COMPOSITIONS AND METHODS FOR TREATMENT OF BODY WEIGHT CONDITIONS

• US 20070128252A1
• Filed: 10/27/2006
• Published: 06/07/2007
• Est. Priority Date: 03/01/2002
• Status: Abandoned Application

• Current Assignee: Glanbia Nutritionals Ireland Ltd (Glanbia Company-Operative Society Limited)
• Original Assignee: Glanbia Nutritionals Ireland Ltd (Glanbia Company-Operative Society Limited)
• Inventors: Paulsen, Starla, Ward, Loren, Bastian, Eric, Dunne, Colum
• Application Number:
  US11/553,817
• Publication Number:
  US 20070128252A1
• Time in Patent Office: Days
• US Class Current: 424/439
• CPC Class Codes: A23L 2/39 Dry compositions
• CPC Class Codes: A23L 2/52 Adding ingredients adding preservatives A23L2/44
• CPC Class Codes: A23L 33/16 Inorganic salts, minerals or trace elements
• CPC Class Codes: A23L 33/18 Peptides; Protein hydrolysates
• CPC Class Codes: A23L 33/19 Dairy proteins
• CPC Class Codes: A23L 33/30 Dietetic or nutritional methods, e.g. for losing weight A23L33/10 takes precedence
• CPC Class Codes: A61K 35/20 Milk; Whey; Colostrum

Abstract

A nutritional supplement composition having a therapeutically effective amount of peptides is provided for the treatment of body weight conditions. The nutritional supplement may also comprise milk minerals, such as calcium and/or be combined with a protein source including κ-casein fragment 106-169. The nutritional supplement composition is administered in amounts effective for limiting weight gain and/or enhancing weight loss, as well as promoting overall good health, in the treatment of body weight conditions, including overweight and obesity. In one embodiment, the supplement is administered through a calorically restricted diet.

Claims

1. A dietary supplement for treating a body weight condition comprising:

a milk-derived enzyme-inhibiting peptide provided in a therapeutically effective amount for treating the body weight condition.

2. The supplement of claim 1, wherein the body weight condition is obesity.

3. The supplement of claim 1, wherein the milk-derived enzyme-inhibiting peptide is derived from an angiotensin converting enzyme hydrolysate.

4. The supplement of claim 1, wherein the enzyme-inhibiting peptide is angiotensin converting enzyme inhibiting peptide.

5. The supplement of claim 1, wherein the enzyme-inhibiting peptide is derived from milk or whey.

6. The supplement of claim 1 further comprising a milk-derived mineral component.

7. The supplement of claim 6, wherein the milk-derived mineral component includes one or more milk minerals selected from the group consisting of calcium, copper, magnesium, phosphorus, potassium, selenium and zinc.

8. The supplement of claim 6, wherein the milk-derived mineral component includes calcium.

9. The supplement of claim 8, which further maintains bone mineral density or bone mineral content in an individual.

10. The supplement of claim 1 further comprising a dairy protein component.

11. The supplement of claim 10, wherein the dairy protein component is derived from milk or whey.

12. The supplement of claim 10, wherein the dairy protein component includes one or more whey protein isolates.

13. The supplement of claim 10, wherein the dairy protein component includes κ

-casein fragment 106-169.

14. A method of maintaining lean tissue mass in an individual comprising:

administering to the individual a dietary supplement including a milk-derived peptide component and a milk-derived protein component present in a therapeutically effective amounts for maintaining lean tissue mass.

15. The method of claim 14, wherein the lean tissue is lean muscle tissue.

16. The method of claim 14, wherein the milk-derived protein component includes one or more whey protein isolates.

17. The method of claim 14, wherein the ratio of lean tissue mass to fat mass in the individual is at least about 5.25.

18. The method of claim 14, wherein the ratio of lean tissue mass to fat mass in the individual is at least about 6.

19. A method of promoting weight loss in an individual comprising:

administering to the individual an enzyme-inhibiting peptide blend including one or more peptides derived from milk in a calorically restricted diet, wherein the one or more peptides are present in a therapeutically effective amount for promoting weight loss.

20. The method of claim 19, wherein the enzyme-inhibiting peptide blend includes angiotensin converting enzyme inhibiting peptide.