Biosensor
First Claim
1. A biosensor which comprises a flow channel that is formed on a substrate and is composed of a detection plane for detecting interaction between a physiologically active substance and a test substance and a non-detection plane where said interaction is not detected, wherein the substrate is a metal surface or a metal film and the surfaces of the detection plane and the non-detection plane are modified with a self-assembled monolayer (SAM) having a hydroxy group and a functional group for binding with a physiologically active substance.
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Accused Products
Abstract
An object of the present invention is to provide a biosensor having high capability for suppressing nonspecific protein adsorption and high capability for extracting a target protein. The present invention provides a biosensor which comprises a flow channel that is formed on a substrate and is composed of a detection plane for detecting interaction between a physiologically active substance and a test substance and a non-detection plane where said interaction is not detected, wherein the substrate is a metal surface or a metal film and the surfaces of the detection plane and the non-detection plane are modified with a self-assembled monolayer (SAM) having a hydroxy group and a functional group for binding with a physiologically active substance.
5 Citations
16 Claims
- 1. A biosensor which comprises a flow channel that is formed on a substrate and is composed of a detection plane for detecting interaction between a physiologically active substance and a test substance and a non-detection plane where said interaction is not detected, wherein the substrate is a metal surface or a metal film and the surfaces of the detection plane and the non-detection plane are modified with a self-assembled monolayer (SAM) having a hydroxy group and a functional group for binding with a physiologically active substance.
Specification