CONDITIONING DEVICE FOR LIQUID HANDLING SYSTEM LIQUIDS

• US 20070140916A1
• Filed: 12/19/2006
• Published: 06/21/2007
• Est. Priority Date: 12/20/2005
• Status: Abandoned Application

• Current Assignee: Tecan Trading AG (Tecan Group AG)
• Original Assignee: Tecan Trading AG (Tecan Group AG)
• Inventors: Spiss, Markus
• Application Number:
  US11/612,552
• Publication Number:
  US 20070140916A1
• Time in Patent Office: Days
• US Class Current: 422/100
• CPC Class Codes: B01D 19/0036 Flash degasification the other groups take precedence
• CPC Class Codes: B01D 19/0042 modifying the liquid flow B01D19/0021 takes precedence
• CPC Class Codes: B01D 19/0047 Atomizing, spraying, trickling
• CPC Class Codes: B01D 19/0063 Regulation, control including valves and floats for construction and details of valves F16K
• CPC Class Codes: B01L 2200/0684 Venting, avoiding backpressure, avoid gas bubbles
• CPC Class Codes: B01L 2400/0487 fluid pressure, pneumatics
• CPC Class Codes: B01L 3/021 Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
• CPC Class Codes: B01L 3/0293 for liquids
• CPC Class Codes: C02F 1/20 by degassing, i.e. liberation of dissolved gases degasification of liquids in general B01D19/00; arrangement of degassing apparatus in boiler feed supply F22D
• CPC Class Codes: C02F 2201/008 Mobile apparatus and plants, e.g. mounted on a vehicle
• CPC Class Codes: G01N 2035/1018 Detecting inhomogeneities, e.g. foam, bubbles, clots
• CPC Class Codes: G01N 35/1016 Control of the volume dispensed or introduced

Abstract

A device for conditioning a system liquid for a liquid handling apparatus has a degassing chamber for degassing the system liquid, with a system liquid injection point, a system liquid drain line and a gas train line. The device has a collection chamber for degassing liquid, which is separated from the degassing chamber and is connected via a recirculation pump to the system liquid drain line. At least one such device can be integrated into a mobile facility for conditioning a system liquid for a liquid handling apparatus. A liquid handling workstation having at least one such liquid handling apparatus for pipetting or dispensing liquid samples with the aid of a system liquid or such a liquid handling apparatus may also comprise at least one such device.

Claims

1. A device (1) for conditioning a system liquid for a liquid handling apparatus, which comprises a degassing chamber (2) for degassing the system liquid, the degassing chamber (2) comprising a system liquid injection point (3), a system liquid drain line (4) and a gas drain line (5),

wherein the device comprises a collection chamber (6) for degassed system liquid, which is spatially separated from the degassing chamber (2) and which is connected via a recirculation pump (7) to the system liquid drain line (4) of the degassing chamber (2).

2. The device (1) according to claim 1,

wherein the degassing chamber (2) comprises a splash wall (8), which is situated on an injection axis (10) running through the system liquid injection point (3) and its injection nozzle (9) in such a way that the injected system liquid impacts on the splash wall (8) and is swirled.

3. The device (1) according to claim 2,

wherein the splash wall (8) encloses an angle with the injection axis (10), which is less than 90°

, this angle preferably being directed upward.

4. The device (1) according to claim 2,

wherein the degaussing chamber (2) comprises a gas outflow connecting piece (11), which is situated above the injection nozzle (9) and in the injection direction after the injection nozzle (9).

5. The device (1) according to claim 2,

wherein the degassing chamber (2) comprises a system liquid intake connecting piece (12), which is situated below the injection nozzle (9) and in the injection direction after the injection nozzle (9).

6. The device (1) according to the claim 4,

wherein the gas outflow connecting piece (11) and the system liquid intake connecting piece (12) represent a cylinder with a part of the degassing chamber (2) lying between them, into which the remaining part of the degassing chamber (2), which is also cylindrical, discharges at a right angle.

7. The device (1) according to claim 6,

wherein the injection nozzle (9) and the splash wall (8) are situated symmetrically on the injection axis (10), this injection axis (10) being identical to the cylinder axis of the remaining part of the degassing chamber (2).

8. The device (1) according to claim 6,

wherein the splash wall (8) is situated at least partially in this cylindrical remaining part of the degassing chamber (2).

9. The device (1) according to claim 1,

wherein the collection chamber (6) has an outlet (13) for degassed system liquid and is implemented as a chamber between two cylinders (14,15), which are movable one inside the other end are sealed to one another, or as a chamber in a flexible bag.

10. The device (1) according to claim 9,

wherein the outer cylinder (14) is implemented as a collection chamber (6) for degassed system liquid and the inner cylinder (15) is implemented as a reservoir chamber (16) for the system liquid to be degassed.

11. The device (1) according to claim 1,

wherein the collection chamber (6) is implemented as an individually transportable system liquid canister.

12. The device (1) according to claim 1,

which comprises a reservoir chamber (16) or a supply line (17) for the system liquid to be degassed.

13. The device (1) according to claim 1,

which comprises a heater (42) for the system liquid to be degassed and/or a cooler (43) for the degassed system liquid.

14. The device (1) according to claim 13,

wherein the heater (42) for the system liquid to be degassed and the cooler (43) for the degassed liquid are integrated in a heating-cooling apparatus (44), the heating-cooling apparatus (44) comprising at least one Peltier element (45).

15. The device (1) according to claim 1,

which comprises a thermostat for thermostatting or controlling the temperature of the degassed system liquid in the collection chamber (6).

16. A mobile facility (18) for conditioning a system liquid for a liquid handling apparatus,

wherein the mobile facility comprises at least one device (1) according to claim 1 that is connectable to at least one liquid handling apparatus.

17. A liquid handling apparatus for pipetting or dispensing liquid samples with the aid of a system liquid,

wherein this liquid handling apparatus comprises at least one device (1) for conditioning the system liquid according to claim 1.

18. A liquid handling workstation (19) having at least one liquid handling apparatus for pipetting or dispensing liquid samples with the aid of a system liquid,

wherein this liquid handling workstation comprises at least one device (1) for conditioning the system liquid according to claim 1.

19. A use of a device (1) for conditioning, particularly for degassing, a system liquid for a liquid handling apparatus, according to claim 1.