Composite stent with regioselective material

• US 20070118212A1
• Filed: 12/18/2006
• Published: 05/24/2007
• Est. Priority Date: 06/29/2001
• Status: Active Grant

• Current Assignee: Advanced Cardiovascular Systems Incorporated
• Original Assignee: Advanced Cardiovascular Systems Incorporated
• Inventors: Hossainy, Syed, Mirzaee, Daryush, Padilla, Orlando
• Granted Patent: US 8,961,584 B2
• Time in Patent Office: Days
• US Class Current: 623/1.440
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2002/91533 characterised by the phase between adjacent bands
• CPC Class Codes: A61F 2002/91575 connected peak to trough
• CPC Class Codes: A61F 2230/0013 Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
• CPC Class Codes: A61F 2230/0076 ellipsoidal or ovoid
• CPC Class Codes: A61F 2250/0018 differing in elasticity, stiffness or compressibility
• CPC Class Codes: A61L 2300/606 Coatings
• CPC Class Codes: A61L 31/10 Macromolecular materials
• CPC Class Codes: A61L 31/16 Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence
• CPC Class Codes: Y10S 623/916 Blood vessel

Abstract

A composite stent and a method for making the same are provided.

Claims

1. A stent comprising a structural frame and a regioselective band formed in situ on a region of the structural frame, the regioselective band being formed by drip-coating a material onto the region of the structural frame as the stent rotates, wherein the material has a creep compliance of about 0.5 GPa⁻

1 to about 10.0 GPa<sup>−

1</sup>.

2. The stent of claim 1, wherein the material includes a therapeutic agent.

3. The stent of claim 1, wherein a substance from which the structural frame is made has a modulus of elasticity greater than the modulus of elasticity of the material forming the regioselective band.

4. A stent comprising a structural frame and a regioselective band formed in situ on a region of the structural frame, the regioselective band being formed by dip-coating a material onto the region of the structural frame, wherein the material has a creep compliance of about 0.5 GPa⁻

1 to about 10.0 GPa<sup>−

1</sup>.

5. The stent of claim 4, wherein the material includes a therapeutic agent.

6. The stent of claim 4, wherein a substance from which the structural frame is made has a modulus of elasticity greater than the modulus of elasticity of the material forming the regioselective band.

7. A composite stent, comprising:

an expandable structural frame made from a material including a first material; and

an annular band disposed on the expandable structural frame, the band made from a material including a second material having a creep compliance of about 0.5 GPa<sup>−

1</sup> to about 10.0 GPa<sup>−

1</sup>.

8. The stent of claim 7, wherein a modulus of elasticity of the first material is higher than a modulus of elasticity of the second material.

9. The stent of claim 7, wherein the band is disposed on a region of the expandable structural frame that is substantially adjacent to an end of the frame.

10. The stent of claim 7, wherein the annual band is formed by drip-coating the second material onto the structural frame as the frame rotates.

11. The stent of claim 7, wherein the second material contains a therapeutic agent.

12. The stent of claim 7, wherein the annual band is formed by dip-coating the second material onto the structural frame.

13. A composite stent, comprising:

an expandable structural frame made from a first material having a first modulus of elasticity; and

an annular band disposed on a region of the expandable structural frame, the band made from a second material having a second modulus of elasticity, the second modulus of elasticity being lower than the first modulus of elasticity.

14. A method of producing a stent, the stent comprising a first end, an opposing second end, and a middle segment between the two ends, the method comprising forming a polymeric strip at or adjacent to the first or second end of the stent, wherein the middle segment between the two ends is free from any polymeric strip.

15. The method of claim 14, wherein the polymeric strip includes a drug.