Flow-path inserts for wet/dry automatic injectors
First Claim
1. An automatic injection device containing a pre-loaded charge of medicament for automatically self-administering the medicament upon actuation thereof, the device comprising:
- a housing;
a medicament chamber disposed in the housing, the medicament chamber including a first compartment containing a first medicament portion, and a second compartment containing a second medicament portion to be mixed with the first medicament portion;
a seal structure between the first compartment and the second compartment, the seal structure being initially in a sealing condition that maintains the first compartment separate from the second compartment, the seal structure being converted to a mixing condition as a result of activation of the device;
a needle assembly that dispenses the medicament charge from the medicament chamber, the needle assembly having a rearward opening with a diameter that is less than a diameter of the medicament chamber;
an insert mounted in a forward end of the medicament chamber adjacent the needle assembly, the insert defining a tapering flow pathway that tapers radially inward as it extends axially forward;
an activation assembly carried by the housing and including a stored energy source, wherein activation of the activation assembly releases the stored energy from the stored energy source, causing the seal structure to be converted from the sealing condition to the mixing condition, and thereby causing or allowing the first and second medicament portions to be mixed, directed by the insert radially inward toward the rearward opening in the needle assembly, and forced through the needle assembly.
6 Assignments
0 Petitions
Accused Products
Abstract
An automatic medicament injector having a compartment for a dry medicament component and a compartment for a wet medicament component. The two compartments are separated by a seal structure that converts from a sealing condition into a mixing condition when the device is activated. The seal structure includes a wiper that scrapes the interior walls in the dry component compartment to prevent the dry component from accumulating at the seal/glass interface. A tapered insert funnels the mixed medicament components to an attached needle assembly, but can be removed when the device is filled. A filter is provided between the medicament compartments and the needle assembly. A chamber between the filter and the needle allows for better flow through the filter. An actuation assembly drives the seal structure into the mixing condition and forces the mixed medicament through the needle and into the user.
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Citations
18 Claims
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1. An automatic injection device containing a pre-loaded charge of medicament for automatically self-administering the medicament upon actuation thereof, the device comprising:
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a housing;
a medicament chamber disposed in the housing, the medicament chamber including a first compartment containing a first medicament portion, and a second compartment containing a second medicament portion to be mixed with the first medicament portion;
a seal structure between the first compartment and the second compartment, the seal structure being initially in a sealing condition that maintains the first compartment separate from the second compartment, the seal structure being converted to a mixing condition as a result of activation of the device;
a needle assembly that dispenses the medicament charge from the medicament chamber, the needle assembly having a rearward opening with a diameter that is less than a diameter of the medicament chamber;
an insert mounted in a forward end of the medicament chamber adjacent the needle assembly, the insert defining a tapering flow pathway that tapers radially inward as it extends axially forward;
an activation assembly carried by the housing and including a stored energy source, wherein activation of the activation assembly releases the stored energy from the stored energy source, causing the seal structure to be converted from the sealing condition to the mixing condition, and thereby causing or allowing the first and second medicament portions to be mixed, directed by the insert radially inward toward the rearward opening in the needle assembly, and forced through the needle assembly. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. An automatic injection device containing a pre-loaded charge of medicament for automatically administering the medicament upon actuation thereof, the device comprising:
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a housing;
a chamber disposed in the housing, the chamber including a first compartment containing a first medicament portion, and a second compartment containing a second medicament portion to be mixed with the first medicament portion;
a seal structure between the first compartment and the second compartment, the seal structure initially in a sealed condition that maintains the first compartment separate from the second compartment, the seal structure converting to a mixing condition in response to activation of the device;
a needle assembly that dispenses the medicament charge from the chamber, the needle assembly having a rearward opening with a diameter that is less than a diameter of a forward end of the chamber;
an insert mounted in the forward end of the chamber adjacent the needle assembly, the insert comprising a funnel portion having an outside surface that sealingly engages the inner wall of the chamber, the insert having a small opening at one end of the funnel portion facing the needle assembly and a large opening at an opposite end of the funnel portion facing the chamber, the funnel portion having a flow-path that tapers radially inward from the chamber to the needle assembly; and
an activation assembly disposed in the housing and including a stored energy source, wherein activation of the activation assembly releases the stored energy from the stored energy source causing the seal structure to convert from the sealed condition to the mixing condition, wherein the first and second medicament portions are mixed, directed by the insert radially inward toward the rearward opening in the needle assembly, and forced through the needle assembly. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16, 17, 18)
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Specification