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Bioinformatically detectable group of novel regulatory genes and uses thereof

  • US 20070134655A1
  • Filed: 11/16/2003
  • Published: 06/14/2007
  • Est. Priority Date: 11/14/2002
  • Status: Active Grant
First Claim
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1. A bioinformatically detectable novel gene encoding substantially pure DNA wherein:

  • RNA encoded by said bioinformatically detectable novel gene is about 18 to about 24 nucleotides in length, and originates from an RNA precursor, which RNA precursor is about 50 to about 120 nucleotides in length;

    a nucleotide sequence of a first half of said RNA precursor is a partial or accurate inversed reversed sequence of a nucleotide sequence of a second half thereof;

    a nucleotide sequence of said RNA encoded by said novel gene is a partial or accurate inversed reversed sequence of a nucleotide sequence of a binding site associated with at least one target gene;

    said novel gene cannot be detected by either of the following;

    a visually discernable whole body phenotype; and

    detection of 99.9% of RNA species shorter than 25 nucleotides expressed in a tissue sample; and

    a function of said novel gene is bioinformatically deducible.

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