DEVICES, SYSTEMS AND METHODS FOR MEDICAMENT DELIVERY

• US 20070129708A1
• Filed: 02/05/2007
• Published: 06/07/2007
• Est. Priority Date: 02/01/2005
• Status: Active Grant

• Current Assignee: Kaleo, Inc.
• Original Assignee: Intelliject Incorporated
• Inventors: Edwards, Eric, Licata, Mark, Edwards, Evan, Williamson, T.
• Granted Patent: US 8,172,082 B2
• Time in Patent Office: Days
• US Class Current: 604/890.100
• CPC Class Codes: A61M 2005/2013 triggering of discharging means by contact of injector with patient body
• CPC Class Codes: A61M 2005/2026 Semi-automatic, e.g. user activated piston is assisted by additional source of energy
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/2073 preventing premature release, e.g. by making use of a safety lock
• CPC Class Codes: A61M 2005/3128 Incorporating one-way valves, e.g. pressure-relief or non-return valves
• CPC Class Codes: A61M 2039/1083 having a plurality of female connectors, e.g. Luer connectors
• CPC Class Codes: A61M 2039/1088 having a plurality of male connectors, e.g. Luer connectors
• CPC Class Codes: A61M 2205/13 with means for the detection of operative contact with patient, e.g. lip sensor
• CPC Class Codes: A61M 2205/14 Detection of the presence or absence of a tube, a connector or a container in an apparatus
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/3576 with non implanted data transmission devices, e.g. using external transmitter or receiver
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 2205/583 by visual feedback
• CPC Class Codes: A61M 2205/6018 providing set-up signals for the apparatus configuration
• CPC Class Codes: A61M 2205/6036 characterised by physical shape, e.g. array of activating switches
• CPC Class Codes: A61M 5/19 having more than one chamber , e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly surgical glue applicators A61B17/00491
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/2046 : Media being expelled from injector by gas generation, e.g. explosive charge
• CPC Class Codes: A61M 5/2053 : Media being expelled from injector by pressurised fluid or vacuum for infusion A61M5/145, A61M5/155
• CPC Class Codes: A61M 5/2066 : comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/24 : Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/2448 : comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/3129 : Syringe barrels A61M5/3205 and A61M5/50 take precedence
• CPC Class Codes: A61M 5/3204 : Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
• CPC Class Codes: A61M 5/326 : Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
• CPC Class Codes: A61M 5/3287 : Accessories for bringing the needle into the body; Automatic needle insertion A61M5/20, A61M5/31525 take precedence
• CPC Class Codes: G16H 20/17 : delivered via infusion or injection
• CPC Class Codes: G16H 40/20 : for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms

Abstract

An apparatus includes a container defining an internal region configured to contain multiple medicament delivery devices, such as, for example, pen injectors, auto-injectors, inhalers or the like. The container includes an electronic circuit system configured to output a first electronic output associated with a first medicament delivery device contained within the internal region when the first medicament delivery device is removed from the internal region of the container. The electronic circuit system is further configured to output a second electronic output associated with a second medicament delivery device contained within the internal region when the second medicament delivery device is removed from the internal region of the container. The second electronic output is different than the first electronic output. At least one of the first electronic output or the second electronic output is associated with a use instruction.

Claims

1. An apparatus, comprising:

a container defining an internal region configured to contain a plurality of medicament delivery devices, the container including an electronic circuit system configured to output a first electronic output associated with a first medicament delivery device from the plurality of medicament delivery devices when the first medicament delivery device is removed from the internal region and a second electronic output associated with a second medicament delivery device from the plurality of medicament delivery devices when the second medicament delivery device is removed from the internal region, the second electronic output being different than the first electronic output, at least one of the first electronic output or the second electronic output being associated with a use instruction.

2. The apparatus of claim 1, wherein the first electronic output is associated with at least one of an identification of the first medicament delivery device, an identification of a physical condition or an instruction for using the first medicament delivery device.

3. The apparatus of claim 1, wherein the second electronic output is associated with at least one of an identification of the second medicament delivery device, an identification of a physical condition or an instruction for using the second medicament delivery device.

4. The apparatus of claim 1, wherein at least one of the first electronic output or the second electronic output includes at least one of a visual output, an audible output, a haptic output, a wireless communications signal or a wired communications signal.

5. The apparatus of claim 1, wherein at least one of the first electronic output or the second electronic output includes recorded speech in at least one of a plurality of languages.

6. The apparatus of claim 1, wherein:

the internal region of the container includes

a first retainer configured to retain the first medicament delivery device from the plurality of medicament delivery devices within the internal region, and

a second retainer configured to retain the second medicament delivery device from the plurality of medicament delivery devices within the internal region; and

the electronic circuit system includes

a first switch associated with the first retainer, the first switch configured move between a first state and a second state when the first medicament delivery device is removed from the retainer, the electronic circuit system configured to output the first electronic output when the first switch moves between its first state and its second state, and

a second switch associated with the second retainer, the second switch configured move between a first state and a second state when the second medicament delivery device is removed from the second retainer, the electronic circuit system configured to output the second electronic output when the second switch moves between its first state and its second state.

7. The apparatus of claim 1, wherein:

the internal region of the container includes

a first retainer uniquely associated with the first medicament delivery device from the plurality of medicament delivery devices, the first retainer configured to matingly receive a portion of the first medicament delivery device from the plurality of medicament delivery devices, and

a second retainer uniquely associated with the second medicament delivery device from the plurality of medicament delivery devices, the second retainer configured to matingly receive a portion of the second medicament delivery device from the plurality of medicament delivery devices, and

the electronic circuit system includes

a first switch associated with the first retainer, the first switch configured move between a first state and a second state when the first medicament delivery device is removed from the first retainer, the electronic circuit system configured to output the first electronic output when the first switch moves between its first state and its second state;

a second switch associated with the second retainer, the second switch configured move between a first state and a second state when the second medicament delivery device is removed from the second retainer, the electronic circuit system configured to output the second electronic output when the second switch moves between its first state and its second state.

8. The apparatus of claim 7, wherein at least one of the first retainer or the second retainer is a clip, a recessed area within the internal region or an elastic member.

9. The apparatus of claim 1, wherein:

the first medicament delivery device from the plurality of medicament delivery devices includes a label configured to output a signal configured to be received by the electronic circuit system, the signal associated with at least one of a location of the first medicament delivery device, a contents of the first medicament delivery device, an expiration date of the first medicament delivery device, a dosage of the first medicament delivery device or a use instruction associated with the first medicament delivery device; and

the first electronic output is associated with the signal received by the electronic circuit system.

10. The apparatus of claim 1 wherein:

the container includes a movable portion, the internal region of the container being covered when the movable portion is in a first position, at least a portion of the internal region of the container being exposed when the movable portion is in a second position; and

the electronic circuit system is further configured to output a third electronic output when the movable portion moves between its first position and its second position.

11. A kit, comprising:

a medicament delivery device; and

a container defining an internal region configured to contain the medicament delivery device, the container including

a movable portion having a first position and a second position, in the first position, the movable portion covers the internal region of the container, in the second position the internal region of the container is exposed to an area outside the container;

an electronic circuit system;

a first switch configured to move between a first state and a second state when the movable portion moves between its first position and its second position, the first switch operatively coupled to the electronic circuit system such that the electronic circuit system is configured to output a first electronic output when the first switch is moved from its first state to its second state; and

a second switch configured to move between a first state and a second state when the medicament delivery device is removed from the internal region of the container, the second switch operatively coupled to the electronic circuit system such that the electronic circuit system is configured to output a second electronic output when the second switch is moved from its first state to its second state, the second electronic output including an instruction for using the medicament delivery device.

12. The kit of claim 11, wherein the first electronic output includes at least one of a visual output, an audible output, a haptic output, a wireless communications signal or a wired communications signal.

13. The kit of claim 11, wherein the second electronic output includes at least one of a visual output, an audible output, a haptic output, a wireless communications signal or a wired communications signal.

14. The kit of claim 11, wherein at least one of the first electronic output or the second electronic output includes recorded speech.

15. The kit of claim 11, wherein the first electronic output is associated with any one of an identification of the medicament delivery device, an identification of a physical condition, or an instruction for using the medicament delivery device.

16. The kit of claim 11, wherein the second electronic output includes a communications signal configured to notify an emergency response system.

17. The kit of claim 11, wherein the medicament delivery device is a first medicament delivery device, the kit further comprising:

a second medicament delivery device, the internal region being configured to contain the second medicament delivery device; and

a third switch configured to move between a first state and a second state when the second medicament delivery device is removed from the internal region of the container, the third switch operatively coupled to the electronic circuit system such that the electronic circuit system is configured to output a third electronic output when the third switch is moved from its first state to its second state, the third electronic output being different than the second electronic output.

18. The kit of claim 11, wherein the medicament delivery device is at least one of a pen injector, an auto-injector or an inhaler.

19. The apparatus of claim 11, wherein the electronic circuit system includes at least one of a speaker, a light-emitting diode, a liquid crystal display, an organic polymer display, a fiber optic display, a vibrator or a piezo-electric transducer.

20. A processor-readable medium storing code representing instructions to cause a processor to perform a process, the code comprising code to:

output a first electronic output associated with a first medicament delivery device when the first medicament delivery device is removed from a container; and

output a second electronic output associated with a second medicament delivery device when the second medicament delivery device is removed from the container, the second electronic output being different than the first electronic output, at least one of the first electronic output or the second electronic output being associated with a use instruction.

21. The processor-readable medium of claim 20, wherein:

the first electronic output is associated with at least one of an identification of the first medicament delivery device, an identification of a physical condition or an instruction for using the first medicament delivery device; and

the second electronic output is associated with at least one of an identification of the second medicament delivery device, an identification of a physical condition or an instruction for using the second medicament delivery device.

22. The processor-readable medium of claim 20, wherein the code further comprises code to:

receive an electronic input from the first medicament delivery device, the electronic input associated with at least one of a contents of the first medicament delivery device, an expiration date of the first medicament delivery device, a dosage of the first medicament delivery device or a use instruction associated with the first medicament delivery device; and

modify the first electronic output based on the received electronic input.

23. The processor-readable medium of claim 20, wherein the code further comprises code to:

output a third electronic output when a movable portion of the container moves between a first position and a second position.

24. An apparatus, comprising:

a container defining an internal region configured to contain at least a portion of a medicament delivery device;

a retainer configured to be movably coupled to the container, the retainer configured to retain the portion of the medicament delivery device within the internal region;

an electronic circuit system configured to output a first electronic output when the retainer is moved relative to the container and a second electronic output when the medicament delivery device is removed from the internal region, at least one of the first electronic output or the second electronic output being associated with an instruction for using the medicament delivery device.

25. The apparatus of claim 24, wherein:

the first electronic output includes at least one of a visual output, an audible output, a haptic output, a wireless communications signal or a wired communications signal; and

the second electronic output includes at least one of a visual output, an audible output, a haptic output, a wireless communications signal or a wired communications signal.

26. The apparatus of claim 24, wherein at least one of the first electronic output or the second electronic output includes recorded speech.

27. The apparatus of claim 24, wherein the first electronic output is associated with any one of an identification of the medicament delivery device, an identification of a physical condition, or an instruction for using the medicament delivery device.

28. The apparatus of claim 24, wherein the second electronic output is associated with at least one of an identification of the medicament delivery device, an identification of a physical condition or an instruction for using the medicament delivery device.

29. The apparatus of claim 24, wherein the medicament delivery device is at least one of a pen injector, an auto-injector or an inhaler.

30. The apparatus of claim 24, further comprising:

a label configured to be coupled to the medicament delivery device, the label containing an information associated with the medicament delivery device, the information being arranged in a machine-readable format,

the electronic circuit system configured to receive the information, at least one of the first electronic output or the second electronic output including at least a portion of the information.

31. The apparatus of claim 30, wherein the label includes at least one of a magnetic strip containing the information, a bar code portion containing the information or an radio frequency identification tag containing the information.

32. The apparatus of claim 24, wherein at least one of the first electronic output or the second electronic output includes a communications signal configured to notify an emergency response system.

33. An apparatus, comprising:

a container defining an internal region configured to contain at least a portion of a medical injector; and

an electronic circuit system coupled to the container, the electronic circuit system configured to output an electronic output associated with a use of the medical injector.

34. The apparatus of claim 33, further comprising a retainer configured to be movably coupled to the container, the retainer configured to retain the portion of the medical injector within the internal region, the electronic circuit system configured to output the electronic output when the retainer is moved relative to the container.

35. The apparatus of claim 33, further comprising a retainer configured to be movably coupled to the container, the retainer configured to prevent the actuation of the medical injector when in a first position, the retainer configured to allow the actuation of the medical injector when in a second position, the electronic circuit system configured to output the electronic output when the retainer is moved from the first position to the second position.

36. The apparatus of claim 33, further comprising:

a retainer configured to be movably coupled to the container, the retainer configured to prevent the actuation of the medical injector when in a first position, the retainer configured to allow the actuation of the medical injector when in a second position,

the electronic output is a first electronic output,

the electronic circuit system is configured to output the first electronic output when the medical injector is moved relative to the container, and

the electronic circuit system configured to output a second electronic output when the retainer is moved from the first position to the second position.

37. The apparatus of claim 33, wherein the electronic output includes recorded speech.

38. The apparatus of claim 33, further comprising:

a label configured to be coupled to the medical injector, the label containing an information associated with the medical injector, the information being arranged in a machine-readable format,

the electronic circuit system being configured to receive the information, the electronic output including at least a portion of the information.

39. The apparatus of claim 38, wherein the label includes at least one of a magnetic strip containing the information, a bar code portion containing the information or an radio frequency identification tag containing the information.