Method for coating lens material
First Claim
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1. A method for forming a device having a covalently bound surface coating, the method comprising:
- providing a reactive monomer comprising a functionalized surfactant dissolved in a solvent;
providing a mold;
coating at least one surface of the mold with the reactive monomer dissolved in the solvent;
providing a device forming monomer mixture to the mold; and
subjecting the monomer mixture and reactive monomer to conditions sufficient to provide a copolymerized device having a covalently bound surface coating.
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Abstract
This invention relates generally to a method for treatment of lens surfaces by first coating the mold material with a reactive macromonomer and subsequently casting and curing the lens forming material along with the coating material present on the surface of the mold. The macromonomer reacts with the lens monomer mix and is covalently bound to the lens matrix. The modified lenses may ultimately show enhanced wettability, inhibition of bacterial adhesion and lower levels of protein and lipid deposition leading to increased comfort and longer wearing times.
51 Citations
12 Claims
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1. A method for forming a device having a covalently bound surface coating, the method comprising:
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providing a reactive monomer comprising a functionalized surfactant dissolved in a solvent;
providing a mold;
coating at least one surface of the mold with the reactive monomer dissolved in the solvent;
providing a device forming monomer mixture to the mold; and
subjecting the monomer mixture and reactive monomer to conditions sufficient to provide a copolymerized device having a covalently bound surface coating. - View Dependent Claims (2, 3, 4)
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5. A method of surface modifying a medical device through the use of complementary reactive copolymerizable functionality between the device forming monomer mix and the reactive macromonomer coated on the mold surface, the method comprising:
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providing a reactive monomer comprising a functionalized surfactant having an HLB value of at least about 8 dissolved in a solvent;
providing a mold;
coating at least a surface of the mold with the reactive monomer;
providing a device forming monomer mixture to the mold; and
subjecting the monomer mixture and reactive monomer to conditions sufficient to provide a copolymerized device having at least one surface modified through the use of complementary reactive copolymerizable functionality between the device forming monomer mix and the reactive macromonomer coated on the mold surface. - View Dependent Claims (6, 7, 8, 9, 10)
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11. A method of surface modifying a medical device, the method comprising:
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providing a reactive monomer comprising a dimethacrylated poloxamer having a molecular weight (number average) of at least 4,500 in a solvent;
providing a mold;
spin coating at least a surface of the mold with the reactive monomer;
providing a device forming monomer mixture comprising silicon containing monomers to the mold; and
subjecting the monomer mixture and reactive monomer to conditions sufficient to provide a copolymerized device having at least one modified surface.
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12. A method of surface modifying a medical device, the method comprising:
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providing a reactive monomer comprising a vinyloxy terminated poloxamer having a molecular weight (number average) of at least 4,500 in a solvent;
providing a mold;
spin coating at least a surface of the mold with the reactive monomer;
providing a device forming monomer mixture comprising silicon containing monomers to the mold; and
subjecting the monomer mixture and reactive monomer to conditions sufficient to provide a copolymerized device having at least one surface modified through the use of complementary reactive copolymerizable functionality between the device forming monomer mix and the reactive macromonomer coated on the mold surface.
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Specification