Obtaining measurements of light transmitted through an assay test strip
5 Assignments
0 Petitions
Accused Products
Abstract
Systems and methods of obtaining measurements of light transmitted through an assay test strip are described. In one aspect, a test strip is held. The top side of the test strip is illuminated with light. The illuminating light that is transmitted through the test strip and out from the bottom side of the test strip is detected. In another aspect, a diagnostic test system includes a detection system and a retainer. The detection system includes an optical detector that produces a measurement signal in response to light. The retainer holds a test strip so that the top side of the test strip is exposed for illumination and the bottom side of the test strip faces the optical detector.
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Citations
29 Claims
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1. (canceled)
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2. A diagnostic test system, comprising:
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a detection system comprising a first optical detector operable to produce a measurement signal in response to light;
a retainer configured to hold a test strip comprising a flow path for a fluid sample, a bottom side, and a top side opposite the bottom side and supporting a detection zone that has at least one measurement region coupled to the flow path, wherein the retainer is configured to hold the test strip so that the top side is exposed for illumination and the bottom side faces the first optical detector; and
a housing containing the detection system and the retainer and comprising a translucent window permitting light from outside the housing to illuminate the measurement region when the test strip is held by the retainer. - View Dependent Claims (4, 5, 7, 8, 9, 10, 11, 12, 13, 14)
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3. (canceled)
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6. A diagnostic test system, comprising:
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a detection system comprising first and second optical detectors each operable to produce respective measurement signals in response to light;
a retainer configured to hold a test strip comprising a flow path for a fluid sample, a bottom side, and a top side opposite the bottom side and supporting a detection zone that has multiple measurement regions coupled to the flow path, wherein the retainer is configured to hold the test strip so that the top side is exposed for illumination and the bottom side faces the optical detector, wherein the second optical detector faces the bottom side of the test strip when the test strip is held by the retainer, the first and second optical detectors have respective fields of view containing different respective areas of the bottom side of the test strip when the test strip is held by the retainer, and the retainer is configured to hold the test strip in multiple measurement positions relative to the detection system, wherein in each of the measurement positions the field of view of the first optical detector corresponds to an area of the bottom side of the test strip shadowed by a respective one of the measurement regions and the field of view of the second optical detector corresponds to an area of the bottom side of the test strip free of shadowing by any of the measurement regions; and
a data analyzer operable to quantify respective ones of the measurement signals produced by the first optical detector with respect to ones of the measurement signals produced by the second optical detector for each of the measurement positions. - View Dependent Claims (22, 23, 24, 25, 26, 27, 29)
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15-21. -21. (canceled)
Specification