approximately 20 to approximately 180 seconds and to cause hyperbaric fluid therapy to be administered for approximately 10 to approximately 60 seconds.

76. The portable wound treatment apparatus of claim 68, wherein the wound is subject to an absolute pressure of from approximately 60 mmHg to approximately 160 mmHg during the administration of negative pressure therapy.

77. The portable wound treatment apparatus of claim 68, wherein the wound is subject to an absolute pressure of from approximately 1.5 atmospheres to approximately 3 atmospheres during the administration of hyperbaric fluid therapy.

78. The portable wound treatment apparatus of claim 68, wherein the fluid supplied to the wound comprises at least one of:

oxygen or humidified oxygen.

79. The portable wound treatment apparatus of claim 68, further comprising a dressing to cover the wound and engage the supply line and the drain line.

80. A portable wound treatment apparatus comprising:

a negative pressure source configured for operative engagement with a wound dressing via a drain line;

a fluid source configured for operative engagement with a wound dressing via a supply line;

a controller configured to;

cause negative pressure therapy to be administered for a to the wound first time period, and

cause hyperbaric fluid therapy to be administered to the wound for a second time period,

wherein the first time period is approximately two to three times as long as the second time period; and

a housing configured to house the negative pressure source, the fluid source and the controller.

81. The portable wound treatment apparatus of claim 80, further comprising a power source for supplying power to at least one of the negative pressure source and the fluid source, wherein the housing is further configured to house the power source.

82. The portable wound treatment apparatus of claim 80, wherein the fluid source is an oxygen concentrator, the negative pressure source is suction device and the power source is a rechargeable battery.

83. The portable wound treatment apparatus of claim 80, further comprising:

a drain line configured for attachment to a negative pressure source and for removing exudate from the wound; and

a supply line configured for attachment to a fluid source and for supplying fluid to the wound.

84. The portable wound treatment apparatus of claim 83, further comprising a collection device operatively connected to the drain line to collect exudate from a wound.

85. The portable wound treatment apparatus of claim 83, wherein at least part of the drain line and at least part of the supply line are formed by a multi-lumen tube.

86. The portable wound treatment apparatus of claim 80 wherein the controller is further configured to cause negative pressure therapy to be administered immediately following the administration of hyperbaric fluid therapy and to cause hyperbaric fluid therapy to be administered immediately following the administration of negative pressure therapy.

87. The portable wound treatment apparatus of claim 80 wherein the first time period is approximately 20 seconds to approximately 180 seconds and second time period is approximately 10 seconds to approximately 60 seconds.

88. The portable wound treatment apparatus of claim 80, wherein the wound is subject to an absolute pressure of from approximately 60 mmHg to approximately 160 mmHg during the administration of negative pressure therapy.

89. The portable wound treatment apparatus of claim 80, wherein the wound is subject to an absolute pressure of from approximately 1.5 atmospheres to approximately 3 atmospheres during the administration of hyperbaric fluid therapy.

90. The portable wound treatment apparatus of claim 80, wherein the fluid supplied to the wound comprises at least one of:

oxygen or humidified oxygen.

91. The portable wound treatment apparatus of claim 80, further comprising a dressing to cover the wound and engage the supply line and the drain line.

92. A method for treating a wound comprising:

applying to the wound a dressing that engages a supply line and a drain line;

connecting the supply line to a fluid source;

connecting the drain line to a negative pressure source;

administering negative pressure therapy to the wound via the drain line; and

administering hyperbaric fluid therapy to the wound at an absolute pressure of at least 1.5 atmospheres via the supply line.

93. The method of claim 92, wherein the negative pressure therapy and the hyperbaric fluid therapy are administered intermittently.

94. The method of claim 92, wherein negative pressure therapy is administered immediately following the administration of hyperbaric fluid therapy and hyperbaric fluid therapy is administered immediately following the administration of negative pressure therapy.

95. The method of claim 92, wherein the negative pressure therapy is administered for a first time period and the hyperbaric fluid therapy is administered for a second time period, and wherein the first time period is approximately two to three times as long as the second time period.

96. The method of claim 92, wherein negative pressure therapy is administered for approximately 20 to approximately 180 seconds and hyperbaric fluid therapy is administered for approximately 10 to approximately 60 seconds.

97. The method of claim 92, wherein the wound is subject to an absolute pressure of from approximately 60 mmHg to approximately 160 mmHg during the administration of negative pressure therapy.

98. The method of claim 92, wherein the wound is subject to an absolute pressure of from approximately 1.5 atmospheres to approximately 3 atmospheres during the administration of hyperbaric fluid therapy.

99. The method of claim 92, wherein administering hyperbaric fluid therapy comprises supplying fluid to the wound wherein the fluid comprises at least one of:

oxygen or humidified oxygen.

100. The method of claim 99, wherein the oxygen or humidified oxygen is administered at approximately 0.1 liters per minute to approximately 3 liters per minute.

101. The method of claim 99, wherein the oxygen or humidified oxygen is administered at approximately 1 liter per minute to approximately 2 liters per minute.

102. The method of claim 93, wherein administering hyperbaric fluid therapy comprises supplying fluid to the wound, wherein the fluid comprises at least one non-oxygen drug.

103. The method of claim 102, wherein the non-oxygen drug is supplied in powder form via gas.

104. The method of claim 102, wherein the non-oxygen drug is supplied in vapor form via humidified gas.

105. The method of claim 102, wherein the non-oxygen drug is supplied via a humidification device operatively connected to the supply line.

106. The method of claim 92, wherein the fluid source is configured to supply a constant flow of fluid, wherein administering negative pressure therapy comprises activating the negative pressure source and wherein administering hyperbaric fluid therapy comprises deactivating the negative pressure source.

107. The method of claim 92, wherein administering negative pressure therapy comprises activating the negative pressure source and reducing the flow of fluid from the fluid source and wherein administering hyperbaric fluid therapy comprises deactivating the negative pressure source and increasing the flow of fluid from the hyperbaric fluid source.

108. The method of claim 92, further comprising receiving information from a diffusion sensor relating to the diffusion into the wound of fluid supplied at least during hyperbaric fluid therapy.

109. The method of claim 108, further comprising using the information received from the diffusion sensor to adjust at least one of the negative pressure therapy or the hyperbaric oxygen therapy.

110. The method of claim 108, further comprising increasing the fluid flow rate or the pressure at the wound during hyperbaric fluid therapy in response to information received from the diffusion sensor indicating that the fluid diffusion rate is below a desired level.

111. The method of claim 108, further comprising increasing the duration of the administration of hyperbaric fluid therapy relative to the negative pressure therapy in response to information received from the diffusion sensor indicating that the fluid diffusion rate is below a desired level.

112. A method for treating a wound comprising:

applying to the wound a dressing that engages a supply line and a drain line;

connecting the supply line to a fluid source;

connecting the drain line to a negative pressure source;

administering negative pressure therapy to the wound via the drain line for a first time period;

administering hyperbaric fluid therapy to the wound via the supply line for a second time period;

wherein the first time period is approximately two to three times as long as the second time period.

113. The method of claim 112, wherein the negative pressure therapy and the hyperbaric fluid therapy are administered intermittently.

114. The method of claim 112, wherein negative pressure therapy is administered immediately following the administration of hyperbaric fluid therapy and hyperbaric fluid therapy is administered immediately following the administration of negative pressure therapy.

115. The method of claim 112, negative pressure therapy is administered for approximately 20 to approximately 180 seconds and hyperbaric fluid therapy is administered for approximately 10 to approximately 60 seconds.

116. The method of claim 112, wherein the wound is subject to an absolute pressure of from approximately 60 mmHg to approximately 160 mmHg during the administration of negative pressure therapy.

117. The method of claim 112, wherein the wound is subject to an absolute pressure of from approximately 1.5 atmospheres to approximately 3 atmospheres during the administration of hyperbaric fluid therapy.

118. The method of claim 112, wherein administering hyperbaric fluid therapy comprises supplying fluid to the wound wherein the fluid comprises at least one of:

oxygen or humidified oxygen.

119. The method of claim 118, wherein the oxygen or humidified oxygen is administered at approximately 0.1 liters per minute to approximately 3 liters per minute.

120. The method of claim 118, wherein the oxygen or humidified oxygen is administered at approximately 1 liter per minute to approximately 2 liters per minute.

121. The method of claim 118, wherein administering hyperbaric fluid therapy comprises supplying fluid to the wound, wherein the fluid comprises at least one non-oxygen drug.

122. The method of claim 121, wherein the non-oxygen drug is supplied in powder form via gas.

123. The method of claim 121, wherein the non-oxygen drug is supplied in vapor form via humidified gas.

124. The method of claim 121, wherein the non-oxygen drug is supplied via a humidification device operatively connected to the supply line.

125. The method of claim 112, wherein the fluid source is configured to supply a constant flow of fluid, wherein administering negative pressure therapy comprises activating the negative pressure source and wherein administering hyperbaric fluid therapy comprises deactivating the negative pressure source.

126. The method of claim 112, wherein administering negative pressure therapy comprises activating the negative pressure source and reducing the flow of fluid from the fluid source and wherein administering hyperbaric fluid therapy comprises deactivating the negative pressure source and increasing the flow of fluid from the hyperbaric fluid source.

127. The method of claim 112, further comprising receiving information from a diffusion sensor relating to the diffusion into the wound of fluid supplied at least during hyperbaric fluid therapy.

128. The method of claim 128, further comprising using the information received from the diffusion sensor to adjust at least one of the negative pressure therapy or the hyperbaric oxygen therapy.

129. The method of claim 128, further comprising increasing the fluid flow rate or the pressure at the wound during hyperbaric fluid therapy in response to information received from the diffusion sensor indicating that the fluid diffusion rate is below a desired level.

130. The method of claim 128, further comprising increasing the duration of the administration of hyperbaric fluid therapy relative to the negative pressure therapy in response to information received from the diffusion sensor indicating that the fluid diffusion rate is below a desired level.

131. A method for preparing a wound dressing comprising:

inserting packing material into the wound;

inserting open ends of a supply line and a drain line into the wound;

molding a pliable adhesive around the perimeter of the wound such that the adhesive separates the supply line from the skin surrounding the wound and such that the adhesive separates the drain line from the skin surrounding the wound;

molding another piece of pliable adhesive over the supply line and the drain line; and

placing sealing material over the wound, the packing material, the supply line, the drain line and the adhesive such that the sealing material adheres to both the adhesive and the skin surrounding the adhesive.

132. The method of claim 131, further comprising inserting a protective mesh prior to inserting the packing material.

133. The method of claim 131, wherein the packing material comprises anti-microbial gauze saturated with saline.

134. The method of claim 131, wherein a multi-lumen tube forms the supply line and the drain line.

135. The method of claim 131, wherein inserting packing into the wound comprises inserting packing below and above the supply line and the drain line.

136. The method of claim 131, wherein inserting open ends of a supply line and a drain line into the wound comprises inserting into the wound a drain connected to the supply and drain line.

137. The method of claim 131, wherein the pliable adhesive is a cohesive seal.

138. A method for treating a wound comprising:

applying to the wound a dressing that engages a supply line and a drain line;

connecting the supply line to a fluid source;

connecting the drain line to a negative pressure source;

administering negative pressure therapy to the wound via the drain line for a first time period;

following the administration of negative pressure therapy, administering hyperbaric fluid therapy to the wound via the supply line for no more than 30 minutes; and

following the administration of hyperbaric fluid therapy, administering negative pressure therapy to the wound via the drain line.

139. A wound treatment apparatus comprising:

a drain line configured for attachment to a negative pressure source and for removing exudate from the wound;

a supply line configured for attachment to a fluid source and for supplying fluid to the wound;

a controller configured to;

cause negative pressure therapy to be administered to the wound via the drain line, and

cause hyperbaric fluid therapy to be administered to the wound at via the supply line,

wherein the administration of negative pressure therapy and hyperbaric fluid therapy is cyclical, and

wherein hyperbaric fluid therapy is administered to the wound for no more than 30 minutes during each cycle.