Tissue Repair and Replacement
First Claim
1. A device for tissue repair or replacement, comprising first and second components having different relative rates of in vivo degradation, the first component having a higher rate of in vivo degradation than the second component, and the first and second components being arranged relative to each other so that, after implantation of the deice, the first component degrades in vivo leaving a scaffold formed of the second component, the scaffold having pores into which tissue can infiltrate, wherein the first and second components comprise ceramics.
1 Assignment
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Accused Products
Abstract
Tissue fixation devices are provided. The devices include a first component and a second component, the components having different rates of in vivo degradation. The first component and second component are arranged so that, upon degradation of one of the components, the other component provides a scaffold into which bone can grow.
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Citations
22 Claims
- 1. A device for tissue repair or replacement, comprising first and second components having different relative rates of in vivo degradation, the first component having a higher rate of in vivo degradation than the second component, and the first and second components being arranged relative to each other so that, after implantation of the deice, the first component degrades in vivo leaving a scaffold formed of the second component, the scaffold having pores into which tissue can infiltrate, wherein the first and second components comprise ceramics.
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8. A device for tissue repair or replacement, comprising:
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a porous ceramic structure comprising a first ceramic; and
a second ceramic disposed in pores of the ceramic structure, the device being substantially non-porous prior to implantation in a patient. - View Dependent Claims (9, 10, 11, 12, 13, 14, 15, 16)
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17. A method of tissue repair or replacement, comprising implanting in a patient a device including first and second components having different relative rates of in vivo degradation, the first component having a higher rate of in vivo degradation than the second component, and the first and second components being arranged relative to each other so that, after implantation of the device, the first component degrades in vivo leaving a scaffold formed of the second component, the scaffold having pores into which tissue can infiltrate, wherein the first and second components comprise ceramics.
- 18. A method of making a device for tissue repair or replacement, comprising forming a porous scaffold of a first component, and infiltrating the porous scaffold with a second component, wherein the first and second components comprise ceramics.
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22. A device for tissue repair or replacement, comprising first and second components having different relative rates of in vivo degradation, the first component having a higher rate of in vivo degradation than the second component, and the first and second components being arranged relative to each other so that, after implantation of the device, the first component degrades in vivo, wherein the first and second components comprise ceramics.
Specification