Removal of fat cells by PDT
First Claim
12. A photosensitizer formulation for reducing adipose tissue comprising:
- a hydrophobic macrocycle porphyrin species; and
a carrier.
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Accused Products
Abstract
A non-surgical, minimally invasive PhotoDynamic Therapy (PDT) method for destruction of undesirable fat cells in the body, which cause obesity, obesity related health problems, and undesirable body contours. In this method photosensitizing agents are formulated into a liposomal formulation or into other delivery means for administering the drug systemically, directly by injection and/or topical application. The photosensitizing formulation is selectively targeted at adipose tissue in the subcutaneous layer. Photosensitized adipose cells are illuminated with a predetermined wavelength of light energy known to initiate a photo cytotoxic effect. The light energy for photoactivation of the photosensitizing agent may be applied interstitially through optical fibers with or without a diffuser tip. Alternatively, a photosensitizing agent is selected to have an activating wavelength which permits external irradiation through the skin. The method ensures safe and permanent fat reduction, minimizes trauma to the area of treatment and also hastens the healing process. A lasting and permanent effect is provided in regions of fat accumulation as the adipose cells are permanently destroyed. This approach is also effective for fat deposits which do not respond to other treatments.
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Citations
15 Claims
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12. A photosensitizer formulation for reducing adipose tissue comprising:
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a hydrophobic macrocycle porphyrin species; and
a carrier. - View Dependent Claims (1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 13, 14, 15)
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Specification