Wound or surgical dressing

• US 20070141130A1
• Filed: 12/15/2005
• Published: 06/21/2007
• Est. Priority Date: 12/15/2005
• Status: Active Grant

• Current Assignee: Avent Incorporated (Avanos Medical, Inc.)
• Original Assignee: Kimberly-Clark Worldwide Incorporated (Kimberly-Clark Corporation)
• Inventors: Sayre, Curtis, Villanueva, Julie
• Granted Patent: US 7,985,209 B2
• Time in Patent Office: Days
• US Class Current: 424/445
• CPC Class Codes: A61L 15/46 Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
• CPC Class Codes: A61L 2300/102 Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
• CPC Class Codes: A61L 2300/404 Biocides, antimicrobial agents, antiseptic agents
• CPC Class Codes: A61L 2300/80 characterised by a special chemical form

Abstract

A wound or surgical dressing is disclosed. The wound or surgical dressing is configured to cover or surround a wound, a surgical incision, or any type of skin irritation. In accordance with the present disclosure, the wound or surgical dressing is treated with a bacteriostatic composition that is capable of binding and trapping negatively charged matter, such as bacteria, pathogens, and the like. The bacteriostatic composition comprises a cationic polymer, a cationic oligomer, or particles coated with a cationic material. The bacteriostatic composition is bonded to the wound or surgical dressing in a manner such that the bacteriostatic composition is not substantially transferred to a patient being treated.

Claims

1. A wound or surgical dressing comprising:

a substrate configured to contact or surround a wound or surgical site; and

a bacteriostatic composition applied to the substrate, the bacteriostatic composition being located on the substrate so as to contact a patient at or near a wound or surgical site, the bacteriostatic composition being bonded to the substrate so that the composition does not substantially transfer to the patient, the bacteriostatic composition comprising a chemical compound having a net positive charge for binding with negatively charged matter, the chemical compound comprising a cationic polymer, a cationic oligomer, a nanoparticle, or mixtures thereof.

2. A wound or surgical dressing as defined in claim 1, wherein the chemical compound comprises an inorganic ion, complex, molecule, or oligomer.

3. A wound or surgical dressing as defined in claim 1, wherein the chemical compound comprises an aluminum oligomer or an aluminum salt.

4. A wound or surgical dressing as defined in claim 3, wherein the aluminum oligomer comprises aluminum chlorohydrate or aluminum chlorohydrol.

5. A wound or surgical dressing as defined in claim 1, wherein the chemical compound comprises an epichlorohydrin-functionalized polyamine.

6. A wound or surgical dressing as defined in claim 1, wherein the chemical compound comprises particles coated with a cationic polymer or a cationic oligomer or comprises aluminum particles or alumina particles.

7. A wound or surgical dressing as defined in claim 1, wherein the chemical compound comprises polyethyleneimine or poly(methacryloxyethyl)trimethylammonium bromide poly(acrylic) acid.

8. A wound or surgical dressing as defined in claim 1, wherein the bacteriostatic composition is applied to a treated area on the substrate, the composition being applied to the treated area in an amount from about 0.01% to about 20% by weight.

9. A wound or surgical dressing as defined in claim 1, wherein the bacteriostatic composition is applied to a treated area on the substrate, the composition being applied to the treated area in an amount from about 0.05% to about 10% by weight.

10. A wound or surgical dressing as defined in claim 1, wherein the chemical compound is crosslinked.

11. A wound or surgical dressing as defined in claim 1, wherein the substrate comprises a gauze.

12. A wound or surgical dressing as defined in claim 1, wherein the substrate comprises an elastic material.

13. A wound or surgical dressing as defined in claim 12, wherein the elastic material comprises a stretch-bonded laminate or a neck-bonded laminate.

14. A wound or surgical dressing as defined in claim 1, wherein the substrate comprises a spunbond web, a meltblown web, or a laminate thereof.

15. A wound or surgical dressing as defined in claim 1, wherein the substrate comprises a spunbond/meltblown/spunbond laminate.

16. A wound or surgical dressing as defined in claim 1, wherein the substrate comprises a coform web.

17. A wound or surgical dressing as defined in claim 1, wherein the substrate comprises an airlaid web.

18. A wound or surgical dressing as defined in claim 1, wherein the substrate comprises a bonded carded web, a wetlaid web, a foam, a film, a woven fabric, or a knitted fabric.

19. A wound or surgical dressing as defined in claim 1, wherein the substrate comprises a hydroentangled web.

20. A wound or surgical dressing as defined in claim 19, wherein the hydroentangled web comprises pulp fibers and synthetic fibers.

21. A wound or surgical dressing as defined in claim 1, wherein the chemical compound binds with negatively charged bacteria, pathogens, fungi, ions, or molecules.

22. A wound or surgical dressing as defined in claim 1, wherein the chemical compound once bonded to the substrate reduces bacterial growth according to a bacteria binding procedure by at least about 50%.

23. A wound or surgical dressing as defined in claim 1, wherein the chemical compound once bonded to the substrate reduces bacterial growth according to a bacteria binding procedure by at least about 90%.

24. A wound or surgical dressing as defined in claim 1, wherein the chemical compound once bonded to the substrate reduces bacterial growth according to a bacteria binding procedure by at least about 99%.

25. A wound or surgical dressing as defined in claim 1, wherein the wound or surgical dressing comprises an adhesive bandage.

26. A wound or surgical dressing as defined in claim 1, wherein the wound or surgical dressing comprises a wrapping.

27. A wound or surgical dressing comprising:

a substrate configured to contact or surround a wound or surgical site, the substrate comprising a material selected from the group consisting of gauze, a stretch-bonded laminate, a neck-bonded laminate, a spunbond web, a meltblown web, a coform web, an airlaid web, a wetlaid web, and a hydroentangled web; and

a bacteriostatic composition applied to the substrate, the bacteriostatic composition being located on the substrate so as to contact a patient at or near a wound or surgical site, the bacteriostatic composition being bonded to the substrate so that the composition does not substantially transfer to the patient, the bacteriostatic composition comprising a chemical compound having a net positive charge for binding with negatively charged matter, the chemical compound comprising an aluminum salt, an aluminum ion, an aluminum complex, an aluminum molecule, or an aluminum oligomer.

28. A wound or surgical dressing as defined in claim 27, wherein the chemical compound comprises particles.

29. A wound or surgical dressing as defined in claim 27, wherein the chemical compound is covalently bonded to the substrate.

30. A wound or surgical dressing as defined in claim 27, wherein the chemical compound comprises aluminum chlorohydrate or aluminum chlorohydrol.